Fatal Case of Heartland Virus Disease Acquired in the Mid-Atlantic Region, United States
We describe a reported fatal case of HRTV infection in the Maryland and Virginia region, states not widely recognized to have human HRTV disease cases. The range of HRTV could be expanding in the United States.PMID:36821867 | DOI:10.3201/eid2905.221488 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - February 23, 2023 Category: Infectious Diseases Authors: Sichen Liu Suraj Kannan Monica Meeks Sandra Sanchez Kyle W Girone James C Broyhill Roosecelis Brasil Martines Joshua Bernick Lori Flammia Julia Murphy Susan L Hills Kristen L Burkhalter Janeen J Laven David Gaines Christopher J Hoffmann Source Type: research
Fatal Case of Heartland Virus Disease Acquired in the Mid-Atlantic Region, United States
We describe a reported fatal case of HRTV infection in the Maryland and Virginia region, states not widely recognized to have human HRTV disease cases. The range of HRTV could be expanding in the United States.PMID:36821867 | DOI:10.3201/eid2905.221488 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - February 23, 2023 Category: Infectious Diseases Authors: Sichen Liu Suraj Kannan Monica Meeks Sandra Sanchez Kyle W Girone James C Broyhill Roosecelis Brasil Martines Joshua Bernick Lori Flammia Julia Murphy Susan L Hills Kristen L Burkhalter Janeen J Laven David Gaines Christopher J Hoffmann Source Type: research
Fatal Case of Heartland Virus Disease Acquired in the Mid-Atlantic Region, United States
S. Liu et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - February 23, 2023 Category: Infectious Diseases Source Type: research
Antiviral activity and mechanism of the antifungal drug, anidulafungin, suggesting its potential to promote treatment of viral diseases
CONCLUSIONS: The results demonstrated that the antifungal drug, anidulafungin, could effectively inhibit virus infection by interfering with virus entry, suggesting it may be utilized for the clinical treatment of infectious viral diseases, in addition to its FDA-approved use as an antifungal. The findings also suggested to further evaluate the anti-viral effects of echinocandins and their clinical importance for patients with infection of viruses, which may promote therapeutic strategies as well as treatments and improve outcomes pertaining to various viral and fungal diseases.PMID:36266654 | DOI:10.1186/s12916-022-02558-z (Source: Herpes)
Source: Herpes - October 21, 2022 Category: Infectious Diseases Authors: Shu Shen Yaxian Zhang Zhiyun Yin Qiong Zhu Jingyuan Zhang Tiantian Wang Yaohui Fang Xiaoli Wu Yuan Bai Shiyu Dai Xijia Liu Jiayin Jin Shuang Tang Jia Liu Manli Wang Yu Guo Fei Deng Source Type: research
Antiviral activity and mechanism of the antifungal drug, anidulafungin, suggesting its potential to promote treatment of viral diseases
CONCLUSIONS: The results demonstrated that the antifungal drug, anidulafungin, could effectively inhibit virus infection by interfering with virus entry, suggesting it may be utilized for the clinical treatment of infectious viral diseases, in addition to its FDA-approved use as an antifungal. The findings also suggested to further evaluate the anti-viral effects of echinocandins and their clinical importance for patients with infection of viruses, which may promote therapeutic strategies as well as treatments and improve outcomes pertaining to various viral and fungal diseases.PMID:36266654 | DOI:10.1186/s12916-022-02558-z (Source: Herpes)
Source: Herpes - October 21, 2022 Category: Infectious Diseases Authors: Shu Shen Yaxian Zhang Zhiyun Yin Qiong Zhu Jingyuan Zhang Tiantian Wang Yaohui Fang Xiaoli Wu Yuan Bai Shiyu Dai Xijia Liu Jiayin Jin Shuang Tang Jia Liu Manli Wang Yu Guo Fei Deng Source Type: research
Isolation of Heartland Virus from Lone Star Ticks, Georgia, USA, 2019
Emerg Infect Dis. 2022 Apr;28(4):786-792. doi: 10.3201/eid2804.211540.ABSTRACTReport of a human death and exposure of white-tailed deer to Heartland virus (HRTV) in Georgia, USA, prompted the sampling of questing ticks during 2018-2019 in 26 sites near where seropositive deer were captured and the residence of the human case-patient. We processed 9,294 Amblyomma americanum ticks in pools by virus isolation in Vero E6 cells and reverse transcription PCR. Positive pools underwent whole-genome sequencing. Three pools were positive for HRTV (minimum infection rate 0.46/1,000 ticks) and none for Bourbon virus. Cell cultures con...
