Sugar-Coated Nanosheets Can Selectively Bind Pathogens
Researchers at the U.S. Department of Energy’s Lawrence Berkeley National Laboratory have developed sugar-coated ultrathin self-assembling nanosheets that can selectively bind to pathogens, and which have potential to serve as a diagnostic technology or a way to inactivate pathogens.
The researchers developed the structures using bioinspired synthetic polymers, known as peptoids, which can self-assemble to form ultrathin nanosheets. “The chemical information that instructs the molecules to spontaneously assemble into the sugar-coated sheets is programmed into each molecule during its synthesis,” said Ronald Zucke...
Source: Medgadget - April 3, 2018 Category: Medical Devices Authors: Conn Hastings Tags: Diagnostics Nanomedicine Public Health Source Type: blogs
Tropical Travel Trouble 006 Watery Diarrhoea
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
aka Tropical Travel Trouble 006
Our medical student who caught shigella on a Nepalese elective has a thirst for adventure. They plan to help at a Bangladesh refugee camp but the latest CDC report states there have been some cases of cholera. They’ve done a little bit of reading and want your help to teach them all about cholera and how they may prepare and best serve their new community.
Questions:
Q1. What is cholera and how is it transmitted?
Answer and interpreta...
Source: Life in the Fast Lane - March 27, 2018 Category: Emergency Medicine Authors: Neil Long Tags: Clinical Cases Tropical Medicine cholera diarrhoea john snow ORS rice water diarrhoea watery diarrhoea Source Type: blogs
Funtabulously Frivolous Friday Five 231
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia FFFF…introducing Funtabulously Frivolous Friday Five 231.
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Question 1:
You find yourself on holiday in Africa helping out with a dermatology clinic (yes, your forte as an emergency physician). In the queue is a young boy who describes a papular ...
Source: Life in the Fast Lane - March 22, 2018 Category: Emergency Medicine Authors: Neil Long Tags: Frivolous Friday Five anthrax cholera Dilip Mahalanabis Dr Bayford dysentery dysphagia lusoria ORS saber shins Thomas Hodgkin wool-sorters disease yaws Source Type: blogs
Tropical Travel Trouble 005 RUQ Pain and Jaundice
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
aka Tropical Travel Trouble 005
Guest Post: Dr Branden Skarpiak – Global Health Fellow, Department of Emergency Medicine. UT Health San Antonio
A 35 year old male presents to your emergency room for right upper quadrant pain that has gotten worse over the last 2-3 days. He also describes associated nausea, vomiting, and fevers. He denies other abdominal pain, or change in his bowel or bladder habits. His wife notes that he has started to “look more yellow” recent...
Source: Life in the Fast Lane - March 19, 2018 Category: Emergency Medicine Authors: Neil Long Tags: Clinical Cases Tropical Medicine amebic amoeba amoebiasis amoebic dysentery amoebic liver abscess bloody diarrhoea e.dispar e.histolytica entamoeba histolytica Source Type: blogs
Tropical Travel Trouble 004 Bloody Diarrhoea
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
aka Tropical Travel Trouble 004
A medical student who has just returned from their elective in Nepal presents with 1 week of bloody diarrhoea. He has been in the lowlands and stayed with a family in the local village he was helping at. It started three days before he left and he decided to get home on the plane in the hope it would settle. He is now opening his bowels 10x a day with associated cramps, fevers and has started feeling dizzy.
Questions:
Q1. What is dysentery ...
Source: Life in the Fast Lane - March 12, 2018 Category: Emergency Medicine Authors: Neil Long Tags: Clinical Cases Tropical Medicine amoebic dysentery bacillary dysentery e.histolytica entamoeba histolytica shigellosis Source Type: blogs
Got diarrhea? The latest trend in fashionable nonsense is “ raw water ”
In pseudoscience, appeals to nature are everywhere. It’s not surprising, then, that there is profit to be made selling “raw” (i.e., untreated) water at very high prices for its nonexistent health benefits, those benefits all claimed to be due to the “naturalness” of the water. I can’t help but note that cholera, Giardia, amoebic dysentery, and a wide variety of waterborne illnesses prevented by modern water treatment techniques are all very, very “natural."
The post Got diarrhea? The latest trend in fashionable nonsense is “raw water” appeared first on RESPECTFUL INSOLENCE. (Source: Respectful Insolence)
Source: Respectful Insolence - January 8, 2018 Category: Surgery Authors: Orac Tags: Medicine Pseudoscience Skepticism/critical thinking bacteria cholera diarrhea featured Giardia Live Water Mukhande Singh raw water Source Type: blogs
Should only infectious disease specialists be allowed to prescribe antibiotics?
The WHO’s recent announcement of multi-drug resistant strains of gonorrhea raises the specter of a worldwide SuperClap Attack that even the Avengers couldn’t foil. It also comes as yet another ominous reminder of the perils of rampant and indiscriminate antibiotic use.
There’s plenty of blame to spread around. True, here in the U.S., consumers can’t buy antibiotics over the counter, but that hasn’t kept physicians and other providers from over-prescribing them with a casual “more-is-more,” “just-in-case” philosophy. As an internist colleague once warned me, facetiously, with furrowed brow, “We’re seei...
