Notice of Change to Application Instructions for RFA-HL-19-009 "Cardiothoracic Surgical Trials Network (CTSN) Linked Clinical Research Centers (UM1 Clinical Trail Not Allowed)"
Notice NOT-HL-18-634 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 1, 2018 Category: Research Source Type: funding
COPD Learn More Breathe Better Subcontracts
Subcontracts to provide education and programming to increase awareness and understanding of Chronic Obstructive Pulmonary Disease (COPD) as a serious lung disease and a leading cause of death and disability in the U.S. Geographic coverage: Nationwide -- National Heart, Lung, and Blood Institute, National Institutes of Health, U.S. Department of Health and Human Services (Source: Funding opportunities via the Rural Health Information Hub)
Source: Funding opportunities via the Rural Health Information Hub - May 25, 2018 Category: American Health Source Type: funding
Request for Information (RFI): Resources or Services to Enable Functional Interpretation of Sequence Variants of Heart, Lung, Blood, and Sleep Disorders
Notice NOT-HL-18-630 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 22, 2018 Category: Research Source Type: funding
Cardiothoracic Surgical Trials Network (CTSN) Linked Clinical Research Centers (UM1 Clinical Trial Not Allowed )
Funding Opportunity RFA-HL-19-009 from the NIH Guide for Grants and Contracts. The Funding Opportunity Announcement (FOA) invites applications from qualified institutions willing to participate with NHLBI in the Cardiothoracic Surgical Trials Network (CTSN) as Linked Clinical Research Centers (LCRCs). The LCRCs will: (1) conduct collaborative randomized controlled trials (RCTs) and studies that evaluate cross specialty team-based care, interventions and novel therapies in the context of cardiac surgery but with broader relevance to cardiology and neurology; (2) utilize these findings to improve patient outcomes, and inf...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 16, 2018 Category: Research Source Type: funding
Limited Competition: Cardiothoracic Surgical Trials Network (CTSN) Data Coordinating Center (U01 Clinical Trial Required)
Funding Opportunity RFA-HL-19-010 from the NIH Guide for Grants and Contracts. The limited Funding Opportunity Announcement (FOA) invites an application to support the Data Coordinating Center (DCC) for the Cardiothoracic Surgical Trials Network (CTSN). A separate FOA (RFA-HL-19-009) seeks applications for Linked Clinical Research Centers (LCRCs). The goals of the CTSN renewal are to: (1) conduct collaborative randomized controlled trials (RCTs) and studies that evaluate cross specialty team-based care, interventions and novel therapies in the context of cardiac surgery but with broader relevance to cardiology and neuro...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 16, 2018 Category: Research Source Type: funding
Notice of NCATS Participation in RFA-HL-19-018 NHLBI SBIR Phase IIB Small Market Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 - Clinical Trial Optional)
Notice NOT-TR-18-026 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 16, 2018 Category: Research Source Type: funding
NHLBI SBIR Phase IIB Bridge Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 - Clinical Trial Optional)
Funding Opportunity RFA-HL-19-017 from the NIH Guide for Grants and Contracts. The purpose of the NHLBI SBIR Phase IIB Bridge Award is to facilitate and accelerate the capital-intensive steps that are required to transition SBIR/STTR Phase II projects to the commercialization stage by promoting partnerships between SBIR/STTR Phase II awardees and third-party investors and/or strategic partners. Applicants must submit a Commercialization Plan, which should include details on any independent third-party funding that has already been secured or is anticipated during the Phase IIB Bridge Award project period. It is expected...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 16, 2018 Category: Research Source Type: funding
NHLBI SBIR Phase IIB Small Market Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional)
Funding Opportunity RFA-HL-19-018 from the NIH Guide for Grants and Contracts. The purpose of the NHLBI SBIR Phase IIB Small Market Award is to provide support to Phase II SBIR or STTR awardees that are developing NHLBI mission-related products that address a rare disease or young pediatric populations. The goal of this FOA is for these products to be further validated so that development can continue with private funding after NHLBI support ends. Applicants must submit a Commercialization Plan that includes details on any independent third-party funding that has already been secured or is anticipated during the project...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 16, 2018 Category: Research Source Type: funding
