Reducing diagnostic delay in hypophosphatasia: a case series of 14 patients presenting to general rheumatology
ConclusionPatients with HPP can present to rheumatology with musculoskeletal pain, and if a persistently low ALP is confirmed, this may reduce the diagnostic delay of this rare disease. Similar to other rheumatologic patients, musculoskeletal pain in HPP was noted in peripheral joints and in the spine with almost a third of patients having psoriatic arthritis. Pain was also noted in the long bones, a feature consistent with metabolic bone disease. The diagnosis of HPP was also more likely in those patients with a personal or family history of dental disease or arthritis. (Source: Osteoporosis International)
Source: Osteoporosis International - April 28, 2023 Category: Orthopaedics Source Type: research

Patient reported outcomes in calcium pyrophosphate deposition disease compared to gout and osteoarthritis
CONCLUSION: Patients with CPPD may experience pain comparable to gout and OA and reported substantial unmet treatment needs.PMID:37061233 | DOI:10.3899/jrheum.2023-0031 (Source: J Rheumatol)
Source: J Rheumatol - April 15, 2023 Category: Rheumatology Authors: Mary Grace Whelan Keigo Hayashi Hallie Altwies Sara K Tedeschi Source Type: research

Patient reported outcomes in calcium pyrophosphate deposition disease compared to gout and osteoarthritis
CONCLUSION: Patients with CPPD may experience pain comparable to gout and OA and reported substantial unmet treatment needs.PMID:37061233 | DOI:10.3899/jrheum.2023-0031 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 15, 2023 Category: Rheumatology Authors: Mary Grace Whelan Keigo Hayashi Hallie Altwies Sara K Tedeschi Source Type: research

Patient reported outcomes in calcium pyrophosphate deposition disease compared to gout and osteoarthritis
CONCLUSION: Patients with CPPD may experience pain comparable to gout and OA and reported substantial unmet treatment needs.PMID:37061233 | DOI:10.3899/jrheum.2023-0031 (Source: J Rheumatol)
Source: J Rheumatol - April 15, 2023 Category: Rheumatology Authors: Mary Grace Whelan Keigo Hayashi Hallie Altwies Sara K Tedeschi Source Type: research

Patient reported outcomes in calcium pyrophosphate deposition disease compared to gout and osteoarthritis
CONCLUSION: Patients with CPPD may experience pain comparable to gout and OA and reported substantial unmet treatment needs.PMID:37061233 | DOI:10.3899/jrheum.2023-0031 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 15, 2023 Category: Rheumatology Authors: Mary Grace Whelan Keigo Hayashi Hallie Altwies Sara K Tedeschi Source Type: research

Patient reported outcomes in calcium pyrophosphate deposition disease compared to gout and osteoarthritis
CONCLUSION: Patients with CPPD may experience pain comparable to gout and OA and reported substantial unmet treatment needs.PMID:37061233 | DOI:10.3899/jrheum.2023-0031 (Source: J Rheumatol)
Source: J Rheumatol - April 15, 2023 Category: Rheumatology Authors: Mary Grace Whelan Keigo Hayashi Hallie Altwies Sara K Tedeschi Source Type: research

Patient reported outcomes in calcium pyrophosphate deposition disease compared to gout and osteoarthritis
CONCLUSION: Patients with CPPD may experience pain comparable to gout and OA and reported substantial unmet treatment needs.PMID:37061233 | DOI:10.3899/jrheum.2023-0031 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 15, 2023 Category: Rheumatology Authors: Mary Grace Whelan Keigo Hayashi Hallie Altwies Sara K Tedeschi Source Type: research

Patient reported outcomes in calcium pyrophosphate deposition disease compared to gout and osteoarthritis
CONCLUSION: Patients with CPPD may experience pain comparable to gout and OA and reported substantial unmet treatment needs.PMID:37061233 | DOI:10.3899/jrheum.2023-0031 (Source: J Rheumatol)
Source: J Rheumatol - April 15, 2023 Category: Rheumatology Authors: Mary Grace Whelan Keigo Hayashi Hallie Altwies Sara K Tedeschi Source Type: research

Patient reported outcomes in calcium pyrophosphate deposition disease compared to gout and osteoarthritis
CONCLUSION: Patients with CPPD may experience pain comparable to gout and OA and reported substantial unmet treatment needs.PMID:37061233 | DOI:10.3899/jrheum.2023-0031 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 15, 2023 Category: Rheumatology Authors: Mary Grace Whelan Keigo Hayashi Hallie Altwies Sara K Tedeschi Source Type: research

Patient reported outcomes in calcium pyrophosphate deposition disease compared to gout and osteoarthritis
CONCLUSION: Patients with CPPD may experience pain comparable to gout and OA and reported substantial unmet treatment needs.PMID:37061233 | DOI:10.3899/jrheum.2023-0031 (Source: J Rheumatol)
Source: J Rheumatol - April 15, 2023 Category: Rheumatology Authors: Mary Grace Whelan Keigo Hayashi Hallie Altwies Sara K Tedeschi Source Type: research

Patient reported outcomes in calcium pyrophosphate deposition disease compared to gout and osteoarthritis
CONCLUSION: Patients with CPPD may experience pain comparable to gout and OA and reported substantial unmet treatment needs.PMID:37061233 | DOI:10.3899/jrheum.2023-0031 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 15, 2023 Category: Rheumatology Authors: Mary Grace Whelan Keigo Hayashi Hallie Altwies Sara K Tedeschi Source Type: research

Patient reported outcomes in calcium pyrophosphate deposition disease compared to gout and osteoarthritis
CONCLUSION: Patients with CPPD may experience pain comparable to gout and OA and reported substantial unmet treatment needs.PMID:37061233 | DOI:10.3899/jrheum.2023-0031 (Source: J Rheumatol)
Source: J Rheumatol - April 15, 2023 Category: Rheumatology Authors: Mary Grace Whelan Keigo Hayashi Hallie Altwies Sara K Tedeschi Source Type: research

Patient reported outcomes in calcium pyrophosphate deposition disease compared to gout and osteoarthritis
CONCLUSION: Patients with CPPD may experience pain comparable to gout and OA and reported substantial unmet treatment needs.PMID:37061233 | DOI:10.3899/jrheum.2023-0031 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 15, 2023 Category: Rheumatology Authors: Mary Grace Whelan Keigo Hayashi Hallie Altwies Sara K Tedeschi Source Type: research