Source: Kevin, M.D. - Medical Weblog - August 9, 2017 Category: General Medicine Authors: < a href="http://www.kevinmd.com/blog/post-author/craig-bowron" rel="tag" > Craig Bowron, MD < /a > Tags: Meds Hospital Hospitalist Infectious disease Medications Source Type: blogs
Cruelty and enlightenment
I don’t know if the following observations are profound or trite or somewhere in between. They are prompted by a recent visit to the Cascades Female Factory in Hobart, Tasmania.Every country, it seems, has something to be ashamed of in its history. Certainly, among other things, the US bears blame for its treatment of native Americans, slaves imported from Africa, and forced detention of Japanese descendants during World War II.And yet, those same countries have often made contributions to political systems that are truly noteworthy in the advancement of human society. Think of the principles espoused in the Mayflo...
Source: Not running a hospital - February 8, 2016 Category: Hospital Management Source Type: blogs
Shigella book available very soon
The new book on Shigella edited by William D. Picking and Wendy L. Picking will be available for dispatch within the next 2 or 3 weeks read more ...Shigella: Molecular and Cellular BiologyEdited by: William D. Picking and Wendy L. PickingCaister Academic PressPaperback: ISBN 978-1-910190-19-7 £159, $319. Ebook: ISBN 978-1-910190-20-3 £159, $319Up-to-date reviews of current knowledge and recent advances in the molecular biology of Shigella. read more ...Full information at Shigella. (Source: Microbiology Blog: The weblog for microbiologists.)
Source: Microbiology Blog: The weblog for microbiologists. - July 3, 2015 Category: Microbiology Source Type: blogs
Getting King John To Sign Magna Carta Was Only Half The Battle
The very day King John pledged to uphold Magna Carta, June 20, 1215, he asked Pope Innocent III to annul it. The pope replied, “We utterly reject and condemn this settlement and under threat of excommunication we order that the king should not dare to observe it and that the barons and their associates should not require it to be observed.”
So, John reneged on his agreement with the barons, they rebelled and formed an alliance with King Philip II of France who prepared to invade England. Before long, the French Prince Louis entered London, and the French controlled castles throughout England. The English Church, ...
Source: Cato-at-liberty - June 4, 2015 Category: American Health Authors: Jim Powell Source Type: blogs
Shigella
William D. Picking and Wendy L. Picking present a new book on Shigella: Molecular and Cellular Biology This book provides a thorough overview of current research on the cellular and molecular biology of Shigella. Expert authors have contributed authoritative and up-to-date reviews of current knowledge and recent advances in the molecular biology of these pathogens. The first section of the book explores aspects of metabolism and gene regulation and examines the molecular and cellular biology of Shigella as a genus diversified from Escherichia. This section also considers often overlooked features of bacterial pathogens and...
Source: Microbiology Blog: The weblog for microbiologists. - May 9, 2015 Category: Microbiology Source Type: blogs
Building Unity Farm - Winter Hive Maintenance
The 2014 winter has been brutal with more single degree days than any winter during my 20 years living in Massachusetts. Our bees are resilient, started from colonies overwintered in New Hampshire last year. Keeping them alive has required careful management and we’ve learned a great deal in our first year as beekeepers.We began the winter with 8 hives, 7 of which were strong and one of which had very few bees.Our hives started as “nucs” 5 frame mini hives purchased from an apiary. We placed the frames in 10 frame deep body boxes last May. After a few months, we added another layer of 10 fr...
Source: Life as a Healthcare CIO - March 13, 2014 Category: Technology Consultants Source Type: blogs
Answer to Case 244
Answer: Plant material, or as bks and zanarditos said "Not a parasite! Cell wall+outer coat make me think of a SEED!" I agree that this is most likely a seed, given its roughened outer coat and 2 internal structures which may represent seed leaves or "cotyledons." On higher magnification, you can see the characteristic rigid, geometrically shaped cells that are also characteristic of plant material: The differential diagnosis could include the small intestinal flukes such as Heterophyes heterophyes, given it's similar size and shape. However, the internal morphology is much different, and the presenc...
Source: Creepy Dreadful Wonderful Parasites - February 2, 2013 Category: Pathologists Source Type: blogs
Epidemiology Pathogenesis and Genetics of Diarrhoeagenic Escherichia coli Infections
Epidemiology, Pathogenesis and Genetics of Diarrhoeagenic Escherichia coli Infectionsfrom T. Ramamurthy and M. John Albert writing in Foodborne and Waterborne Bacterial Pathogens: Epidemiology, Evolution and Molecular Biology:There are five categories of diarrhoeagenic Escherichia coli (DEC) namely enterotoxigenic, enteropathogenic, enterohaemorrhagic, enteroinvasive and enteroaggregative. They have evolved from nonpathogenic commensal strains by acquisition of specific virulence genes through mobile genetic elements. Their pathogenesis differs and they produce distinct clinical syndromes and pathological lesions and have ...
Source: Microbiology Blog: The weblog for microbiologists. - January 4, 2013 Category: Microbiology Source Type: blogs