High Obesity Program
Funding for land grant college and university projects designed to improve physical activity and nutrition; reduce obesity; and prevent and control diabetes, heart disease, and stroke in areas where adult obesity rates are above 40%. Geographic coverage: Available to serve specific counties in 17 states. -- Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion (Source: Funding opportunities via the Rural Health Information Hub)
Source: Funding opportunities via the Rural Health Information Hub - May 15, 2018 Category: American Health Source Type: funding
The Mechanistic Role of the Microbiome in the Pathobiology of Heart, Lung, Blood, and Sleep Diseases (R01 - Clinical Trial Not Allowed)
Funding Opportunity PA-18-784 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to support functional microbiome research focused on understanding the molecular, immunological and physiological mechanisms by which the microbiota (gut, lung, oral, including bacteria, viral and fungal microflora) and its derived factors modulate heart, lung, blood and sleep (HLBS) biology and physiology to promote health or contribute to disease. This FOA encourages mechanistic studies using in vitro, in vivo and/or ex vivo models that focus on the mechanistic and functional involve...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 15, 2018 Category: Research Source Type: funding
Catalyzing Innovation in Late Phase Clinical Trial Design and Statistical Analysis Plans (U34 Clinical Trial Not Allowed)
Funding Opportunity RFA-HL-19-027 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to provide support for planning activities for late phase (phase II and beyond) single-site or multi-site investigator-initiated clinical trials that address critical clinical questions within the mission of the National Heart, Lung, and Blood Institute (NHLBI) and that require non-traditional clinical trial designs with the opportunity for statistical novelty and/or innovation. The FOA will support the development of feasible and well-designed clinical trials utilizing consultative services provided by the Innovati...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 3, 2018 Category: Research Source Type: funding
Catalyzing Innovation in Late Phase Clinical Trial Design and Statistical Analysis Plans Resource Access (X01 Clinical Trial Not Allowed)
Funding Opportunity PAR-18-768 from the NIH Guide for Grants and Contracts. The purpose of this FOA is to provide access to a consultative resource for planning activities for late phase (phase II and beyond) single-site or multi-site investigator-initiated clinical trials that address critical clinical questions within the mission of the National Heart, Lung, and Blood Institute (NHLBI) and that require non-traditional clinical trial designs with the opportunity for statistical novelty and/or innovation. The FOA will support the development of feasible and well-designed clinical trials utilizing consultative services p...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 3, 2018 Category: Research Source Type: funding
Open Mike Perspective: Healthy Skepticism when Focusing Solely on Surrogate Endpoints in Clinical Research
I recently wrote an essay for the NIH’s Science, Health, and Public Trust series to encourage a healthy bit of skepticism about clinical studies that solely involve surrogate end-points (e.g. changes in “biomarkers” like blood cholesterol levels or findings on an electrocardiogram).
To make my point, I described experiences with a well-known cardiovascular trial — one that focused on the risk of sudden death among heart attack survivors. I encourage readers in this essay to not just assume that treating a surrogate endpoint will automatically treat the underlying condition. Sometimes it does. But sometimes it...
Source: NIH Extramural Nexus - May 3, 2018 Category: Research Authors: Mike Lauer Tags: blog Open Mike Clinical Trials innovation Perspectives Source Type: funding
Notice of Application Form Issue for PAR-16-021 "NHLBI TOPMed: Omics Phenotypes of Heart, Lung, and Blood Disorders (X01)"
Notice NOT-HL-18-627 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 30, 2018 Category: Research Source Type: funding
Notice of NIBIB's Participation in RFA-HL-19-016 "Technologies for Healthy Independent Living for Heart, Lung, Blood and Sleep Disorders (R43 Clinical Trial Not Allowed)"
Notice NOT-EB-18-015 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 30, 2018 Category: Research Source Type: funding
