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The epigenetic clock, biological age, and chronic diseases
NIH Director’s Wednesday Afternoon Lecture Series It has been a long standing goal to develop molecular biomarkers of biological age. Recent studies demonstrate that powerful epigenetic biomarkers of aging can be defined based on DNA methylation levels. For example, the epigenetic clock (PMID: 24138928) is a multivariate age estimation method that applies to sorted cell types (CD4T cells or neurons), complex tissues, and organs and even prenatal brain samples. The epigenetic clock is an attractive biomarker of aging because a) it applies to most human and chimpanzee tissues, b) its accurate measurement of chronological ...
Source: Videocast - All Events - May 31, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video