Comparison of the Efficacy Among Nilotinib, Dasatinib, Flumatinib and Imatinib in Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia Patients: A Real-World Multi-Center Retrospective Study
CONCLUSION: Nilotinib, dasatinib and flumatinib had comparable efficacy, and significantly higher therapy responses and higher FFS rates than imatinib in newly diagnosed CML patients. However, there were no significant differences in PFS and OS among these 4 TKIs. These real-world data may provide additional evidence for routine clinical assessments to identify more appropriate therapies.PMID:38461040 | DOI:10.1016/j.clml.2024.02.008 (Source: Clinical Lymphoma and Myeloma)
Source: Clinical Lymphoma and Myeloma - March 9, 2024 Category: Cancer & Oncology Authors: Xiaoshuai Zhang Na Xu Yunfan Yang Hai Lin Bingcheng Liu Xin Du Xiaoli Liu Rong Liang Chunyan Chen Jian Huang Huanling Zhu Ling Pan Xiaodong Wang Guohui Li Zhuogang Liu Yanqing Zhang Zhenfang Liu Jianda Hu Chunshui Liu Fei Li Wei Yang Li Meng Yanqiu Han Li Source Type: research
Inflammation as a cause of acute myocardial infarction in patients with myeloproliferative neoplasm
World J Cardiol. 2024 Feb 26;16(2):58-63. doi: 10.4330/wjc.v16.i2.58.ABSTRACTMyeloproliferative neoplasms (MPN) are a group of diseases characterized by the clonal proliferation of hematopoietic progenitor or stem cells. They are clinically classifiable into four main diseases: chronic myeloid leukemia, essential thrombocythemia, polycythemia vera, and primary myelofibrosis. These pathologies are closely related to cardio- and cerebrovascular diseases due to the increased risk of arterial thrombosis, the most common underlying cause of acute myocardial infarction. Recent evidence shows that the classical Virchow triad (hyp...
Source: World Journal of Cardiology - March 8, 2024 Category: Cardiology Authors: Amedeo Tirandi Elisa Schiavetta Elia Maioli Fabrizio Montecucco Luca Liberale Source Type: research
Inflammation as a cause of acute myocardial infarction in patients with myeloproliferative neoplasm
World J Cardiol. 2024 Feb 26;16(2):58-63. doi: 10.4330/wjc.v16.i2.58.ABSTRACTMyeloproliferative neoplasms (MPN) are a group of diseases characterized by the clonal proliferation of hematopoietic progenitor or stem cells. They are clinically classifiable into four main diseases: chronic myeloid leukemia, essential thrombocythemia, polycythemia vera, and primary myelofibrosis. These pathologies are closely related to cardio- and cerebrovascular diseases due to the increased risk of arterial thrombosis, the most common underlying cause of acute myocardial infarction. Recent evidence shows that the classical Virchow triad (hyp...
Source: World Journal of Cardiology - March 8, 2024 Category: Cardiology Authors: Amedeo Tirandi Elisa Schiavetta Elia Maioli Fabrizio Montecucco Luca Liberale Source Type: research
Inflammation as a cause of acute myocardial infarction in patients with myeloproliferative neoplasm
World J Cardiol. 2024 Feb 26;16(2):58-63. doi: 10.4330/wjc.v16.i2.58.ABSTRACTMyeloproliferative neoplasms (MPN) are a group of diseases characterized by the clonal proliferation of hematopoietic progenitor or stem cells. They are clinically classifiable into four main diseases: chronic myeloid leukemia, essential thrombocythemia, polycythemia vera, and primary myelofibrosis. These pathologies are closely related to cardio- and cerebrovascular diseases due to the increased risk of arterial thrombosis, the most common underlying cause of acute myocardial infarction. Recent evidence shows that the classical Virchow triad (hyp...
Source: World Journal of Cardiology - March 8, 2024 Category: Cardiology Authors: Amedeo Tirandi Elisa Schiavetta Elia Maioli Fabrizio Montecucco Luca Liberale Source Type: research
Inflammation as a cause of acute myocardial infarction in patients with myeloproliferative neoplasm
World J Cardiol. 2024 Feb 26;16(2):58-63. doi: 10.4330/wjc.v16.i2.58.ABSTRACTMyeloproliferative neoplasms (MPN) are a group of diseases characterized by the clonal proliferation of hematopoietic progenitor or stem cells. They are clinically classifiable into four main diseases: chronic myeloid leukemia, essential thrombocythemia, polycythemia vera, and primary myelofibrosis. These pathologies are closely related to cardio- and cerebrovascular diseases due to the increased risk of arterial thrombosis, the most common underlying cause of acute myocardial infarction. Recent evidence shows that the classical Virchow triad (hyp...
