Clinical Aspects of Medication Overuse Headaches.
Abstract
Medication overuse headache (MOH) is a subset of chronic daily headache, occurring from overuse of 1 or more classes of migraine abortive medication. Acetaminophen, combination analgesics (caffeine combinations), opioids, barbiturates (butalbital), non-steroidal anti-inflammatory drugs, and triptans are the main classes of drugs implicated in the genesis of MOH. Migraine seems to be the most common diagnosis leading to MOH. The development of MOH is associated with both frequency of use of medication and behavioral predispositions. MOH is not a unitary concept. The distinction between simple (type...
Source: Headache - October 10, 2013 Category: Neurology Authors: Da Silva AN, Lake AE Tags: Headache Source Type: research
Clinical Aspects of Medication Overuse Headaches
Medication overuse headache (MOH) is a subset of chronic daily headache, occurring from overuse of 1 or more classes of migraine abortive medication. Acetaminophen, combination analgesics (caffeine combinations), opioids, barbiturates (butalbital), non‐steroidal anti‐inflammatory drugs, and triptans are the main classes of drugs implicated in the genesis of MOH. Migraine seems to be the most common diagnosis leading to MOH. The development of MOH is associated with both frequency of use of medication and behavioral predispositions. MOH is not a unitary concept. The distinction between simple (type 1) vs complex (type 2...
Source: Headache: The Journal of Head and Face Pain - October 1, 2013 Category: Neurology Authors: Arnaldo Neves Da Silva, Alvin E. Lake Tags: Headache Currents—Clinical Review Source Type: research
The American Academy of Neurology's Top Five Choosing Wisely recommendations
Objective:
To discuss the American Academy of Neurology (AAN)'s Top Five Recommendations in the Choosing Wisely campaign promoting high-value neurologic medicine and physician–patient communication. The AAN published its Top Five Recommendations in February 2013 in collaboration with the American Board of Internal Medicine Foundation and Consumer Reports.
Methods:
A Choosing Wisely Working Group of 10 AAN members was formed to oversee the process and craft the evidence-based recommendations. AAN members were solicited for recommendations, the recommendations were sent out for external review, and the Working Group m...
Source: Neurology - September 9, 2013 Category: Neurology Authors: Langer-Gould, A. M., Anderson, W. E., Armstrong, M. J., Cohen, A. B., Eccher, M. A., Iverson, D. J., Potrebic, S. B., Becker, A., Larson, R., Gedan, A., Getchius, T. S. D., Gronseth, G. S. Tags: All Headache, Multiple sclerosis SPECIAL ARTICLE Source Type: research
Maternal Butalbital Use and Selected Defects in the National Birth Defects Prevention Study.
CONCLUSIONS: We observed relationships between maternal periconceptional butalbital use and certain congenital heart defects. These associations have not been reported before, and some may be spurious. Butalbital use was rare and despite the large size of the National Birth Defects Prevention Study, the number of exposed case and control infants was small. However, if confirmed in additional studies, our findings will be useful in weighing the risks and benefits of butalbital for the treatment of migraine and tension-type headaches.
PMID: 24001268 [PubMed - as supplied by publisher] (Source: Headache)
Source: Headache - September 3, 2013 Category: Neurology Authors: Browne ML, Van Zutphen AR, Botto LD, Louik C, Richardson S, Druschel CM Tags: Headache Source Type: research
Maternal Butalbital Use and Selected Defects in the National Birth Defects Prevention Study
ConclusionsWe observed relationships between maternal periconceptional butalbital use and certain congenital heart defects. These associations have not been reported before, and some may be spurious. Butalbital use was rare and despite the large size of the National Birth Defects Prevention Study, the number of exposed case and control infants was small. However, if confirmed in additional studies, our findings will be useful in weighing the risks and benefits of butalbital for the treatment of migraine and tension‐type headaches. (Source: Headache: The Journal of Head and Face Pain)
Source: Headache: The Journal of Head and Face Pain - July 1, 2013 Category: Neurology Authors: Marilyn L. Browne, Alissa R. Van Zutphen, Lorenzo D. Botto, Carol Louik, Sandra Richardson, Charlotte M. Druschel Tags: Research Submission Source Type: research
Butalbital and Driving Impairment.
Abstract
Butalbital (Fiorinal(®) ), used in the treatment of migraines and muscle pain, is the most commonly encountered barbiturate in impaired driving cases. It has central nervous system (CNS) depressant properties, including sedation, drowsiness, and feelings of intoxication, which can contribute to driving impairment. Twenty-six driving under the influence cases are reviewed including results from field sobriety tests and toxicology testing. Blood samples were screened using enzyme multiplied immunoassay technique immunoassay, and the presence of butalbital was confirmed and quantified using gas chro...
Source: Journal of Forensic Sciences - May 17, 2013 Category: Forensic Medicine Authors: Yeakel JK, Logan BK Tags: J Forensic Sci Source Type: research
