Right Dose Right Now: bedside data-driven personalized antibiotic dosing in severe sepsis and septic shock — rationale and design of a multicenter randomized controlled superiority trial
DiscussionThis is the first randomized controlled trial to assess the effectiveness and safety of bedside data-driven automated antibiotic dosing advice. This is important as adequate antibiotic exposure may be crucial to treat severe sepsis and septic shock. In addition, the trial could prove to be a significant contribution to clinical pharmacometrics and serve as a stepping stone for the use of big data and artificial intelligence in the field.Trial registrationNetherlands Trial Register (NTR),NL6501/NTR6689. Registered on 25 August 2017.European Clinical Trials Database (EudraCT), 2017-002478-37. Registered on 6 Novemb...
Source: Trials - December 17, 2019 Category: Research Source Type: clinical trials
A Study Evaluating Efficacy and Safety of CRO-SBT in the Treatment of Gonorrhea
Condition: Gonorrhea Intervention: Drug: Ceftriaxone sodium and Sulbactam Sodium for injection Sponsor: Xiangbei Welman Pharmaceutical Co., Ltd Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 17, 2019 Category: Research Source Type: clinical trials
