UK says Mylan recalls batches of Polish-made antibiotic
LONDON (Reuters) - U.S. drugmaker Mylan is recalling batches of the injectable antibiotic clarithromycin made in Poland due to possible impurities, Britain's healthcare regulator said on Wednesday. (Source: Reuters: Health)
Source: Reuters: Health - June 19, 2014 Category: Consumer Health News Tags: healthNews Source Type: news
UK says Mylan recalls batches of Indian-made antibiotic
LONDON (Reuters) - U.S. drugmaker Mylan is recalling batches of the injectable antibiotic clarithromycin made in India due to possible impurities, Britain's healthcare regulator said on Wednesday. (Source: Reuters: Health)
Source: Reuters: Health - June 18, 2014 Category: Consumer Health News Tags: healthNews Source Type: news
PodMed: A Medical News Roundup From Johns Hopkins (with audio)
(MedPage Today) -- This week's topics include the controversy surrounding antibacterial soaps, new high blood pressure guidelines, an interaction between calcium channel blockers and clarithromycin, and no benefits to multivitamins. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - December 20, 2013 Category: Cardiology Source Type: news
Torsades de Pointes Following Clarithromycin TreatmentTorsades de Pointes Following Clarithromycin Treatment
What factors influence this life threatening adverse event? Expert Review of Cardiovascular Therapy (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 4, 2013 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news
Antibiotic and Calcium-Channel Blocker a Fatal CombinationAntibiotic and Calcium-Channel Blocker a Fatal Combination
Significant -- and avoidable -- hospitalizations and deaths are attributed to interactions between clarithromycin and antihypertensives, coprescriptions that remain common despite warnings. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 13, 2013 Category: Consumer Health News Tags: Nephrology News Source Type: news
Use of calcium-channel blocker and antibiotic associated with small increased risk of kidney injury
Among older adults taking a calcium-channel blocker, simultaneous use of the antibiotic clarithromycin, compared with azithromycin, was associated with a small but statistically significant greater 30-day risk of hospitalization with acute kidney injury, according to a study published by JAMA. The study is being published early online to coincide with its presentation at the American Society of Nephrology's Kidney Week 2013. The commonly used antibiotics clarithromycin and erythromycin are clinically important inhibitors of the enzyme CYP3A4, while azithromycin is much less so... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 12, 2013 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news
Use of calcium-channel blocker and antibiotic associated with small increased risk of kidney injury
(The JAMA Network Journals) Among older adults taking a calcium-channel blocker, simultaneous use of the antibiotic clarithromycin, compared with azithromycin, was associated with a small but statistically significant greater 30-day risk of hospitalization with acute kidney injury, according to a study published by JAMA. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 9, 2013 Category: Global & Universal Source Type: news
Concurrent macrolide antibiotic may increase statin toxicity
Coprescription of clarithromycin or erythromycin with a statin that is metabolized by CYP3A4 increases the risk for statin toxicity in older adults, according to a population-based cohort study. (Source: theHeart.org)
Source: theHeart.org - June 18, 2013 Category: Cardiology Source Type: news
Concurrent Macrolide Antibiotic May Increase Statin ToxicityConcurrent Macrolide Antibiotic May Increase Statin Toxicity
Coprescription of clarithromycin or erythromycin with a statin that is metabolized by CYP3A4 increases the risk for statin toxicity in older adults, according to a population-based cohort study. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 17, 2013 Category: Consumer Health News Tags: Internal Medicine News Source Type: news
Antibiotic Linked to Heart Problems in COPD Patients
Study looked at clarithromycin use for lung conditions, but didn't prove cause-and-effect (Source: WebMD Health)
Source: WebMD Health - March 22, 2013 Category: Consumer Health News Source Type: news
Antibiotic Linked to Heart Problems in COPD Patients
Study looked at clarithromycin use for lung conditions, but didn't prove cause-and-effect
Source: HealthDay
Related MedlinePlus Pages: Antibiotics, COPD (Chronic Obstructive Pulmonary Disease), Heart Diseases (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - March 22, 2013 Category: Consumer Health News Source Type: news
Cardiovascular events after clarithromycin use in lower respiratory tract infections: analysis of two prospective cohort studies
Source: BMJ
Area: News
There have been concerns about the possibility of harmful effects of widespread macrolide use on cardiovascular morbidity and mortality. Whilst clarithromycin is the macrolide that is used most often in the UK, the authors report that no studies have investigated the long term effect of clarithromycin on cardiovascular events and mortality in patients after acute exacerbations of chronic obstructive pulmonary disease (COPD) or community acquired pneumonia (CAP). They conducted a secondary analysis of two large prospective cohort studies to investigate the association in these patient groups. T...
Source: NeLM - Cardiovascular Medicine - March 22, 2013 Category: Cardiology Source Type: news
Rapamune (sirolimus) tablets and oral solution - Pfizer Limited - Revised SPC
Source: eMC (electronic Medicines Compendium)
Area: Other Library Updates > SPC Changes
Section 4.5 Interaction with other medicinal products and other forms of interaction has been updated to include potential interactions with CYP3A4 inhibitors, which may decrease the metabolism of sirolimus and increase sirolimus blood levels. Such inhibitors include e.g. certain antifungals (e.g. clotrimazole, fluconazole, itraconazole, voriconazole), certain antibiotics (e.g. troleandomycin, telithromycin, clarithromycin), certain protease inhibitors (e.g. ritonavir, indinavir, boceprevir, telaprevir), nicardipine, br...
Source: NeLM - SPC Changes - March 1, 2013 Category: Drugs & Pharmacology Source Type: news
Clarithromycin and higher risk of miscarriage
Researchers in Denmark have tied the use of the antibiotic clarithromycin to an increased risk of
miscarriage-but not to an increased risk of birth defects. (Source: Modern Medicine)
Source: Modern Medicine - January 10, 2013 Category: Journals (General) Source Type: news
Antibiotic Tied to Higher Risk of Miscarriage (CME/CE)
(MedPage Today) -- Use of the antibiotic clarithromycin (Biaxin) in the first trimester of pregnancy is associated with an increased risk of miscarriage, Danish researchers reported. (Source: MedPage Today Infectious Disease)
Source: MedPage Today Infectious Disease - January 6, 2013 Category: Infectious Diseases Source Type: news