Source: World Journal of Cardiology - March 8, 2024 Category: Cardiology Authors: Amedeo Tirandi Elisa Schiavetta Elia Maioli Fabrizio Montecucco Luca Liberale Source Type: research
Inflammation as a cause of acute myocardial infarction in patients with myeloproliferative neoplasm
World J Cardiol. 2024 Feb 26;16(2):58-63. doi: 10.4330/wjc.v16.i2.58.ABSTRACTMyeloproliferative neoplasms (MPN) are a group of diseases characterized by the clonal proliferation of hematopoietic progenitor or stem cells. They are clinically classifiable into four main diseases: chronic myeloid leukemia, essential thrombocythemia, polycythemia vera, and primary myelofibrosis. These pathologies are closely related to cardio- and cerebrovascular diseases due to the increased risk of arterial thrombosis, the most common underlying cause of acute myocardial infarction. Recent evidence shows that the classical Virchow triad (hyp...
Source: World Journal of Cardiology - March 8, 2024 Category: Cardiology Authors: Amedeo Tirandi Elisa Schiavetta Elia Maioli Fabrizio Montecucco Luca Liberale Source Type: research
Inflammation as a cause of acute myocardial infarction in patients with myeloproliferative neoplasm
World J Cardiol. 2024 Feb 26;16(2):58-63. doi: 10.4330/wjc.v16.i2.58.ABSTRACTMyeloproliferative neoplasms (MPN) are a group of diseases characterized by the clonal proliferation of hematopoietic progenitor or stem cells. They are clinically classifiable into four main diseases: chronic myeloid leukemia, essential thrombocythemia, polycythemia vera, and primary myelofibrosis. These pathologies are closely related to cardio- and cerebrovascular diseases due to the increased risk of arterial thrombosis, the most common underlying cause of acute myocardial infarction. Recent evidence shows that the classical Virchow triad (hyp...
Source: World Journal of Cardiology - March 8, 2024 Category: Cardiology Authors: Amedeo Tirandi Elisa Schiavetta Elia Maioli Fabrizio Montecucco Luca Liberale Source Type: research
Inflammation as a cause of acute myocardial infarction in patients with myeloproliferative neoplasm
World J Cardiol. 2024 Feb 26;16(2):58-63. doi: 10.4330/wjc.v16.i2.58.ABSTRACTMyeloproliferative neoplasms (MPN) are a group of diseases characterized by the clonal proliferation of hematopoietic progenitor or stem cells. They are clinically classifiable into four main diseases: chronic myeloid leukemia, essential thrombocythemia, polycythemia vera, and primary myelofibrosis. These pathologies are closely related to cardio- and cerebrovascular diseases due to the increased risk of arterial thrombosis, the most common underlying cause of acute myocardial infarction. Recent evidence shows that the classical Virchow triad (hyp...
Source: World Journal of Cardiology - March 8, 2024 Category: Cardiology Authors: Amedeo Tirandi Elisa Schiavetta Elia Maioli Fabrizio Montecucco Luca Liberale Source Type: research
Inflammation as a cause of acute myocardial infarction in patients with myeloproliferative neoplasm
World J Cardiol. 2024 Feb 26;16(2):58-63. doi: 10.4330/wjc.v16.i2.58.ABSTRACTMyeloproliferative neoplasms (MPN) are a group of diseases characterized by the clonal proliferation of hematopoietic progenitor or stem cells. They are clinically classifiable into four main diseases: chronic myeloid leukemia, essential thrombocythemia, polycythemia vera, and primary myelofibrosis. These pathologies are closely related to cardio- and cerebrovascular diseases due to the increased risk of arterial thrombosis, the most common underlying cause of acute myocardial infarction. Recent evidence shows that the classical Virchow triad (hyp...
Source: World Journal of Cardiology - March 8, 2024 Category: Cardiology Authors: Amedeo Tirandi Elisa Schiavetta Elia Maioli Fabrizio Montecucco Luca Liberale Source Type: research
Inflammation as a cause of acute myocardial infarction in patients with myeloproliferative neoplasm
World J Cardiol. 2024 Feb 26;16(2):58-63. doi: 10.4330/wjc.v16.i2.58.ABSTRACTMyeloproliferative neoplasms (MPN) are a group of diseases characterized by the clonal proliferation of hematopoietic progenitor or stem cells. They are clinically classifiable into four main diseases: chronic myeloid leukemia, essential thrombocythemia, polycythemia vera, and primary myelofibrosis. These pathologies are closely related to cardio- and cerebrovascular diseases due to the increased risk of arterial thrombosis, the most common underlying cause of acute myocardial infarction. Recent evidence shows that the classical Virchow triad (hyp...
