Chagas' disease: A return announced
Despite deinsectization campaigns conducted in many Latin American countries, bugs called Triatoma infestans, the main vector species for Chagas' disease, are now reappearing in villages in several regions. Wild populations of Triatoma infestans are recolonizing dwellings. The latter seem very close genetically to their domestic congeners and therefore, like their domestic counterparts, are able to adapt to humans. These wild bugs thus represent a significant risk for the re-emergence of Chagas' disease, as one out of two has been shown to carry the parasite responsible for the infection. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 24, 2014 Category: Science Source Type: news
Suicide risk and alcohol and drug abuse in outpatients with HIV infection and Chagas disease - Guimarães PM, Passos SR, Calvet GA, Hökerberg YH, Lessa JL, Andrade CA.
OBJECTIVE: To evaluate psychiatric comorbidities in outpatients receiving care for HIV and Chagas disease at Instituto de Pesquisa Clínica Evandro Chagas (IPEC), Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Brazil. METHODS: Cross-sectional s... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - May 24, 2014 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news
New Drug for Chagas Disease Disappoints in 1st Human Trial
Older medication bested posaconazole, but combination of both might work well, study says
Source: HealthDay
Related MedlinePlus Pages: Chagas Disease, Medicines (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - May 16, 2014 Category: Consumer Health News Source Type: news
Chagas Disease Drug Disappoints, but Offers HopeChagas Disease Drug Disappoints, but Offers Hope
Posaconazole for Chagas disease has shown disappointing outcomes, yet hopeful signs for the future, in a clinical trial. Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 15, 2014 Category: Consumer Health News Tags: Infectious Diseases News Source Type: news
World Health Day 2014
It's World Health Day and the focus this year is on vector-borne diseases, or diseases that can be transmitted by the bite of mosquitoes, ticks, fleas, and water snails.
Unfortunately, while the CDC states that "vector-borne diseases account for 17% of the estimated global burden of all infectious diseases," it is important to remember that there are no vaccines to help prevent most of them. These diseases include dengue, schistosomiasis, leishmaniasis, Lyme disease, West Nile virus, Rocky Mountain spotted fever, Chagas disease, and malaria, which remains "one of the most severe public health problems worldwide."...Read F...
Source: About.com Pediatrics - April 7, 2014 Category: Pediatrics Source Type: news
Europe is joining forces against neglected parasitic diseases
The international consortium A-PARADDISE (Anti-Parasitic Drug Discovery in Epigenetics), coordinated by Inserm, has just obtained funds of €6 million from the European Commission to conduct large-scale testing of innovative therapies against four neglected parasitic diseases: schistosomiasis, leishmaniasis, Chagas disease and malaria. The researchers have a common objective: to develop new drugs against the parasites that cause these diseases. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 5, 2014 Category: Consumer Health News Tags: Tropical Diseases Source Type: news
Europe is joining forces against neglected parasitic diseases
(INSERM (Institut national de la santé et de la recherche médicale)) The international consortium A-PARADDISE (Anti-Parasitic Drug Discovery in Epigenetics), coordinated by Inserm, has just obtained funds of 6 million from the European Commission to conduct large-scale testing of innovative therapies against four neglected parasitic diseases: schistosomiasis, leishmaniasis, Chagas disease and malaria. The researchers have a common objective: to develop new drugs against the parasites that cause these diseases. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 3, 2014 Category: Biology Source Type: news
Analysis of archived mummy reveals murdered young female with Chagas disease
Blunt force trauma to the skull of a mummy with signs of Chagas disease may support homicide as cause of death, which is similar to previously described South American mummies, according to a study published in PLOS ONE by Stephanie Panzer from Trauma Center Murau, Germany, and colleagues, a study that has been directed by the paleopathologist Andreas Nerlich from Munich University.For over a hundred years, the unidentified mummy has been housed in the Bavarian State Archeological Collection in Germany. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 28, 2014 Category: Consumer Health News Tags: Tropical Diseases Source Type: news
Impact on mummy skull suggests murder
Blunt force trauma to the skull of a mummy with signs of Chagas disease may support homicide as cause of death, which is similar to previously described South American mummies. Radiocarbon dated to around 1450 -- 1640 AD, skeletal examination indicated that the mummy was likely 20-25 years old at the time of her death, and her skull exhibits typical Incan-type skull formations. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - February 26, 2014 Category: Science Source Type: news
Panama’s sloths harbour potential drugs
Fungi on three-toed sloth’s fur make compounds that fight bacteria, malaria and Chagas disease parasites in the lab. (Source: SciDev.Net)
Source: SciDev.Net - January 30, 2014 Category: Global & Universal Source Type: news
New drug candidates show promise for cure for Chagas disease
A team of researchers from Canada has developed a class of compounds which may help eradicate a neglected tropical disease that is currently hard to kill in its chronic form. The research was published ahead of print in Antimicrobial Agents and Chemotherapy.Chagas disease or American trypanosomiasis, caused by Trypanosoma cruzi, affects about 18 million people living mostly in Latin America. The parasite is transmitted to humans by blood-sucking reduviid bugs, also known as kissing bugs due to their predilection for feeding on the faces of their victims. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 3, 2014 Category: Consumer Health News Tags: Tropical Diseases Source Type: news
New drug candidates show promise for cure for Chagas disease
(American Society for Microbiology) A team of researchers from Canada has developed a class of compounds which may help eradicate a neglected tropical disease that is currently hard to kill in its chronic form. The research was published ahead of print in Antimicrobial Agents and Chemotherapy. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 26, 2013 Category: Global & Universal Source Type: news
According to the WHO, Neglected Tropical Diseases (NTDs) affect over 1 billion people worldwide, and are devastating to patients in the developing world. What is being done to get treatments to these patients and to speed development of new treatments?
conversationsneglected tropical diseasestropical diseasesnew medicinesInnovationOpinion46864687468846894690469246914693Neglected Tropical Diseases (NTDs) impact more than a billion people in some of the poorest, most remote parts of the world, blinding, disabling, disfiguring and sickening those infected. They have a negative impact on life expectancy, productivity and childhood education -- all of which create a cycle of poverty and stigma for affected communities.
Today, because of renewed and new commitments, millions impacted by NTDs are being treated, several NTDs are being controlled effectively, and some even elimin...
Source: PHRMA - December 10, 2013 Category: Pharmaceuticals Authors: Stephen Source Type: news
[Press Release] Deadly Gaps Persist in New Drug Development for Neglected Diseases
This study reports a slight increase of 2.4 new products/year for 2000-2011 and predicts 4.7 new products/year through 2018.
"Although strides have been made in the last decade, we still see deadly gaps in new medicines for some of the world's least visible patients," said Dr. Nathalie Strub-Wourgaft, medical director of DNDi. "We need to get more treatment candidates, NCEs or existing ones for repurposing, into and through the R&D pipeline to fundamentally change the way we manage these diseases."
"Our patients are still waiting for true medical breakthroughs," said D...
Source: MSF News - December 3, 2013 Category: Global & Universal Source Type: news
First placebo-controlled study in adults with Chagas disease highlights urgent need to scale up treatment for millions of patients at risk
According to results of the first-ever Phase 2 clinical trial in Bolivia, conducted by the Drugs for Neglected Diseases initiative (DNDi), the experimental drug candidate E1224 showed good safety and was effective at clearing the parasite that causes Chagas disease, but had little to no sustained efficacy one year after treatment as a single medication. On the other hand, standard therapy for Chagas, benznidazole, was shown to be effective in the long term but continued to be associated with side effects. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 18, 2013 Category: Consumer Health News Tags: Tropical Diseases Source Type: news
