Gastrointestinal stromal tumour in a jejunal diverticulum: The eighth reported case worldwide with a brief review of the literature
Malays J Pathol. 2023 Dec;45(3):473-478.ABSTRACTJejunal diverticulosis is uncommon and so are gastrointestinal stromal tumours (GIST) arising in the jejunum. GIST arising in a jejunal diverticulum is a rarity and to date there are only 7 cases in the English literature. Our case of GIST occurring in a jejunal diverticulum of a 48-year-old lady would be the first reported in Malaysia and the 8th in the world. As in most cases, the clinical presentation and radiological findings of this patient were non-specific. With a history of acute abdominal pain, vomiting and fever, the patient was provisionally diagnosed as a case of ...
Source: Malaysian Journal of Pathology - December 28, 2023 Category: Pathology Authors: S F Chiew Y F Toh L M Looi P L Cheah Source Type: research
Development of a simultaneous quantification method of imatinib and sunitinib and their main metabolites and its application in patients with gastrointestinal stromal tumor
Biomed Chromatogr. 2023 Dec 28:e5804. doi: 10.1002/bmc.5804. Online ahead of print.ABSTRACTCorrelations between plasma concentrations of imatinib and sunitinib with efficacy and toxicity have been established. It is crucial to develop a sensitive and precise method for determining the plasma concentrations of imatinib and sunitinib, along with their active metabolites, to facilitate therapeutic drug monitoring and individualized therapy. Plasma samples were separated on an Agilent ZORBAX SB-C18 chromatographic column using gradient elution. Quantification was performed using a mass spectrometer equipped with electrospray i...
Source: Biomedical Chromatography : BMC - December 28, 2023 Category: Biomedical Science Authors: Hefen Chen Jianbo Lyu Zhujun Gong Yong Han Kaixiong Tao Hong Zhou Source Type: research
Design, Synthesis, Characterisation, and Evaluation of Substituted Quinolin-2-one Derivatives as Possible Anti-lung Cancer Agents
CONCLUSION: Compound VII a showed the highest MolDock score and was most potent against human lung cancer cell line Hop-62.PMID:38151847 | DOI:10.2174/0115701638258479231220051227 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - December 28, 2023 Category: Drugs & Pharmacology Authors: Riya Swar Prachita Gauns Dessai Shivalingrao MamleDesai Sachin Chandavarkar Soniya Phadte B Biradar Source Type: research
Gastrointestinal stromal tumour in a jejunal diverticulum: The eighth reported case worldwide with a brief review of the literature
Malays J Pathol. 2023 Dec;45(3):473-478.ABSTRACTJejunal diverticulosis is uncommon and so are gastrointestinal stromal tumours (GIST) arising in the jejunum. GIST arising in a jejunal diverticulum is a rarity and to date there are only 7 cases in the English literature. Our case of GIST occurring in a jejunal diverticulum of a 48-year-old lady would be the first reported in Malaysia and the 8th in the world. As in most cases, the clinical presentation and radiological findings of this patient were non-specific. With a history of acute abdominal pain, vomiting and fever, the patient was provisionally diagnosed as a case of ...
Source: Malaysian Journal of Pathology - December 28, 2023 Category: Pathology Authors: S F Chiew Y F Toh L M Looi P L Cheah Source Type: research
Development of a simultaneous quantification method of imatinib and sunitinib and their main metabolites and its application in patients with gastrointestinal stromal tumor
Biomed Chromatogr. 2023 Dec 28:e5804. doi: 10.1002/bmc.5804. Online ahead of print.ABSTRACTCorrelations between plasma concentrations of imatinib and sunitinib with efficacy and toxicity have been established. It is crucial to develop a sensitive and precise method for determining the plasma concentrations of imatinib and sunitinib, along with their active metabolites, to facilitate therapeutic drug monitoring and individualized therapy. Plasma samples were separated on an Agilent ZORBAX SB-C18 chromatographic column using gradient elution. Quantification was performed using a mass spectrometer equipped with electrospray i...
Source: Biomedical Chromatography : BMC - December 28, 2023 Category: Biomedical Science Authors: Hefen Chen Jianbo Lyu Zhujun Gong Yong Han Kaixiong Tao Hong Zhou Source Type: research
Design, Synthesis, Characterisation, and Evaluation of Substituted Quinolin-2-one Derivatives as Possible Anti-lung Cancer Agents
CONCLUSION: Compound VII a showed the highest MolDock score and was most potent against human lung cancer cell line Hop-62.PMID:38151847 | DOI:10.2174/0115701638258479231220051227 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - December 28, 2023 Category: Drugs & Pharmacology Authors: Riya Swar Prachita Gauns Dessai Shivalingrao MamleDesai Sachin Chandavarkar Soniya Phadte B Biradar Source Type: research
Gastrointestinal stromal tumour in a jejunal diverticulum: The eighth reported case worldwide with a brief review of the literature
Malays J Pathol. 2023 Dec;45(3):473-478.ABSTRACTJejunal diverticulosis is uncommon and so are gastrointestinal stromal tumours (GIST) arising in the jejunum. GIST arising in a jejunal diverticulum is a rarity and to date there are only 7 cases in the English literature. Our case of GIST occurring in a jejunal diverticulum of a 48-year-old lady would be the first reported in Malaysia and the 8th in the world. As in most cases, the clinical presentation and radiological findings of this patient were non-specific. With a history of acute abdominal pain, vomiting and fever, the patient was provisionally diagnosed as a case of ...
