Chronic Pain Accelerates Brain Aging, Perhaps via Inflammation
A range of conditions produce chronic pain in muscle and skeletal tissue. While conditions such as osteoathritis are comparatively well understood, the etiology of chronic muscular pain disorders such as myofascial pain syndrome is poorly understood and treatment options are consequently limited. Here, researchers analyze available epidemiological data on knee osteoarthritis, and show that it suggests an inflammatory link between chronic pain and an accelerated pace of degenerative brain aging.
Individuals suffering from chronic musculoskeletal pain (CMP) may face a higher high risk of brain aging. CMP is a leadin...
Source: Fight Aging! - April 2, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Disability insurance for doctors: the key to protecting your financial future
This article is sponsored by Pattern. Pattern advisor Shelby Heiser discusses how disability insurance is more than a box that doctors need to check—it’s a tool for financial security and peace of mind. Each physician is unique. They come from different backgrounds, work in different specialties, and serve an immeasurable amount of patients, each with their
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Disability insurance for doctors: the key to protecting your financial future originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 1, 2024 Category: General Medicine Authors: Pattern & Tags: Finance Podcast Sponsored Practice Management Source Type: blogs
Fight Aging! Newsletter, April 1st 2024
This study supports the proposed model that aging-related loss of colonic crypt epithelial cell AMP gene expression can promote increased relative abundances of Gn inflammaging-associated bacteria and gene expression markers of colonic inflammaging. These data may support new targets for aging-related therapies based on intestinal genes and microbiomes.
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A Skeptical View of the Role of Nuclear DNA Damage in Aging
https://www.fightaging.org/archives/2024/03/a-skeptical-view-of-the-role-of-nuclear-dna-damage-in-aging/
It is evident and settled that stochastic nuclear DNA damag...
Source: Fight Aging! - March 31, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
How my sister ’ s rights were taken away, like thousands of others with developmental disabilities
Teresa has Down syndrome and was 49 when the capacity assessment took place in Ontario. I saw her as happy, healthy, and active. She enjoyed living nearby with my 91-year-old father, who often said, “We’re a team. We help each other.” But that’s not how the social worker saw her. Teresa didn’t understand what the
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How my sister’s rights were taken away, like thousands of others with developmental disabilities originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 29, 2024 Category: General Medicine Authors: Franke James Tags: Conditions Neurology Source Type: blogs
The Advantages, Challenges, and Costs of Healthcare at Home Services
Switching to fully remote operations during the pandemic was a rushed adventure into what was mostly uncharted territory. There were a lot of challenges and bugs to work out, but there were also plenty of advantages and unforeseen benefits. And it is thanks to those advantages and benefits that healthcare at home is continuing, even as there are still challenges to work on and in-person operations return. While our first big push into remote care was a leap into the unknown, this time we want to make sure that we are surveying the landscape to make this a safe, smart, and financially responsible decision.
So let’s ta...
Source: EMR and HIPAA - March 28, 2024 Category: Information Technology Authors: Grayson Miller Tags: Clinical Health IT Company Healthcare IT Hospital - Health System LTPAC Revenue Cycle Management Telemedicine and Remote Monitoring Alaina Victoria Ash Wellness Brenden Hayden Carenet Health Carium Chris Darland David McCormick Source Type: blogs
Predicting the Order of Arrival of the First Rejuvenation Therapies
It has been going on eight years since I last speculated on the order of arrival of the first rejuvenation therapies. Tempus fugit, and time for an updated version! Eight years is a long enough span of time for the first of those rejuvenation therapies to now exist, albeit in a prototypical form, arguably proven in principle but not concretely. The world progresses but my biases remain much the same: the first rejuvenation therapies to work well enough to merit the name will be based on the SENS vision, that aging is at root caused by a few classes of accumulated cell and tissue damage, and biotechnologies that either repa...
Source: Fight Aging! - March 25, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Medicine as a public good
Medicine is unlike most other goods and services in the extent to which it has important positive externalities – that is, benefits for people outside of the transaction, who are not the providers or consumers. (Of course it has negative externalities as well, including carbon emissions and notably, a huge quantity of plastic waste.) A straightforward positive externality is infectious disease control. Prev enting or curing infectious diseases prevents them from being transmitted to others. This is an immense benefit to society that goes far beyond the direct value to people who are vaccinated or treated.Another positive...
Source: Stayin' Alive - March 25, 2024 Category: American Health Source Type: blogs
Medical Economics
Sorry for missing a couple of days, been bizzy. Anyway, to continue with our trashing of the " discipline " of economics (which is actually more a branch of theology than a science),it should be obvious that Medicine exists in a world even
less like Economics 101 than most industries. To begin with, while our basic
needs for food, clothing and shelter are predictable and roughly similar for
everyone, our need for medical services is largely unpredictable, and it varies
radically from person to person and time to time. Some people go for decades
without really needing any at all, although there are some preventive measures
...
