Is there anything against Abscessus when Tygacil, Amikacin etc have failed?
Hi all, With some desperation, I am looking for some support and ideas on this forum. I have been hospitalized now 3 times for abscessus infection the last 8 years. The first 2 times I bounced back each time a bit after 11 and 6 months hospitalization, thanks to Tygacil which was just on the market. ANd then I stayed out of hospital for 3 years each time. After the birth of my daughter (a miracle!! Thx Gd!), I started crashing and was hospitalized 5 months ago. Unfortunately my abscessus is nowadays resistant against all commonly used drugs such clarithromycin,cefoxitin, moxifloxacin clofamicin,amikacin,meropenem and now...
Source: Cystic Fibrosis Adults Forum - October 1, 2015 Category: Respiratory Medicine Authors: hardclubber Tags: Adults Source Type: forums

Macrolides & Quinolones and cardiovascular risks
: The recent article published in the NEJM, has pointed out the arrhythmogenic potential not only of azithromycin but also of potential alternative antibacterial drugs, and showed an association between the use of erythromycin/clarithromycin/azithromycin and sudden cardiac death, augmented by concomitant use of inhibitors of the cytochrome P-450 3A isozymes that metabolize erythromycin. http://www.nejm.org/doi/full/10.1056/NEJMp1302726?query=TOC Also, azithromycin use was found to be associated with an increased risk of death from cardiovascular causes among patients at high baseline risk. http://www.nejm.org/doi/full/...
Source: Doc2Doc BMJ Cardiology - May 2, 2013 Category: Cardiology Authors: Dr. K. Ashutosh Source Type: forums