What to do with BRAF-mutant melanoma patients who have a poor prognosis?
Grant McArthur, MBBS, BMedSci, PhD, FRACP, of the Peter MacCallum Cancer Centre, Melbourne, Australia, suggests next steps for poor prognosis BRAF-mutant melanoma patients with elevated lactate dehydr... Author: VJOncology Added: 10/06/2016 (Source: Oncology Tube)
Source: Oncology Tube - October 6, 2016 Category: Cancer & Oncology Source Type: podcasts

TWiV 409: A Nef is enough
Hosts:  Vincent Racaniello,  Dickson Despommier,  Alan Dove,  Rich Condit, and  Kathy SpindlerGuest:  Jeremy LubanJeremy joins the TWiVeroids to tell the amazing story of how the function of the HIV-1 protein called Nef was discovered  and found to promote infection by excluding the host protein SERINC from virus particles. Become a  patron of TWiV!Links for this episodeNo recovery in PACE trial (virology blog)The  real PACE data (virology blog)Contagious ThinkingFlorida DOH  daily Zika updateCongress  does not fail  on Zika (NPR)Nef history (Luban lab)Nef excludes SERINC from virions (Nature)SERINC  ...
Source: This Week in Virology - MP3 Edition - October 2, 2016 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Using biomarkers to predict response to combination therapies in BRAF-mutant melanoma
Grant McArthur, MBBS, BMedSci, PhD, FRACP, of the Peter MacCallum Cancer Centre, Melbourne, Australia, discusses the two currently approved combination therapies used for treating BRAF-mutant melanoma... Author: VJOncology Added: 09/27/2016 (Source: Oncology Tube)
Source: Oncology Tube - September 27, 2016 Category: Cancer & Oncology Source Type: podcasts

The developments of genetic testing and personalized cancer vaccines for patients with skin cancer
Grant McArthur, MBBS, BMedSci, PhD, FRACP, of the Peter MacCallum Cancer Centre, Melbourne, Australia, discusses the ways genetic testing is being carried out to date. First of all, there are some ver... Author: VJOncology Added: 09/21/2016 (Source: Oncology Tube)
Source: Oncology Tube - September 21, 2016 Category: Cancer & Oncology Source Type: podcasts

Targeting RAS oncogenes in patients with NRAS-mutated melanoma
Grant McArthur, MBBS, BMedSci, PhD, FRACP from the Peter MacCallum Cancer Centre, Melbourne, Australia gives an overview of mutations in melanoma and developments in therapies to combat such mutations... Author: VJOncology Added: 08/11/2016 (Source: Oncology Tube)
Source: Oncology Tube - August 11, 2016 Category: Cancer & Oncology Source Type: podcasts

Overall survival rates and prognostic categories for BRAF-mutated melanoma when treated with combination therapy
Grant McArthur, MBBS, BMedSci, PhD, FRACP from the Peter MacCallum Cancer Centre, Melbourne, Australia discusses the results of the Phase III coBRIM trial (NCT01689519), which focuses on therapies for... Author: VJOncology Added: 08/11/2016 (Source: Oncology Tube)
Source: Oncology Tube - August 11, 2016 Category: Cancer & Oncology Source Type: podcasts

