Enantioselective Terminal Addition to Allenes by Dual Chiral Primary Amine/Palladium Catalysis - Journal of the American Chemical Society (ACS Publications)
We herein describe a synergistic chiral primary amine/achiral palladium catalyzed enantioselective terminal addition to allenes with α-branched β-ketocarbonyls and aldehydes. (Source: Organometallic Current)
Source: Organometallic Current - March 9, 2017 Category: Chemistry Tags: Dual Catalysis Enantioselective Pd Catalyzed Source Type: blogs
Study of Intermediates in Iridium –(Phosphoramidite,Olefin)-Catalyzed Enantioselective Allylic Substitution - Journal of the American Chemical Society (ACS Publications)
Experimental mechanistic studies of iridium-catalyzed, enantioselective allylic substitution enabled by (phosphoramidite,olefin) ligands are reported. ( η2-Allylic alcohol)iridium(I) and ( η3-allyl)iridium(III) complexes were synthesized and characterized by NMR spectroscopy as well as X-ray crystallography. (Source: Organometallic Current)
Source: Organometallic Current - March 9, 2017 Category: Chemistry Tags: Allylic Ir catalyzed Source Type: blogs
Isocyanide ‐Induced Activation of Copper Sulfate: Direct Access to Functionalized Heteroarene Sulfonic Esters
AngewchemIsocyanide ‐Induced Activation of Copper Sulfate: Direct Access to Functionalized Heteroarene Sulfonic Esters: A novel and direct approach to alkyl/aryl heteroarene sulfonic esters using copper sulfate as the environmentally benign inorganic sulfonation reagent was first realized with the aid of isocyanide. A variety... (Source: Organometallic Current)
Source: Organometallic Current - March 8, 2017 Category: Chemistry Tags: C-H Activation Cu mediated Sulfonation Source Type: blogs
Stereocontrolled Synthesis of Kalihinol C - Journal of the American Chemical Society (ACS Publications)
We report a concise chemical synthesis of kalihinol C via a possible biosynthetic intermediate, “protokalihinol”, which was targeted as a scaffold en route to antiplasmodial analogs. (Source: Organometallic Current)
Source: Organometallic Current - March 6, 2017 Category: Chemistry Tags: Total synthesis Source Type: blogs
Retraction of “Total Synthesis of Kaitocephalin, the First Naturally Occurring AMPA/KA Receptor Antagonist” - Journal of the American Chemical Society (ACS Publications)
(Source: Organometallic Current)
Source: Organometallic Current - March 6, 2017 Category: Chemistry Tags: Retraction Source Type: blogs
A Green Route to Conjugated Polyelectrolyte Interlayers for High ‐Performance Solar Cells
AngewchemA Green Route to Conjugated Polyelectrolyte Interlayers for High ‐Performance Solar Cells: Synthesis of fluorene ‐based conjugated polyelectrolytes was achieved via Suzuki polycondensation in water and completely open to air. The polyelectrolytes were conveniently purified by dialysis and analysis... (Source: Organometallic Current)
Source: Organometallic Current - March 6, 2017 Category: Chemistry Tags: Advanced materials Pd Catalyzed Solar Cell Suzuki coupling water Source Type: blogs
Cobalt-Catalyzed 1,1-Diboration of Terminal Alkynes: Scope, Mechanism, and Synthetic Applications - Journal of the American Chemical Society (ACS Publications)
A cobalt-catalyzed method for the 1,1-diboration of terminal alkynes with bis(pinacolato)diboron (B2Pin2) is described. (Source: Organometallic Current)
Source: Organometallic Current - March 2, 2017 Category: Chemistry Tags: boration Co catalyzed Source Type: blogs
Nickel Catalyzed Copolymerization of Ethylene and Alkyl Acrylates - Journal of the American Chemical Society (ACS Publications)
