Prothrombin Complex Concentrate vs Fresh Frozen Plasma in Goal-directed Bleeding Management in Cardiac Surgery
Conditions: Cardiac Valve Disease Interventions: Biological: fresh frozen plasma; Biological: prothrombin complex concentrate Sponsors: Konkuk University Medical Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 22, 2023 Category: Research Source Type: clinical trials
Effect of TXA Oral Sol 5% in Patients Treated With DOACs or VKA and Undergoing a Single or Multiple Tooth Extraction
Conditions: Bleeding From Teeth; Bleeding Prophylaxis Interventions: Drug: Tranexamic acid Sponsors: Hyloris Developments Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 22, 2023 Category: Research Source Type: clinical trials
Prothrombin Complex Concentrate vs Fresh Frozen Plasma in Goal-directed Bleeding Management in Liver Transplantation Surgery
Conditions: Liver Diseases Interventions: Biological: fresh frozen plasma; Biological: prothrombin complex concentrate Sponsors: Konkuk University Medical Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 22, 2023 Category: Research Source Type: clinical trials
Prothrombin Complex Concentrate vs Fresh Frozen Plasma in Goal-directed Bleeding Management in Non-cardiac Surgery
Conditions: Prostate Cancer; Spine, Open; Hip Osteoarthritis; Knee Disease Interventions: Biological: fresh frozen plasma; Biological: prothrombin complex concentrate Sponsors: Konkuk University Medical Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 22, 2023 Category: Research Source Type: clinical trials
Comparing acute normovolumic hemodilution with autologous platelet-rich plasma for blood preservation during aortic surgery : study protocol for a randomized controlled clinical trial
This study aims to compare the effects of aPRP and ANH prior to aortic surgery on postoperative bleed and other outcomes.Methods and analysisThis is a prospective, single-center, double-blind controlled clinical trial including 160 patients randomized 1:1 to receive aPRP (test group) or autologous whole blood (ANH, control group). The primary objective is to compare the drainage volumes in the two groups at 24, 48, and 72 h postoperatively. Secondary outcomes include input of allogeneic blood and blood products and durations of aortic block, extracorporeal circulation, deep hypothermic arrest of circulation, tracheal extub...
Source: Trials - November 18, 2023 Category: Research Source Type: clinical trials
The SWiFT trial (Study of Whole Blood in Frontline Trauma) —the clinical and cost effectiveness of pre-hospital whole blood versus standard care in patients with life-threatening traumatic haemorrhage: study protocol for a multi-centre randomised controlled trial
DiscussionThe SWiFT trial will recruit 848 participants across at least ten air ambulances services in the UK. It will investigate the clinical and cost-effectiveness of whole blood transfusion versus component therapy in the management of patients with life-threatening bleeding in the pre-hospital setting.Trial registrationISRCTN: 23657907; EudraCT: 2021-006876-18; IRAS Number: 300414; REC: 22/SC/0072, 21 Dec 2021. (Source: Trials)
Source: Trials - November 14, 2023 Category: Research Source Type: clinical trials
Analysis of Intraoperative Bleeding Characteristics in Laparoscopic Pancreaticoduodenectomy
Conditions: Laparoscopic Pancreaticoduodenectomy Interventions: Procedure: laparoscopic pancreaticoduodenectomy Sponsors: Xinrui Zhu ，MD Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 13, 2023 Category: Research Source Type: clinical trials
Anthos Therapeutics ’ Novel Dual Acting Factor XI / XIa Inhibitor, Abelacimab 150 mg, Demonstrated a 67% Reduction in the Primary Endpoint of Major or Clinically Relevant Non-Major Bleeding Compared with Rivaroxaban in Patients with Atrial Fibrillation
CAMBRIDGE, Mass., November 12, 2023 (BUSINESS WIRE)– Anthos Therapeutics, Inc., a clinical stage company developing innovative therapies for cardiovascular diseases, founded by Blackstone Life Sciences, announced today during a Late-Breaking... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - November 12, 2023 Category: Pharmaceuticals Source Type: clinical trials
Correction: Bipolar haemostatic forceps versus standard therapy by haemoclip + / − epinephrine injection as initial endoscopic treatment in active non-variceal upper GI bleeding: study protocol for a prospective, randomized multicentre trial (BeBop-Trial)
(Source: Trials)
Source: Trials - November 10, 2023 Category: Research Source Type: clinical trials
Preemptive TIPS for Variceal Bleeding in Cirrhotic Patients With Occlusive Portal Vein Thrombosis
Conditions: Portal Hypertension; Portal Vein Thrombosis; Esophageal Varix Bleeding; Portosystemic Shunt Interventions: Procedure: preemptive TIPS; Procedure: standard second prophylaxis Sponsors: West China Hospital; The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School; Beijing YouAn Hospital; Beijing Friendship Hospital; Beijing 302 Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 8, 2023 Category: Research Source Type: clinical trials
Impact of Incomplete Endometrial Ablation
Conditions: Heavy Menstrual Bleeding Interventions: Device: hysteroscopy Sponsors: Maxima Medical Center Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 8, 2023 Category: Research Source Type: clinical trials
Preemptive TIPS for Gastric Variceal Bleeding in Patients With Cirrhosis
Conditions: Portal Hypertension; Gastric Varices Bleeding; Portosystemic Shunt Interventions: Procedure: preemptive TIPS; Procedure: standard second prophylaxis Sponsors: West China Hospital; Beijing YouAn Hospital; Renmin Hospital of Wuhan University; Second Affiliated Hospital of Nanchang University; Guangzhou First People ' s Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 8, 2023 Category: Research Source Type: clinical trials
Recombinant vWF Concentrate and ECMO
Conditions: Bleeding Disorder Interventions: Drug: Recombinant von Willebrand Factor Sponsors: University of Virginia Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 6, 2023 Category: Research Source Type: clinical trials
Initial Resuscitation With Albumin in Hemorrhagic Shock to Reduce Positive Fluid Balance
Conditions: Bleeding; Massive Hemorrhage; Massive Transfusion Protocol Interventions: Drug: Albumin solution; Drug: Balanced crystalloid solution Sponsors: Seoul National University Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 1, 2023 Category: Research Source Type: clinical trials
The Effect of ACT and Tranexamic Acid on Bleeding in Cardiac Surgery
Conditions: Surgery, Cardiac; Tranxemic Acid; Activated Clotting Time; Heparin; Cardiopulmonary Bypass Interventions: Drug: Tranexamic acid Sponsors: Taichung Veterans General Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 31, 2023 Category: Research Source Type: clinical trials
