Fight Aging! Newsletter, September 11th 2023
This article reviews the current regulatory role of miR-7 in inflammation and related diseases, including viral infection, autoimmune hepatitis, inflammatory bowel disease, and encephalitis. It expounds on the molecular mechanism by which miR-7 regulates the occurrence of inflammatory diseases. Finally, the existing problems and future development directions of miR-7-based intervention on inflammation and related diseases are discussed to provide new references and help strengthen the understanding of the pathogenesis of inflammation and related diseases, as well as the development of new strategies for clinical interventi...
Source: Fight Aging! - September 10, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Beyond the Scale: How organizations should evaluate the success of obesity management solutions
Conclusion
Organizations have much to consider when evaluating obesity solutions for their population. It’s easy to be swayed by simple metrics that seem indisputable. But, in the end, outcomes like 5% weight loss and reductions in HbA1c for the majority of an eligible population are what counts. Sustainable outcomes rely on real behavior change, a careful step-therapy approach to medication, and personalized care when it comes to social determinants of health.
Caitlyn Edwards, PhD, RDN, is a Senior Clinical Research Specialist at Vida Health (Source: The Health Care Blog)
Source: The Health Care Blog - September 8, 2023 Category: Consumer Health News Authors: matthew holt Tags: Medical Practice Caitlyn Edwards GLP-1 Obesity SDoH vida health Source Type: blogs
Bumper Sticker installment for Labor Day
I ' m going to skip ahead on bumper sticker to match the occasion: " Capitalism lifts people up from poverty. "As usual, I ' m not sure exactly what the implication of this is supposed to be. In grand historical terms, it is true that human material well being has increased enormously since the advent of industrial capitalism in the 19th Century. That is the economic system that converted fossil fuel into the astonishing technological development and material infrastructure that distinguishes the modern world from all of previous history. But it doesn ' t seem to be much of a political point. Nobody on the left ...
Source: Stayin' Alive - September 4, 2023 Category: American Health Source Type: blogs
The Cost of Cardiovascular Disease
Age-related disease places a huge financial burden on individuals and their caregivers; even the need for caregivers arises only because aging produces disability. Even only considering cardiovascular disease, the largest contribution to human mortality, the costs are enormous. This is a point often made by advocates arguing for greater institutional funding of ways to treat aging. Present levels of funding for research and development of means to reduce age-related disease are very low in comparison to the massive ongoing costs that result from age-related disease. It makes little sense for this to be the case in an age o...
Source: Fight Aging! - September 4, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Dancing around the hexaflex: Using ACT in practice 3
Acceptance and commitment therapy (ACT) can be slippery to describe. It’s an approach that doesn’t aim to change thought content, but instead to help us shift the way we relate to what our mind tells us. It’s also an approach focused on workability: pragmatic and context-specific analysis of how well a strategy is working to achieve being able to do what matters. Over the next few posts I want to give some examples of how non-psychologists can use ACT in session (remember ACT is open for anyone to use it!).
Cognitive defusion
I’m guessing that for psychologists and those who primarily work wit...
Source: HealthSkills Weblog - September 4, 2023 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: ACT - Acceptance & Commitment Therapy Chronic pain Clinical reasoning Coping strategies Occupational therapy Pain conditions Physiotherapy Psychology Science in practice acceptance and commitment therapy cognitive fusion pain managem Source Type: blogs
Fight Aging! Newsletter, September 4th 2023
In conclusion, although the contribution of CRF to GrimAgeAccel and FitAgeAccel is relatively low compared to lifestyle-related factors such as smoking, the results suggest that the maintenance of CRF is associated with delayed biological ageing in older men.
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Release of Acetylcholine is Necessary for the Aging Brain to Compensate for a Lack of Neurogenesis
https://www.fightaging.org/archives/2023/09/release-of-acetylcholine-is-necessary-for-the-aging-brain-to-compensate-for-a-lack-of-neurogenesis/
Neurogenesis is the process by which new neurons are created by neural stem c...
Source: Fight Aging! - September 3, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Release of Acetylcholine is Necessary for the Aging Brain to Compensate for a Lack of Neurogenesis
We examined whether adult neurogenesis sustains hippocampal connections cumulatively across the life span. Long-term suppression of neurogenesis as occurs during stress and aging resulted in an accelerated decline in hippocampal acetylcholine signaling and a slow and progressing emergence of profound working memory deficits.
These deficits were accompanied by compensatory reorganization of cholinergic dentate gyrus inputs with increased cholinergic innervation to the ventral hippocampus and recruitment of ventrally projecting neurons by the dorsal projection. While increased cholinergic innervation was dysfunctional...