Source: World Journal of Cardiology - March 8, 2024 Category: Cardiology Authors: Amedeo Tirandi Elisa Schiavetta Elia Maioli Fabrizio Montecucco Luca Liberale Source Type: research
Inflammation as a cause of acute myocardial infarction in patients with myeloproliferative neoplasm
World J Cardiol. 2024 Feb 26;16(2):58-63. doi: 10.4330/wjc.v16.i2.58.ABSTRACTMyeloproliferative neoplasms (MPN) are a group of diseases characterized by the clonal proliferation of hematopoietic progenitor or stem cells. They are clinically classifiable into four main diseases: chronic myeloid leukemia, essential thrombocythemia, polycythemia vera, and primary myelofibrosis. These pathologies are closely related to cardio- and cerebrovascular diseases due to the increased risk of arterial thrombosis, the most common underlying cause of acute myocardial infarction. Recent evidence shows that the classical Virchow triad (hyp...
Source: World Journal of Cardiology - March 8, 2024 Category: Cardiology Authors: Amedeo Tirandi Elisa Schiavetta Elia Maioli Fabrizio Montecucco Luca Liberale Source Type: research
Inflammation as a cause of acute myocardial infarction in patients with myeloproliferative neoplasm
World J Cardiol. 2024 Feb 26;16(2):58-63. doi: 10.4330/wjc.v16.i2.58.ABSTRACTMyeloproliferative neoplasms (MPN) are a group of diseases characterized by the clonal proliferation of hematopoietic progenitor or stem cells. They are clinically classifiable into four main diseases: chronic myeloid leukemia, essential thrombocythemia, polycythemia vera, and primary myelofibrosis. These pathologies are closely related to cardio- and cerebrovascular diseases due to the increased risk of arterial thrombosis, the most common underlying cause of acute myocardial infarction. Recent evidence shows that the classical Virchow triad (hyp...
Source: World Journal of Cardiology - March 8, 2024 Category: Cardiology Authors: Amedeo Tirandi Elisa Schiavetta Elia Maioli Fabrizio Montecucco Luca Liberale Source Type: research
Inflammation as a cause of acute myocardial infarction in patients with myeloproliferative neoplasm
World J Cardiol. 2024 Feb 26;16(2):58-63. doi: 10.4330/wjc.v16.i2.58.ABSTRACTMyeloproliferative neoplasms (MPN) are a group of diseases characterized by the clonal proliferation of hematopoietic progenitor or stem cells. They are clinically classifiable into four main diseases: chronic myeloid leukemia, essential thrombocythemia, polycythemia vera, and primary myelofibrosis. These pathologies are closely related to cardio- and cerebrovascular diseases due to the increased risk of arterial thrombosis, the most common underlying cause of acute myocardial infarction. Recent evidence shows that the classical Virchow triad (hyp...
Source: World Journal of Cardiology - March 8, 2024 Category: Cardiology Authors: Amedeo Tirandi Elisa Schiavetta Elia Maioli Fabrizio Montecucco Luca Liberale Source Type: research
Inflammation as a cause of acute myocardial infarction in patients with myeloproliferative neoplasm
World J Cardiol. 2024 Feb 26;16(2):58-63. doi: 10.4330/wjc.v16.i2.58.ABSTRACTMyeloproliferative neoplasms (MPN) are a group of diseases characterized by the clonal proliferation of hematopoietic progenitor or stem cells. They are clinically classifiable into four main diseases: chronic myeloid leukemia, essential thrombocythemia, polycythemia vera, and primary myelofibrosis. These pathologies are closely related to cardio- and cerebrovascular diseases due to the increased risk of arterial thrombosis, the most common underlying cause of acute myocardial infarction. Recent evidence shows that the classical Virchow triad (hyp...
Source: World Journal of Cardiology - March 8, 2024 Category: Cardiology Authors: Amedeo Tirandi Elisa Schiavetta Elia Maioli Fabrizio Montecucco Luca Liberale Source Type: research
Inflammation as a cause of acute myocardial infarction in patients with myeloproliferative neoplasm
World J Cardiol. 2024 Feb 26;16(2):58-63. doi: 10.4330/wjc.v16.i2.58.ABSTRACTMyeloproliferative neoplasms (MPN) are a group of diseases characterized by the clonal proliferation of hematopoietic progenitor or stem cells. They are clinically classifiable into four main diseases: chronic myeloid leukemia, essential thrombocythemia, polycythemia vera, and primary myelofibrosis. These pathologies are closely related to cardio- and cerebrovascular diseases due to the increased risk of arterial thrombosis, the most common underlying cause of acute myocardial infarction. Recent evidence shows that the classical Virchow triad (hyp...
Source: World Journal of Cardiology - March 8, 2024 Category: Cardiology Authors: Amedeo Tirandi Elisa Schiavetta Elia Maioli Fabrizio Montecucco Luca Liberale Source Type: research
