Safety Study of Enterovirus 71 Vaccine in Children Aged 6-35 Months Old
Condition: Enterovirus 71 VaccineIntervention: Biological: two doses enterovirus 71 vaccineSponsor: Beijing Chaoyang District Centre for Disease Control and PreventionNot yet recruiting - verified June 2016 (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 16, 2016 Category: Research Source Type: clinical trials
Intravenous magnesium sulfate for the management of severe hand, foot, and mouth disease with autonomic nervous system dysregulation in Vietnamese children: study protocol for a randomized controlled trial
We describe the protocol for a randomized, placebo-controlled, double-blind trial of intravenous MgSO4 in Vietnamese children diagnosed clinically with HFMD plus ANS dysregulation with systemic hypertension. A loading dose of MgSO4 or identical placebo is given over 20 min followed by a maintenance infusion for 72 h according to response, aiming for Mg levels two to three times the normal level in the treatment arm. The primary endpoint is a composite of disease progression within 72 h defined as follows: development of pre-specified blood pressure criteria necessitating the addition of milrinone, the need for ventilati...
Source: Trials - February 19, 2016 Category: Research Source Type: clinical trials