Source: Fight Aging! - September 1, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
The Long Legacy of COVID-19 Disability
Jon L. Gelman (Jon L Gelman LLC), The Long Legacy of COVID-19 Disability (2023): The legacy of the COVID-19 pandemic persists. There exists a continuing need for long-term treatment and disability. While state benefit systems such as workers ’ compensation have... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - September 1, 2023 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs
The Lonely Epidemic: Social Isolation and Technology
Alarming effects have been found from recent digital technologies on social connections and mental health. The Surgeon General issued a highly publicized advisory on loneliness and another on youth, both replete with evidence of the harm done by social media and the internet generally. But can digital technology also improve social connections?
While the harm done by digital media to many people has been well demonstrated, there are also people who thrive on digital connections, particularly people from marginalized groups who have trouble finding each other in physical settings). The Surgeon General advisory on youth poin...
Source: EMR and HIPAA - August 29, 2023 Category: Information Technology Authors: Andy Oram Tags: Clinical Health IT Company LTPAC Caretakers Catalaize Dor Skuler Healthcare Isolation Healthcare Loneliness Healthcare Social Media Intuition Robotics mental health Sara Shanti Sheppard Mullin social isolation UCLA UCLA Lonel Source Type: blogs
Dancing around the hexaflex: Using ACT in practice 2
Acceptance and commitment therapy (ACT) can be slippery to describe. It’s an approach that doesn’t aim to change thought content, but instead to help us shift the way we relate to what our mind tells us. It’s also an approach focused on workability: pragmatic and context-specific analysis of how well a strategy is working to achieve being able to do what matters. Over the next few posts I want to give some examples of how non-psychologists (remember ACT is open for anyone to use it!) can use ACT in session.
Self as context
From my experience, this process is possibly the least well understood of the ACT hexafle...
Source: HealthSkills Weblog - August 27, 2023 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: ACT - Acceptance & Commitment Therapy Chronic pain Coping strategies Pain conditions Professional topics Science in practice acceptance and commitment therapy Clinical reasoning Occupational therapy Therapeutic approaches Source Type: blogs
Dancing around the hexaflex: Using ACT in practice 2
Acceptance and commitment therapy (ACT) can be slippery to describe. It’s an approach that doesn’t aim to change thought content, but instead to help us shift the way we relate to what our mind tells us. It’s also an approach focused on workability: pragmatic and context-specific analysis of how well a strategy is working to achieve being able to do what matters. Over the next few posts I want to give some examples of how non-psychologists (remember ACT is open for anyone to use it!) can use ACT in session.
Self as context
From my experience, this process is possibly the least well understood of the ACT hexafle...
Source: HealthSkills Weblog - August 27, 2023 Category: Anesthesiology Authors: BronnieLennoxThompson Tags: ACT - Acceptance & Commitment Therapy Chronic pain Coping strategies Pain conditions Professional topics Science in practice acceptance and commitment therapy Clinical reasoning Occupational therapy Therapeutic approaches Source Type: blogs
The Importance of Patient Portal Usability
The following is a guest article by Dr. Bruce Bassi, Advisory Board Member at CharmHealth
Most patients have almost certainly received an invitation to join their electronic medical record communication system, or portal for their particular doctor’s office. Clinicians have their own opinions about medical record systems, but what about patients?
Typically, users log into their portal with one specific purpose, then log off, and do not wish to spend too much time engaging in a health portal system. If the system is too cumbersome or difficult to use, it would reduce engagement and not achieve its intended purpose. The pr...
Source: EMR and HIPAA - August 23, 2023 Category: Information Technology Authors: Guest Author Tags: Ambulatory C-Suite Leadership Clinical Communication and Patient Experience EMR-EHR Health IT Company Healthcare IT Hospital - Health System Care Team CharmHealth Dr. Bruce Bassi HIPAA patient access Patient Portal Prescription Source Type: blogs
Fight Aging! Newsletter, August 21st 2023
This study aimed to investigate the association between frailty index and circulating CAP2 concentration in 467 community-dwelling older adults (median age: 79; range: 65-92 years). The selected robust regression model showed that circulating CAP2 concentration was not associated with chronological age, as well as sex and education. However, circulating CAP2 concentration was significantly and inversely associated with the frailty index: a 0.1-unit increase in frailty index leads to ~0.5-point mean decrease in CAP2 concentration. Furthermore, mean CAP2 concentration was significantly lower in frail participants (i.e., fr...
Source: Fight Aging! - August 21, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Definitions and Models of Disability
Alan S. Gutterman (Entrepreneurship), Definitions and Models of Disability (2023): The World Health Organization ( “WHO”) has reported that approximately 16% of the global population, over 1.3 billion people worldwide, have some form of disability, and that an additional 190 million... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - August 19, 2023 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs
On the Relationship Between Race and Disability
Jamelia Morgan (Northwestern University), On the Relationship Between Race and Disability, 58 Harv. C.R.-C.L. L. Rev. (2023): For decades, legal scholars have examined the similarities between race and disability, and in particular, the similarities between the forms of social subordination,... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - August 18, 2023 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs
