The Role of Using Tourniquet in Decreasing Bleeding in Placenta Accreta Spectrum Cases, a Randomized Controlled Trial
Conditions: Placenta Accreta Interventions: Procedure: Uterovesical tourniquet before uterine devascularization steps; Procedure: Conventional conservative surgery Sponsors: Cairo University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 29, 2023 Category: Research Source Type: clinical trials
Recurrent or Persistent Device Related Thrombus After Left Atrial Appendage Occlusion: The RE-DRT Study
Conditions: Percutaneous Left Atrial Appendage Occlusion (LAAO); Device-related Thrombus (DRT); Thromboembolic Event; Major Cardioembolic Events; Major Bleeding - TIMI Classification Sponsors: Institut universitaire de cardiologie et de pneumologie de Qu ébec, University Laval Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 20, 2023 Category: Research Source Type: clinical trials
Establishment and Application of an Artificial Intelligence Algorithm for Automatic Identification of Intraoperative Bleeding During Laparoscopic Pancreaticoduodenectomy
Conditions: Laparoscopic Pancreaticoduodenectomy Interventions: Other: laparoscopic pancreaticoduodenectomy Sponsors: Xinrui Zhu ，MD Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 15, 2023 Category: Research Source Type: clinical trials
Obsidio ™ Conformable Embolic Registry
Conditions: Hypervascular Tumors; Bleeding; Hemorrhage Interventions: Device: Obsidio ™ Conformable Embolic Sponsors: Boston Scientific Corporation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 14, 2023 Category: Research Source Type: clinical trials
A Prospective, Post-Approval, Open-Label, Multi-Center United States (US) Registry to Evaluate the Effectiveness and Safety of Obsidio in Clinical Practice
Conditions: Hypervascular Tumors; Bleeding; Hemorrhage Interventions: Device: Obsidio ™ Conformable Embolic Sponsors: Boston Scientific Corporation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 14, 2023 Category: Research Source Type: clinical trials
Personalized, CT-guided Antithrombotic Therapy Versus Lifelong Single Antiplatelet Therapy to Reduce Thromboembolic and Bleeding Events in Non-atrial Fibrillation Patients After Transcatheter Aortic Valve Implantation
Conditions: Severe Aortic Valve Stenosis Interventions: Radiation: CT guided strategy Sponsors: St. Antonius Hospital; ZonMw: The Netherlands Organisation for Health Research and Development; Piti é-Salpêtrière Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 13, 2023 Category: Research Source Type: clinical trials
Anticoagulant-associated Intracranial Hemorrhage
Conditions: Anticoagulant-induced Bleeding; Intracranial Hemorrhages Interventions: Drug: Anticoagulant Sponsors: El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez; AstraZeneca Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 13, 2023 Category: Research Source Type: clinical trials
Metoclopramide for Gastric Visualization in Active Upper GI Bleeding
Conditions: Upper GI Bleeding Interventions: Drug: Metoclopramide Sulfone; Drug: Normal Saline 10 mL Injection Sponsors: King Chulalongkorn Memorial Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 13, 2023 Category: Research Source Type: clinical trials
Evaluation of the efficacy and safety of amustaline/glutathione pathogen-reduced RBCs in complex cardiac surgery: the Red Cell Pathogen Inactivation (ReCePI) study —protocol for a phase 3, randomized, controlled trial
DiscussionRBCs are transfused to prevent tissue hypoxia caused by surgery-induced bleeding and anemia. AKI is a sensitive indicator of renal hypoxia and a novel endpoint for assessing RBC efficacy. The ReCePI study is intended to demonstrate the non-inferiority of pathogen-reduced RBCs to conventional RBCs in the support of renal tissue oxygenation due to acute anemia and to characterize the incidence of treatment-related antibodies to RBCs. (Source: Trials)
Source: Trials - December 11, 2023 Category: Research Source Type: clinical trials
Marstacimab Phase 3 Data Presented at ASH 2023 Demonstrate Significant Bleed Reduction in Hemophilia A and B
Marstacimab reduced annualized bleeding rate by 35% and 92% compared to routine prophylaxis and on-demand treatment in patients with hemophilia A and B without inhibitors, respectively
Consistent reduction in bleeding rates observed after an... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - December 9, 2023 Category: Pharmaceuticals Source Type: clinical trials
REVISE: re-evaluating the inhibition of stress erosions in the ICU —statistical analysis plan for a randomized trial
ConclusionsThis statistical analysis plan outlines the statistical analyses of all outcomes, sensitivity analyses, and subgroup analyses. REVISE will inform clinical practice and guidelines worldwide.Trial registrationwww.ClinicalTrials.gov NCT03374800. November 21, 2017. (Source: Trials)
Source: Trials - December 6, 2023 Category: Research Source Type: clinical trials
Tranexamic acid by the intramuscular or intravenous route for the prevention of postpartum haemorrhage in women at increased risk: a randomised placebo-controlled trial (I ’M WOMAN)
DiscussionThe trial will provide evidence of the benefits and harms of TXA for PPH prevention and the effects of the IM and IV routes of administration. The IM route should be as effective as the IV route for preventing bleeding. There may be fewer side effects with IM TXA because peak blood concentrations are lower than with the IV route. IM TXA also has practical advantages as it is quicker and simpler to administer. By avoiding the need for IV line insertion and a slow IV injection, IM administration would free up overstretched midwives and doctors to focus on looking after the mother and baby and expand access to timel...
Source: Trials - December 3, 2023 Category: Research Source Type: clinical trials
Rotational Thromboelastometry [ROTEM] vs Thromboelastography [TEG] Guided Blood Component Use in Patients With Cirrhosis of Liver With Non-variceal Bleeding.
Conditions: Liver Cirrhosis Interventions: Diagnostic Test: ROTEM; Diagnostic Test: Thromboelastography Sponsors: Institute of Liver and Biliary Sciences, India Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 1, 2023 Category: Research Source Type: clinical trials
A Study to Describe the Characteristics, Health Care Interventions and Outcomes of Patients With Major Bleedings in the Presence of Factor Xa Inhibitor Treatment
Conditions: Major Bleeding Interventions: Other: None (Observational study) Sponsors: AstraZeneca; Parexel Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 28, 2023 Category: Research Source Type: clinical trials
Control of Iatrogenic Endobronchial Bleeding by Tranexamic Acid, Adrenalin and Hemagglutinase
Conditions: Iatrogenic Endobronchial Bleeding Interventions: Drug: Tranexamic Acid ；; Drug: Adrenalin; Drug: Hemagglutinase Sponsors: China-Japan Friendship Hospital; The Second Affiliated Hospital of Harbin Medical University; The First Affiliated Hospital of Nanchang University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 28, 2023 Category: Research Source Type: clinical trials
