Maximizing the Scientific Value of Existing Biospecimen Collections (R21 Clinical Trial Not Allowed)
Funding Opportunity RFA-OD-21-004 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to invite R21 applications to stimulate exploratory research relevant to the mission of the Food and Drug Administration (FDA) - Center for Tobacco Products (CTP) using existing (publicly available) biospecimens currently stored in repositories in the United States. This will include, but not be limited to, collections associated with the Population Assessment of Tobacco and Health (PATH) Study, the National Health and Nutrition Examination Survey (NHANES), the National Heart, Lung...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 10, 2021 Category: Research Source Type: funding
Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH) Multisite Resource and Coordinating Center (U24 Clinical Trial Required)
Funding Opportunity RFA-HL-22-008 from the NIH Guide for Grants and Contracts. This FOA runs in parallel with the companion FOA (RFA-HL-22-007). This FOA uses the bi-phasic, milestone-driven UG3/UH3 cooperative agreement mechanism (UG3/UH3), and runs in parallel with a companion FOA (RFA-HL-22-008), which seeks applications for a Data Coordinating Center (DCC). Awards made under this FOA will support a milestone-driven planning phase, including feasibility studies and pilot trials for up to 2 years, with possible transition to an implementation phase (UH3) for up to five additional years. Only UG3 trials that meet the s...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 22, 2021 Category: Research Source Type: funding
Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH) Multisite Clinical Centers (Collaborative UG3/UH3 Clinical Trial Required)
Funding Opportunity RFA-HL-22-007 from the NIH Guide for Grants and Contracts. This FOA uses the bi-phasic, milestone-driven UG3/UH3 cooperative agreement mechanism (UG3/UH3), and runs in parallel with a companion FOA (RFA-HL-22-008), which seeks applications for a Data Coordinating Center (DCC). Awards made under this FOA will support a milestone-driven planning phase, including feasibility studies and pilot trials for up to 2 years, with possible transition to an implementation phase (UH3) for up to five additional years. Only UG3 trials that meet the scientific milestones and award requirements of the UG3 phase may t...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 22, 2021 Category: Research Source Type: funding
NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics (R33 Clinical Trial Required)
The objective of this funding opportunity is to support investigator-initiated, phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders in adults and children. The proposed trial can be single or multisite. Applicants applying for funding under this FOA should be ready to initiate the clinical trial within the first quarter of the project period. Discussion, submission, and attainment of applicable regulatory (FDA, DSMB, IRB) approvals, and establishment of drug (and placebo, if applicable) supplies, and any necessary third-party agreements should be establish...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 15, 2021 Category: Research Source Type: funding
NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics (R61/R33 Clinical Trial Required)
The objective of this funding opportunity is to support investigator-initiated, Phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders in adults and children. In addition to supporting clinical trial start-up and implementation activities, this FOA will provide support for final stage preclinical activities needed for the implementation of the proposed trial. All the activities proposed in the R61 phase must be directly related to the therapeutic/diagnostic in preparation for the clinical trial. The proposed trial can be single or multisite. This FOA will uti...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 15, 2021 Category: Research Source Type: funding
Understanding and Reducing Cardiovascular Disease in Type 1 Diabetes Mellitus (R01 Clinical Trial Optional)
Funding Opportunity RFA-HL-21-014 from the NIH Guide for Grants and Contracts. The goal of this funding opportunity is to support research that enhances the understanding of the pathophysiology and epidemiology of cardiovascular disease (CVD) among individuals with Type 1 Diabetes Mellitus (T1DM), and support the development of interventions to reduce CVD risk among these individuals. The overall goal is to develop evidence-based guidelines to prevent or reduce CVD complications of T1DM across the lifespan. This funding opportunity will support epidemiologic studies to refine risk assessment, mechanistic studies to enha...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 6, 2021 Category: Research Source Type: funding
NHLBI Program Project Applications (P01 Clinical Trials Optional)
Funding Opportunity PAR-21-088 from the NIH Guide for Grants and Contracts. The National Heart, Lung, and Blood Institute (NHLBI) Program Project Grant (P01) supports research related to fundamental processes and diseases of the heart, blood and lymphatic vessels, lungs, and blood, including transfusion medicine, blood resources, and sleep disorders other programs including implementation science, health disparities, and translation research that address the mission of the Institute. This FOA requires a minimum of three interrelated research projects that investigate a complex biomedical theme or research question. The ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - December 2, 2020 Category: Research Source Type: funding
Notice of NINR Participation in NOT-HL-20-737 Notice of Special Interest (NOSI): Palliative Care in Heart, Lung, Blood, and Sleep Diseases
Notice NOT-NR-20-007 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 12, 2020 Category: Research Source Type: funding
Notice of Intent to Publish a Funding Opportunity Announcement for Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH) Multisite (UG3/UH3) with Coordinating Center (U24)
Notice NOT-HL-20-820 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 27, 2020 Category: Research Source Type: funding
Notice of Special Interest (NOSI): Use of Predictive Analytics to Accelerate Late-Stage Implementation Research to Address Heart, Lung, Blood, and Sleep Disorders
Notice NOT-HL-20-815 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 26, 2020 Category: Research Source Type: funding
Notice of Change of Receipt Date for RFA-HL-21-016 "HeartShare: Next Generation Phenomics to Define Heart Failure Subtypes and Treatment Targets Data Translation Center (U54 Clinical Trial Not Allowed)"
Notice NOT-HL-20-822 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 22, 2020 Category: Research Source Type: funding
Notice of Change of Receipt Date for RFA-HL-21-015 "HeartShare: Next-Generation Phenomics to Define Heart Failure Subtypes and Treatment Targets Clinical Centers (U01 Clinical Trial Not Allowed)"
Notice NOT-HL-20-821 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 22, 2020 Category: Research Source Type: funding
Multidisciplinary Approaches to HIV-Associated Comorbidities and Prioritizing Intervention Targets (R01 Clinical Trial Not Allowed)
Funding Opportunity PAR-21-027 from the NIH Guide for Grants and Contracts. Basic research in the area of HIV-associated comorbidities has generally focused on the analysis of a pathway or a potential mechanism that contributes to the development of a single, specific HIV-associated comorbidity or end-organ disease. However, evidence indicates that there could be shared biological mechanisms that underlie the development of certain comorbidities, especially in the context of HIV infection. Targeting these mechanisms may not only impact HIV-associated comorbidities, but also have an impact on HIV cure and help elucidate ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 30, 2020 Category: Research Source Type: funding
Using Syndemics to Understand HLBS Disease Emergence and Progression in People with HIV (PWH)(R01 Clinical Trial Not Allowed)
Funding Opportunity RFA-HL-21-018 from the NIH Guide for Grants and Contracts. This funding opportunity announcement solicits research project grant (R01) applications that propose to utilize a syndemics (synergistic epidemic) framework to elucidate the role that social, economic, environmental, behavioral, structural, psychological factors play in promoting the synergistic interactions and clustering of heart, lung, blood, and sleep (HLBS) comorbidities and multi-morbidities among people with HIV at the population level. The ultimate goal is to identify strategies that foster integrated and holistic approaches in the c...
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 24, 2020 Category: Research Source Type: funding
NHLBI Announces Availability of Frequently Asked Questions (FAQs) for RFA-HL-21-001 "Hybrid Effectiveness-Implementation Trials for Heart, Lung, Blood, and Sleep Diseases in the Inpatient Setting (U01 - Clinical Trials Required)"
Notice NOT-HL-20-817 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - September 24, 2020 Category: Research Source Type: funding
