The effectiveness of telehealth gait retraining in addition to standard physical therapy treatment for overuse knee injuries in soldiers: a protocol for a randomized clinical trial
DiscussionThe effectiveness of a telehealth gait retraining intervention to reduce pain and modify foot strike pattern is not known. The results of this study may help determine the effectiveness and feasibility of a telehealth gait retraining intervention to reduce pain, change foot strike, improve function, and improve running gait biomechanics.Trial registrationClinicalTrials.gov,NCT04269473. Registered 05 February 2020. (Source: Trials)
Source: Trials - October 16, 2023 Category: Research Source Type: clinical trials
Sleep Technology Intervention to Target Cardiometabolic Health (STITCH): a randomized controlled study of a behavioral sleep extension intervention compared to an education control to improve sleep duration, blood pressure, and cardiometabolic health among adults with elevated blood pressure/hypertension
DiscussionThe results of this study will determine the effects of behavioral sleep extension on sleep and cardiometabolic health among adults with short sleep duration and elevated BP/hypertension. The results will inform the feasibility and efficacy of behavioral sleep extension and provide information needed for future multi-site effectiveness studies.Trial registrationClinicalTrials.gov NCT04766424. Registered on 21 February 2021. (Source: Trials)
Source: Trials - October 10, 2023 Category: Research Source Type: clinical trials
Holistic Mixed Approaches to Capture the Real Life of Children With Rare Eye Diseases
Conditions: Eye Diseases; Severe Loss of Vision; Blindness; Quality of Life Interventions: Other: Mixed Methods Research (MMR) using quantitative (QUAN) and qualitative (QUAL) tools Sponsors: University Hospital, Strasbourg, France Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 6, 2023 Category: Research Source Type: clinical trials
Clinical Investigation of a New Version of MAIA Microperimeter on Healthy Subjects and Patients With Retinal Pathology
Conditions: Healthy Eyes; Retinal Diseases Interventions: Device: MAIA Sponsors: Centervue SpA Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 6, 2023 Category: Research Source Type: clinical trials
Virgin Coconut Oil Contact Lens as Ocular Rewetting Agent
Conditions: Dry Eyes Interventions: Other: organic product - Virgin Coconut Oil Sponsors: National University of Malaysia Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 6, 2023 Category: Research Source Type: clinical trials
Randomised controlled trial of the Community Navigator programme to reduce loneliness and depression for adults with treatment-resistant depression in secondary community mental health services: trial protocol
DiscussionThis trial will provide definitive evidence about the effectiveness and cost-effectiveness of the Community Navigator programme and whether it can be recommended for use in practice. The trial is due to finish in August 2025.Trial registrationProspectively registered on 8th July 2022 at: ISRCTN13205972. (Source: Trials)
Source: Trials - October 6, 2023 Category: Research Source Type: clinical trials
Testing the combination of Feeling Safe and peer counselling against formulation-based cognitive behaviour therapy to promote psychological wellbeing in people with persecutory delusions: study protocol for a randomized controlled trial (the Feeling Safe-NL Trial)
DiscussionThe Feeling Safe-NL Trial is the first to evaluate a treatment for people with persecutory delusions, while using mental wellbeing as the primary outcome. It will also provide the first evaluation of the combination of a peer counselling intervention and a CBT-based program for recovery from persecutory delusions.Trial registrationCurrent Controlled Trials ISRCTN25766661 (retrospectively registered 7 July 2022). (Source: Trials)
Source: Trials - October 5, 2023 Category: Research Source Type: clinical trials
Bedside Bone Biopsy in Diabetic Foot Osteomyelitis
Conditions: Subjects With Diabetes and DFU With a Suspicion of DFO Interventions: Procedure: Bedside blind bone biopsy procedure Sponsors: Assistance Publique - H ôpitaux de Paris Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 4, 2023 Category: Research Source Type: clinical trials
Preconditioning of the motor network with repetitive navigated transcranial magnetic stimulation (rnTMS) to improve oncological and functional outcome in brain tumor surgery: a study protocol for a randomized, sham-controlled, triple-blind clinical trial
DiscussionThe generated reorganization of the brain ’s areas for motor function should allow a more extensive and safer removal of the tumor while preserving neurological and motor function. This would improve both survival and quality of life of our patients.Trial registrationDRKS.deDRKS00017232. Registered on 28 January 2020. (Source: Trials)
Source: Trials - October 4, 2023 Category: Research Source Type: clinical trials
Outcome of Two Surgical Methods for IOLImplantation in Eyes With Pseudoexfoliation Syndrome
Conditions: Age Related Cataracts; Pseudoexfoliation Syndrome Interventions: Procedure: Phakoemulsification; Device: Ziemer Z8 Femtolaser; Device: Kowa Avansee Preset Sponsor: Medical University of Vienna Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 25, 2023 Category: Research Source Type: clinical trials
Outcome of Two Surgical Methods for IOLImplantation in Eyes With Pseudoexfoliation Syndrome
Conditions: Age Related Cataracts; Pseudoexfoliation Syndrome Interventions: Procedure: Phakoemulsification; Device: Ziemer Z8 Femtolaser; Device: Kowa Avansee Preset Sponsors: Medical University of Vienna Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 25, 2023 Category: Research Source Type: clinical trials
A monocenter, patient-blinded, randomized, parallel-group, non-inferiority study to compare cochlear implant receiver/stimulator device fixation techniques (COMFIT) with and without drilling in adults eligible for primary cochlear implantation
DiscussionCochlear implantation by means of creating a tight subperiosteal pocket without drilling a bony seat is a minimally invasive fixation technique with many advantages. However, the safety of this technique has not yet been proven with certainty. This is the first randomized controlled trial that directly compares the minimally invasive technique with the conventional method of drilling a bony seat.Trial registrationNetherlands Trial Register NL9698. Registered on 31 August 2021. (Source: Trials)
Source: Trials - September 24, 2023 Category: Research Source Type: clinical trials
