Polycystic Ovary Syndrome: A Disorder of Reproductive Age, Its Pathogenesis, and a Discussion on the Emerging Role of Herbal Remedies
Polycystic ovary syndrome (PCOS) is a very common, complex, and heterogeneous endocrine disorder of women that involves a combination of environmental and genetic factors. PCOS affects women of growing age particularly at the early to late reproductive stage (15–35 years). Currently, PCOS affects 1 in every 10 women worldwide. It is characterized majorly by a raised level of androgens such as testosterone and a large number of ovarian cysts (more than 10) that cause anovulation, infertility, and irregular menstrual cycle. PCOS is also related to other endocrine and metabolic abnormalities, such as obesity, hirsutism, ac...
Source: Frontiers in Pharmacology - July 18, 2022 Category: Drugs & Pharmacology Source Type: research
A Preliminary Study on the Effects of Black Cohosh Preparations on Bone Metabolism of Rat Models With GnRH-a-Induced Peri-Menopausal Symptoms
CONCLUSION: The GnRH-a injection could achieve the desired effect. GnRH-a injection may lead to the loss of bone mass in rats. Black cohosh preparations, like estrogen, may have a protective effect on bone mass loss caused by GnRH-a injection.PMID:35757412 | PMC:PMC9224413 | DOI:10.3389/fendo.2022.854345 (Source: Cancer Control)
Source: Cancer Control - June 27, 2022 Category: Cancer & Oncology Authors: Zhenyue Qin Zhiyong Dong Junling Liu Ahong Zhong Mingyue Bao Huihui Wang Hongxia Yu Shoufeng Zhang Wendi Zhang Li Shen Jie Wu Jiming Chen Source Type: research
A Preliminary Study on the Effects of Black Cohosh Preparations on Bone Metabolism of Rat Models With GnRH-a-Induced Peri-Menopausal Symptoms
ConclusionThe GnRH-a injection could achieve the desired effect. GnRH-a injection may lead to the loss of bone mass in rats. Black cohosh preparations, like estrogen, may have a protective effect on bone mass loss caused by GnRH-a injection. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - June 9, 2022 Category: Endocrinology Source Type: research
Black cohosh efficacy and safety for menopausal symptoms. The Spanish Menopause Society statement
. (Source: Gynecological Endocrinology)
Source: Gynecological Endocrinology - April 11, 2022 Category: Endocrinology Authors: Camil Castelo-Branco Concepci ón Navarro Estanislao Beltr án Fernando Losa Marta Camacho Source Type: research
Benefits of Black Cohosh ( < em > Cimicifuga racemosa < /em > ) for Women Health: An Up-Close and In-Depth Review
Pharmaceuticals (Basel). 2022 Feb 23;15(3):278. doi: 10.3390/ph15030278.ABSTRACTWomen's health is an imminent concern worldwide, but it remains an ignored segment of research in most developing countries, and is yet to take the center stage in even developed nations. Some exclusive female health concerns revolve around both pathological and physiological aspects. These gender-specific maladies include breast, cervical, and ovarian cancers, and physiological concerns such as menopause and osteoporosis, which are often coexistent. Recently, women's health issues, including postmenopausal syndrome, have attracted the attentio...
Source: Cancer Control - March 26, 2022 Category: Cancer & Oncology Authors: Sradhanjali Mohapatra Ashif Iqubal Mohammad Javed Ansari Bisma Jan Sultan Zahiruddin Mohd Aamir Mirza Sayeed Ahmad Zeenat Iqbal Source Type: research
Benefits of Black Cohosh ( < em > Cimicifuga racemosa < /em > ) for Women Health: An Up-Close and In-Depth Review
Pharmaceuticals (Basel). 2022 Feb 23;15(3):278. doi: 10.3390/ph15030278.ABSTRACTWomen's health is an imminent concern worldwide, but it remains an ignored segment of research in most developing countries, and is yet to take the center stage in even developed nations. Some exclusive female health concerns revolve around both pathological and physiological aspects. These gender-specific maladies include breast, cervical, and ovarian cancers, and physiological concerns such as menopause and osteoporosis, which are often coexistent. Recently, women's health issues, including postmenopausal syndrome, have attracted the attentio...
Source: Cancer Control - March 26, 2022 Category: Cancer & Oncology Authors: Sradhanjali Mohapatra Ashif Iqubal Mohammad Javed Ansari Bisma Jan Sultan Zahiruddin Mohd Aamir Mirza Sayeed Ahmad Zeenat Iqbal Source Type: research
Actein contributes to black cohosh extract ‐induced genotoxicity in human TK6 cells
In this study, the cytotoxicity of five constituents of BCE was evaluated in human lymphoblastoid TK6 cells. Among the five constituents, actein (up to 50 μM) showed the highest cytotoxicity and was thus selected for further genotoxicity evaluations. Actein caused DNA damage proportionally to concentration as evidenced by the phosphorylation of the histone protein H2A.X (γH2A.X) and resulted in chromosomal damage as measured by the increased perc entage of micronuclei (%MN) in cells. In addition, actein activated DNA damage response (DDR) pathway through induction of p-ATM, p-Chk1, and p-Chk2, which subsequently induc...
Source: Journal of Applied Toxicology - March 15, 2022 Category: Toxicology Authors: Yuan Le,
Xilin Li,
Si Chen,
Kylie G. Ning,
Xiaoqing Guo,
Charles G. Wu,
Mugimane G. Manjanatha,
Nan Mei Tags: RESEARCH ARTICLE Source Type: research
Recognition and Prevalence of "Designated Ingredient, etc." in Health Foods
In conclusion, the recognition of "designated ingredient, etc." is insufficient. To avoid adverse events associated with "food containing designated ingredient, etc.," detailed information should be provided.PMID:35264518 | DOI:10.3358/shokueishi.63.20 (Source: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan)
Source: Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan - March 10, 2022 Category: Food Science Authors: Tsuyoshi Chiba Nanae Tanemura Chiharu Nishijima Keizo Umegaki Source Type: research