TWiV 386: The dolphins did it
Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Guests: Ted Diehl and Welkin Johnson Ted and Welkin inform the TWiV team how the evolution of ancient retroviruses can be inferred by studying their sequences in the genomes of modern mammals, and join in a discussion of virus dispersal during different methods for drying hands.   Links for this episode More fun than a monkey full of viruses (TWiV 122) Tracking ancient retrovirus evolution in mammals (eLife) Virus dispersal during hand drying (J Appl Micro) More than you wanted to know about hand drying (one, two, three, four, five, six) This e...
Source: This Week in Virology - MP3 Edition - April 24, 2016 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Practicing deliberately for excellence
Malcolm Gladwell had popularized the ‘10,000 hour’ rule to expertise in his popular book ‘Outliers’. As per his formulation, anyone who puts in 10,000 hours of effort could excel in a particular field. What one required was determination and raw effort. He had based these conclusions on the work of Anders Ericsson and colleagues and now Anders Ericsson (with Robert Pool) in his new book ‘Peak’ has tried to clear the muddied waters surrounding the 10,000 hour rule. You can read an excerpt from peak here , where Anders himself clarifies that it doesn’t necessarily take 10,000 hours t...
Source: The Mouse Trap - April 23, 2016 Category: Psychiatry & Psychology Authors: sandygautam Tags: intelligence deliberate practice exprtise Source Type: podcasts

TWiV 384: Agent 003, a view to a fish kill
Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove and Rich Condit Guests: Nischay Mishra and Ian Lipkin Nischay and Ian join the TWiVions to discuss mass die-offs of tilapia by a novel orthomyxo-like virus, Ian's editorial on the movie Vaxxed, and new vaccines to prevent dengue virus infections, including a human challenge model.    Links for this episode Novel orthomyxo-like virus in Tilapia die-offs (mBio) Fish flu (TWiV 41) Anti-vaccination lunacy won't stop (WSJ) Single-dose dengue vaccine effective (J Inf Dis) Dengue vaccine needs (J Inf Dis) Composition of TV003 (J Inf Dis) Dengue vaccine mutagenesis ...
Source: This Week in Virology - MP3 Edition - April 10, 2016 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

February 9 2016 Issue
1) Mid-life milk consumption and substantia nigra neuron density at death2) What's Trending: Interview with Dr. Ray Dorsey about new Neurology site, which will be called Innovations in Care Delivery3) Topic of the month: Neurology Today story about should there be a moratorium on human germline editingThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Binit Shah interviews Dr. Robert Abbott about his paper on mid-life milk consumption and substantia nigra neuro density at death....
Source: Neurology Podcast - February 8, 2016 Category: Neurology Authors: American Academy of Neurology Source Type: podcasts

February 9 2016 Issue
1) Mid-life milk consumption and substantia nigra neuron density at death2) What's Trending: Interview with Dr. Ray Dorsey about new Neurology site, which will be called Innovations in Care Delivery3) Topic of the month: Neurology Today story about should there be a moratorium on human germline editingThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Binit Shah interviews Dr. Robert Abbott about his paper on mid-life milk consumption and substantia nigra neuro density at death....
Source: Neurology Podcast - February 8, 2016 Category: Neurology Authors: American Academy of Neurology Source Type: podcasts

TWiV 375: Zika and you will find
Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Guests: Carolyn Coyne, Helen Lazear, and Jeremy Luban The TWiVziks present everything you want to know about Zika virus, including association of infection with microcephaly and Guillain-Barré syndrome, transmission, epidemiology, and much more.   Links for this episode Zika outbreak in Brazil (EID) 13:40 Zika summary (ProMedMail) 19:30 Zika and microcephaly (MMWR) 27:30 Facts about microcephaly (CDC) Brazil Ministry of Health microcephaly numbers Zika spread in Americas (MMWR) Deu Zica 42:30 Microcephaly in Brazil (Lancet) 46:10 ...
Source: This Week in Virology - MP3 Edition - February 7, 2016 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

February 2 2016 Issue
1) Orthostatic tremor: Clinical, electrophysiologic and treatment findings in 184 patients2) What's Trending: Interview with Dr. Gretchen Birbeck about Global Neurology site, which will be called Without Borders3) Topic of the month: Neurology Today story about the SPRINT trial and lowering of blood pressure and strokeThis podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Jeff Ratliff interviews Dr. Anhar Hassan about her paper on the clinical, electrophysiologic and treatment findi...
Source: Neurology Podcast - February 1, 2016 Category: Neurology Authors: American Academy of Neurology Source Type: podcasts