Source: Emerging Infectious Diseases - March 23, 2022 Category: Infectious Diseases Authors: Yamila Romer Kayla Adcock Zhuoran Wei Daniel G Mead Oscar Kirstein Steph Bellman Anne Piantadosi Uriel Kitron Gonzalo M Vazquez-Prokopec Source Type: research
Isolation of Heartland Virus from Lone Star Ticks, Georgia, USA, 2019
Emerg Infect Dis. 2022 Apr;28(4):786-792. doi: 10.3201/eid2804.211540.ABSTRACTReport of a human death and exposure of white-tailed deer to Heartland virus (HRTV) in Georgia, USA, prompted the sampling of questing ticks during 2018-2019 in 26 sites near where seropositive deer were captured and the residence of the human case-patient. We processed 9,294 Amblyomma americanum ticks in pools by virus isolation in Vero E6 cells and reverse transcription PCR. Positive pools underwent whole-genome sequencing. Three pools were positive for HRTV (minimum infection rate 0.46/1,000 ticks) and none for Bourbon virus. Cell cultures con...
Source: Emerging Infectious Diseases - March 23, 2022 Category: Infectious Diseases Authors: Yamila Romer Kayla Adcock Zhuoran Wei Daniel G Mead Oscar Kirstein Steph Bellman Anne Piantadosi Uriel Kitron Gonzalo M Vazquez-Prokopec Source Type: research
Isolation of Heartland Virus from Lone Star Ticks, Georgia, USA, 2019
Emerg Infect Dis. 2022 Apr;28(4):786-792. doi: 10.3201/eid2804.211540.ABSTRACTReport of a human death and exposure of white-tailed deer to Heartland virus (HRTV) in Georgia, USA, prompted the sampling of questing ticks during 2018-2019 in 26 sites near where seropositive deer were captured and the residence of the human case-patient. We processed 9,294 Amblyomma americanum ticks in pools by virus isolation in Vero E6 cells and reverse transcription PCR. Positive pools underwent whole-genome sequencing. Three pools were positive for HRTV (minimum infection rate 0.46/1,000 ticks) and none for Bourbon virus. Cell cultures con...
Source: Emerging Infectious Diseases - March 23, 2022 Category: Infectious Diseases Authors: Yamila Romer Kayla Adcock Zhuoran Wei Daniel G Mead Oscar Kirstein Steph Bellman Anne Piantadosi Uriel Kitron Gonzalo M Vazquez-Prokopec Source Type: research
Isolation of Heartland Virus from Lone Star Ticks, Georgia, USA, 2019
Emerg Infect Dis. 2022 Apr;28(4):786-792. doi: 10.3201/eid2804.211540.ABSTRACTReport of a human death and exposure of white-tailed deer to Heartland virus (HRTV) in Georgia, USA, prompted the sampling of questing ticks during 2018-2019 in 26 sites near where seropositive deer were captured and the residence of the human case-patient. We processed 9,294 Amblyomma americanum ticks in pools by virus isolation in Vero E6 cells and reverse transcription PCR. Positive pools underwent whole-genome sequencing. Three pools were positive for HRTV (minimum infection rate 0.46/1,000 ticks) and none for Bourbon virus. Cell cultures con...