Source: Stayin' Alive - March 23, 2024 Category: American Health Source Type: blogs
Disability Activist: Take Great Care When Seeing Bias Toward Disabled Citizens
By RANDY SOUDERS
During the years I served as Chairman of the Board for Jean Kennedy Smith’s Arts and Disability program, Very Special Arts (VSA at the Kennedy Center), I had there opportunity to meet a wide range of remarkable and courageous disabled Americans. Among the lasting friendships is a painter and visual artist, Randy Souders, who was rendered quadriplegic at the age of 17 in a 1972 accident. His concerns of late have been heightened by Trump and MAGA Republicans. I share his communication with his permission here in the hope that tech designers and others will be alert to the fact that great care is requir...
Source: The Health Care Blog - March 20, 2024 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Disability eugenics Holocaust Mike Magee Randy Souders Trump Source Type: blogs
Medical Scientist Training Program (MSTP) Funding Opportunity and Upcoming Webinar
We’re pleased to announce our Medical Scientist Training Program (MSTP) notice of funding opportunity (NOFO) has been reissued (PAR-24-128). This NOFO continues our support of eligible, domestic organizations to develop and implement effective, evidence-informed approaches to dual-degree training and mentoring that will keep pace with the rapid evolution of the biomedical research enterprise and lead to the completion of both a clinical degree (for example, M.D., D.O., D.V.M., D.D.S., Pharm.D.) and a research doctorate degree (Ph.D.). We expect that the proposed research training programs will incorporate didactic, resea...
Source: NIGMS Feedback Loop Blog - National Institute of General Medical Sciences - March 19, 2024 Category: Biomedical Science Authors: Chrissa Chverchko Tags: Funding Opportunities Meetings/Events Training/Fellowships/Career Development Webinars Source Type: blogs
Trial By Error: David Putrino on 1) Australian Call to Scrap the Term “ Long Covid ” and 2) New Pre-Print on Sex Differences in LC
By David Tuller, DrPH Last week, just in time for Long Covid Awareness Day on Friday, the chief health officer of the Australian state of Queensland, John Gerrard, declared that the term “Long Covid” should be dropped. He based his argument on Queensland survey data suggesting that rates of prolonged disability after Covid-19 are similar … Trial By Error: David Putrino on 1) Australian Call to Scrap the Term “Long Covid” and 2) New Pre-Print on Sex Differences in LC Read More » (Source: virology blog)
Source: virology blog - March 19, 2024 Category: Virology Authors: David Tuller Tags: Uncategorized Source Type: blogs
Disability and the Ongoing Federalism Revolution
Katie R. Eyer (Rutgers University), Karen Tani (University of Pennsylvania), Disability and the Ongoing Federalism Revolution, 133 Yale L.J. (2024): The Supreme Court ’s “new federalism” revolution remains one of the most important developments in recent U.S. legal history. The Court... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - March 19, 2024 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs
Wound Care Education for Medical Doctors: Filling the Gap
Whenever I ask a group of doctors, “How many of you have had any training in care and treatment of chronic wounds?” it is the rare person who raises their hand. Despite the urgent need for medical doctors to know how to assess and treat pressure injuries and chronic wounds, there is no formal medical or surgical specialty in wound care. This has resulted in a gap in education, training, and research, with extensive variation in clinical practice. The medical education establishment has simply not caught up to the realities of care for the chronically ill patient. Filling the education gap in wound care is one of my pro...
Source: Jeffrey M. Levine MD | Geriatric Specialist | Wound Care | Pressure Ulcers - March 18, 2024 Category: Geriatrics Authors: Jeffrey M Levine Tags: An Aging World Geriatric Medicine Long-Term Care Pressure Injuries & Wound Care Risk Management aging skin bedsore bedsores decubiti decubitus ulcer end-of-life care geriatrics Healthcare Quality Improving Medical Care Jeff Lev Source Type: blogs
Goodness!
The essential, first-order or pure concept of " public goods " is whatever we benefit from that is " non-excludable " and " non-rivalrous. " That means you can use it without paying for it, and if you use it, it ' s still there for others. An example, at least for the time being, is the oxygen in the air. Back in the good old paleolithic, there was a lot more of that. Basically, the land and the water and the plants and animals were there for the taking, and there was usually plenty so rivalry was uncommon. Of course, this only worked within your own tribe -- sometimes people of different tribes tried exclusion and rivalry...
Source: Stayin' Alive - March 14, 2024 Category: American Health Source Type: blogs
Is the Aging Hippocampus Particularly Vulnerable to Blood-Brain Barrier Dysfunction?
The hippocampus in the brain is vital to cognitive functions involving learning and memory. In today's open access paper, researchers review the evidence for the hippocampus to be particularly vulnerable to damaging mechanisms, including those involved in aging. It is tentatively suggested that physiological and biochemical differences in the hippocampus point to a greater fragility of the hippocampal blood-brain barrier as a common thread underlying pathological changes observed in aging and Alzheimer's disease. The blood-brain barrier is a specialized layer of cells that wrap blood vessels passing through the central ner...
Source: Fight Aging! - March 13, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