Ni(II) complexes bearing ano-bis(aryl)phosphinophenolate ligand were synthesized as catalysts for copolymerization of ethylene and alkyl acrylates. (Source: Organometallic Current)
Source: Organometallic Current - March 2, 2017 Category: Chemistry Tags: Copolymerization Ni Catalyzed Source Type: blogs
18F-Fluorination of Unactivated C –H Bonds in Branched Aliphatic Amino Acids: Direct Synthesis of Oncological Positron Emission Tomography Imaging Agents - Journal of the American Chemical Society (ACS Publications)
A mild and selective photocatalytic C –H18F-fluorination reaction has been developed that provides direct access to18F-fluorinated amino acids. (Source: Organometallic Current)
Source: Organometallic Current - March 2, 2017 Category: Chemistry Tags: Fluorination Source Type: blogs
Regioselective α‐Addition of Deconjugated Butenolides: Enantioselective Synthesis of Dihydrocoumarins
In this study, an unprecedented asymmetric... (Source: Organometallic Current)
Source: Organometallic Current - March 2, 2017 Category: Chemistry Tags: Enantioselective organocatalysis Source Type: blogs
Pd(II)-Catalyzed Enantioselective C(sp3) –H Borylation - Journal of the American Chemical Society (ACS Publications)
Pd(II)-catalyzed enantioselective borylation of C(sp3) –H bonds has been realized for the first time using chiral acetyl-protected aminomethyl oxazoline ligands. (Source: Organometallic Current)
Source: Organometallic Current - February 24, 2017 Category: Chemistry Tags: Borylation Enantioselective Pd Catalyzed Sp3 Functionalization Source Type: blogs
Azido and Tetrazolo 1,2,4,5 ‐Tetrazine N‐Oxides
This study presents the synthesis and characterization of the oxidation products of 3,6 ‐diazido‐1,2,4,5‐tetrazine (1) and 6‐amino‐[1,5‐b]tetrazolo‐1,2,4,5‐tetrazine (2). 3,6‐Diazido‐1,2,4,5‐tetrazine‐1,4‐dioxide... (Source: Organometallic Current)
Source: Organometallic Current - February 24, 2017 Category: Chemistry Tags: Heterocycles High Energy Materials Source Type: blogs
Polycyclic Aromatic Hydrocarbons via Iron(III)-Catalyzed Carbonyl –Olefin Metathesis - Journal of the American Chemical Society (ACS Publications)
Polycyclic aromatic hydrocarbons are important structural motifs in organic chemistry, pharmaceutical chemistry, and materials science. The development of a new synthetic strategy toward these compounds is described based on the design principle of iron(III)-catalyzed carbonyl –olefin metathesis reactions. (Source: Organometallic Current)
Source: Organometallic Current - February 22, 2017 Category: Chemistry Tags: Fe catalyzed Metathesis Polycycles Source Type: blogs
Enantioselective Alkyne Conjugate Addition Enabled by Readily Tuned Atropisomeric P,N-Ligands - Journal of the American Chemical Society (ACS Publications)
The transformation provides access to highly useful chiral β-alkynyl Meldrum’s acid building blocks as demonstrated by an efficient enantioselective synthesis of the preclinical agent OPC 51803. (Source: Organometallic Current)
Source: Organometallic Current - February 22, 2017 Category: Chemistry Tags: Alkynylation Conjugate Addition Cu catalyzed Enantioselective Source Type: blogs
Asymmetric Cu-Catalyzed Intermolecular Trifluoromethylarylation of Styrenes: Enantioselective Arylation of Benzylic Radicals - Journal of the American Chemical Society (ACS Publications)
A novel asymmetric radical trifluoromethyl-arylation of alkenes has been developed, which provides an efficient approach to access chiral CF3-containing 1,1-diarylmethane derivatives with good to excellent enantioselectivity. (Source: Organometallic Current)
Source: Organometallic Current - February 22, 2017 Category: Chemistry Tags: Arylation Cu catalyzed Enantioselective Trifluoromethylation Source Type: blogs