Source: Malaysian Journal of Pathology - December 28, 2023 Category: Pathology Authors: S F Chiew Y F Toh L M Looi P L Cheah Source Type: research
Design, Synthesis, Characterisation, and Evaluation of Substituted Quinolin-2-one Derivatives as Possible Anti-lung Cancer Agents
CONCLUSION: Compound VII a showed the highest MolDock score and was most potent against human lung cancer cell line Hop-62.PMID:38151847 | DOI:10.2174/0115701638258479231220051227 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - December 28, 2023 Category: Drugs & Pharmacology Authors: Riya Swar Prachita Gauns Dessai Shivalingrao MamleDesai Sachin Chandavarkar Soniya Phadte B Biradar Source Type: research
Gastrointestinal stromal tumour in a jejunal diverticulum: The eighth reported case worldwide with a brief review of the literature
Malays J Pathol. 2023 Dec;45(3):473-478.ABSTRACTJejunal diverticulosis is uncommon and so are gastrointestinal stromal tumours (GIST) arising in the jejunum. GIST arising in a jejunal diverticulum is a rarity and to date there are only 7 cases in the English literature. Our case of GIST occurring in a jejunal diverticulum of a 48-year-old lady would be the first reported in Malaysia and the 8th in the world. As in most cases, the clinical presentation and radiological findings of this patient were non-specific. With a history of acute abdominal pain, vomiting and fever, the patient was provisionally diagnosed as a case of ...
Source: Malaysian Journal of Pathology - December 28, 2023 Category: Pathology Authors: S F Chiew Y F Toh L M Looi P L Cheah Source Type: research
Design, Synthesis, Characterisation, and Evaluation of Substituted Quinolin-2-one Derivatives as Possible Anti-lung Cancer Agents
CONCLUSION: Compound VII a showed the highest MolDock score and was most potent against human lung cancer cell line Hop-62.PMID:38151847 | DOI:10.2174/0115701638258479231220051227 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - December 28, 2023 Category: Drugs & Pharmacology Authors: Riya Swar Prachita Gauns Dessai Shivalingrao MamleDesai Sachin Chandavarkar Soniya Phadte B Biradar Source Type: research
Gastrointestinal stromal tumour in a jejunal diverticulum: The eighth reported case worldwide with a brief review of the literature
Malays J Pathol. 2023 Dec;45(3):473-478.ABSTRACTJejunal diverticulosis is uncommon and so are gastrointestinal stromal tumours (GIST) arising in the jejunum. GIST arising in a jejunal diverticulum is a rarity and to date there are only 7 cases in the English literature. Our case of GIST occurring in a jejunal diverticulum of a 48-year-old lady would be the first reported in Malaysia and the 8th in the world. As in most cases, the clinical presentation and radiological findings of this patient were non-specific. With a history of acute abdominal pain, vomiting and fever, the patient was provisionally diagnosed as a case of ...
Source: Malaysian Journal of Pathology - December 28, 2023 Category: Pathology Authors: S F Chiew Y F Toh L M Looi P L Cheah Source Type: research
Design, Synthesis, Characterisation, and Evaluation of Substituted Quinolin-2-one Derivatives as Possible Anti-lung Cancer Agents
CONCLUSION: Compound VII a showed the highest MolDock score and was most potent against human lung cancer cell line Hop-62.PMID:38151847 | DOI:10.2174/0115701638258479231220051227 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - December 28, 2023 Category: Drugs & Pharmacology Authors: Riya Swar Prachita Gauns Dessai Shivalingrao MamleDesai Sachin Chandavarkar Soniya Phadte B Biradar Source Type: research
Gastrointestinal stromal tumour in a jejunal diverticulum: The eighth reported case worldwide with a brief review of the literature
Malays J Pathol. 2023 Dec;45(3):473-478.ABSTRACTJejunal diverticulosis is uncommon and so are gastrointestinal stromal tumours (GIST) arising in the jejunum. GIST arising in a jejunal diverticulum is a rarity and to date there are only 7 cases in the English literature. Our case of GIST occurring in a jejunal diverticulum of a 48-year-old lady would be the first reported in Malaysia and the 8th in the world. As in most cases, the clinical presentation and radiological findings of this patient were non-specific. With a history of acute abdominal pain, vomiting and fever, the patient was provisionally diagnosed as a case of ...
Source: Malaysian Journal of Pathology - December 28, 2023 Category: Pathology Authors: S F Chiew Y F Toh L M Looi P L Cheah Source Type: research
Design, Synthesis, Characterisation, and Evaluation of Substituted Quinolin-2-one Derivatives as Possible Anti-lung Cancer Agents
CONCLUSION: Compound VII a showed the highest MolDock score and was most potent against human lung cancer cell line Hop-62.PMID:38151847 | DOI:10.2174/0115701638258479231220051227 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - December 28, 2023 Category: Drugs & Pharmacology Authors: Riya Swar Prachita Gauns Dessai Shivalingrao MamleDesai Sachin Chandavarkar Soniya Phadte B Biradar Source Type: research
Gastrointestinal stromal tumour in a jejunal diverticulum: The eighth reported case worldwide with a brief review of the literature
Malays J Pathol. 2023 Dec;45(3):473-478.ABSTRACTJejunal diverticulosis is uncommon and so are gastrointestinal stromal tumours (GIST) arising in the jejunum. GIST arising in a jejunal diverticulum is a rarity and to date there are only 7 cases in the English literature. Our case of GIST occurring in a jejunal diverticulum of a 48-year-old lady would be the first reported in Malaysia and the 8th in the world. As in most cases, the clinical presentation and radiological findings of this patient were non-specific. With a history of acute abdominal pain, vomiting and fever, the patient was provisionally diagnosed as a case of ...
Source: Malaysian Journal of Pathology - December 28, 2023 Category: Pathology Authors: S F Chiew Y F Toh L M Looi P L Cheah Source Type: research