Source: Emerging Infectious Diseases - March 23, 2022 Category: Infectious Diseases Authors: Yamila Romer Kayla Adcock Zhuoran Wei Daniel G Mead Oscar Kirstein Steph Bellman Anne Piantadosi Uriel Kitron Gonzalo M Vazquez-Prokopec Source Type: research
Isolation of Heartland Virus from Lone Star Ticks, Georgia, USA, 2019
Y. Romer et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - March 16, 2022 Category: Infectious Diseases Source Type: research
Transovarial Transmission of Heartland Virus by Invasive Asian Longhorned Ticks under Laboratory Conditions
Emerg Infect Dis. 2022 Mar;28(3):726-729. doi: 10.3201/eid2803.210973.ABSTRACTWe demonstrated experimental acquisition and transmission of Heartland bandavirus by Haemaphysalis longicornis ticks. Virus was detected in tick salivary gland and midgut tissues. A total of 80% of mice exposed to 1 infected tick seroconverted, suggesting horizontal transmission. H. longicornis ticks can transmit the virus in the transovarial mode.PMID:35202534 | DOI:10.3201/eid2803.210973 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - February 24, 2022 Category: Infectious Diseases Authors: Wilson R Raney Josiah B Perry Meghan E Hermance Source Type: research
Transovarial Transmission of Heartland Virus by Invasive Asian Longhorned Ticks under Laboratory Conditions
Emerg Infect Dis. 2022 Mar;28(3):726-729. doi: 10.3201/eid2803.210973.ABSTRACTWe demonstrated experimental acquisition and transmission of Heartland bandavirus by Haemaphysalis longicornis ticks. Virus was detected in tick salivary gland and midgut tissues. A total of 80% of mice exposed to 1 infected tick seroconverted, suggesting horizontal transmission. H. longicornis ticks can transmit the virus in the transovarial mode.PMID:35202534 | DOI:10.3201/eid2803.210973 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - February 24, 2022 Category: Infectious Diseases Authors: Wilson R Raney Josiah B Perry Meghan E Hermance Source Type: research
Transovarial Transmission of Heartland Virus by Invasive Asian Longhorned Ticks under Laboratory Conditions
W. R. Raney et al. (Source: Emerging Infectious Diseases Journal)
Source: Emerging Infectious Diseases Journal - February 7, 2022 Category: Infectious Diseases Source Type: research
Heartland Virus Transmission, Suffolk County, New York, USA
Emerg Infect Dis. 2021 Oct 14;27(12). doi: 10.3201/eid2712.211426. Online ahead of print.ABSTRACTDuring 2018, Heartland virus RNA was detected in an Amblyomma americanum tick removed from a resident of Suffolk County, New York, USA. The persons showed seroconversion. Tick surveillance and white-tailed deer (Odocoileus virginianus) serosurveys showed widespread distribution in Suffolk County, emphasizing a need for disease surveillance anywhere A. americanum ticks are established or emerging.PMID:34648421 | DOI:10.3201/eid2712.211426 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - October 14, 2021 Category: Infectious Diseases Authors: Alan P Dupuis Melissa A Prusinski Collin O'Connor Joseph G Maffei Kiet A Ngo Cheri A Koetzner Michael P Santoriello Christopher L Romano Guang Xu Fumiko Ribbe Scott R Campbell Stephen M Rich P Bryon Backenson Laura D Kramer Alexander T Ciota Source Type: research
Heartland Virus Transmission, Suffolk County, New York, USA
Emerg Infect Dis. 2021 Oct 14;27(12). doi: 10.3201/eid2712.211426. Online ahead of print.ABSTRACTDuring 2018, Heartland virus RNA was detected in an Amblyomma americanum tick removed from a resident of Suffolk County, New York, USA. The persons showed seroconversion. Tick surveillance and white-tailed deer (Odocoileus virginianus) serosurveys showed widespread distribution in Suffolk County, emphasizing a need for disease surveillance anywhere A. americanum ticks are established or emerging.PMID:34648421 | DOI:10.3201/eid2712.211426 (Source: Emerging Infectious Diseases)
Source: Emerging Infectious Diseases - October 14, 2021 Category: Infectious Diseases Authors: Alan P Dupuis Melissa A Prusinski Collin O'Connor Joseph G Maffei Kiet A Ngo Cheri A Koetzner Michael P Santoriello Christopher L Romano Guang Xu Fumiko Ribbe Scott R Campbell Stephen M Rich P Bryon Backenson Laura D Kramer Alexander T Ciota Source Type: research
