TWiV 1025: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses the new risk assessment for the H5N1 avian flu viruses, the development of monoclonal antibody-based blocking ELISA for detecting SARS-CoV-2 exposure in animals, repeated antibiotic exposure and risk of hospitalization and death following COVID-19 infection, COVID-19 rebound study: a prospective cohort study to evaluate viral and symptom rebound differences in participants treated with Nirmatrelvir plus Ritonavir versus untreated controls, exaggerated blood pressure elevation in response to orthostatic challenge a post-acute sequelae of SARS-CoV-2 infection (PASC) after ...
Source: This Week in Virology - MP3 Edition - July 15, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 1013: Bird flu around the world
TWiV reviews remarkable changes in the epidemiology of avian H5N1 influenza virus leading to previously uninfected areas, involvement of previously unaffected wild birds, and devastating outbreaks in farmed poultry, and isolation of a monoclonal antibody against the influenza virus neuraminidase that inhibits infection with a wide range of A and B isolates. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, and Angela Mingarelli Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Register for ASV 2023 Research assistant position at FDA (pd...
Source: This Week in Virology - MP3 Edition - June 4, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Why not vaccinate chickens against avian flu, and new form of reproduction found in yellow crazy ants
Why some countries, such as China, vaccinate flocks against bird flu but others don’t, and male ants that are always chimeras   First up this week, highly pathogenic avian influenza is spreading to domestic flocks around the globe from migrating birds. Why don’t many countries vaccinate their bird herds when finding one case can mean massive culls? Staff News Writer Jon Cohen joins host Sarah Crespi to discuss the push and pull of economics, politics, and science at play in vaccinating poultry against bird flu.   Next up, a crazy method of reproduction in the yellow crazy ants (Anoplolepis gracilipes). Hugo Darra...
Source: Science Magazine Podcast - April 6, 2023 Category: Science Authors: Science Magazine Source Type: podcasts

Why not vaccinate chickens against avian flu, and new form of reproduction found in yellow crazy ants
Why some countries, such as China, vaccinate flocks against bird flu but others don’t, and male ants that are always chimeras   First up this week, highly pathogenic avian influenza is spreading to domestic flocks around the globe from migrating birds. Why don’t many countries vaccinate their bird herds when finding one case can mean massive culls? Staff News Writer Jon Cohen joins host Sarah Crespi to discuss the push and pull of economics, politics, and science at play in vaccinating poultry against bird flu.   Next up, a crazy method of reproduction in the yellow crazy ants (Anoplolepis gracilipes). Hugo Darra...
Source: Science Magazine Podcast - April 6, 2023 Category: Science Authors: Science Magazine Source Type: podcasts

How to make driverless cars safer — expose them to lots of dangerous drivers
00:46 A new test to get autonomous vehicles on the roadTruly autonomous vehicles, ones that don't require a driver to be present and are driven by AI, aren't yet safe for public use. Part of the reason for this is it has been difficult to train them to deal with rare dangerous situations. Now researchers are unveiling a new approach to present lots of these infrequent events to the AI very rapidly, speeding up the training and testing process.Research Article: Feng et al.News and Views: Hazards help autonomous cars to drive safelyVideo: The driving test for driverless cars08:23 Research HighlightsHow bird-flu is adapting t...
Source: Nature Podcast - March 22, 2023 Category: Science Authors: Springer Nature Limited Source Type: podcasts

TWiV 983: One flu vaccine for them all with Scott Hensley
Scott returns to TWiV to explain the development of an experimental mRNA vaccine that encodes hemagglutinin antigens against all known influenza A virus subtypes and influenza B virus lineages, and why he is worried about avian H5N1 influenza virus. Hosts: Vincent Racaniello, Dickson Despommier, and Brianne Barker Guest: Scott Hensley Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode •Research assistant position at FDA (pdf) •Register for ASV 2023 •MicrobeTV Discord Server •Multivalent influenza mRNA vaccine (Science) •Influenza virus mRNA v...
Source: This Week in Virology - MP3 Edition - February 12, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 982: Clinical update with Dr. Daniel Griffin
In his weekly clinical update Dr. Griffin discusses the consistency of COVID-19 trial preprints with published reports and impact for decision making, the negative effect of preexisting immunity on Influenza vaccine responses transcends the impact of vaccine formulation type and vaccination history, highly pathogenic avian influenza A(H5N1) virus infection in farmed minks in Spain, Peru confirms H5N1 avian flu in marine mammals, prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection with early activation of memory T cells followed by production of potent neutralizing antibodies, bacillu...
Source: This Week in Virology - MP3 Edition - February 11, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 777: SARS-CoV-2 fitness with Ron Fouchier
Ron Fouchier explains why increased transmission of SARS-CoV-2-variants has not been demonstrated, and their ability to displace ancestral variants is due to greater fitness, much like influenza virus antigenic variation leads to better fitness and replacement of previously circulating variants. Hosts: Vincent Racaniello, Kathy Spindler, and Brianne Barker Guest: Ron Fouchier Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Ron Fouchier on TWiV 177, 291, 557 Mutations driving H5N1 airborne transmission in ferrets (Cell) SARS-CoV and SARS-CoV-2 transmission among ...
Source: This Week in Virology - MP3 Edition - July 8, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 756: Precluding problematic polio prophylaxis
TWiV returns to the 2012 brouhaha over transmission experiments with avian H5N1 influenza virus, re-examines the claim of SARS-CoV-2 RNA integration into human DNA, and reviews the engineering and testing of a genetically stable version of the attenuated type 2 Sabin poliovirus vaccine. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Amy Rosenfeld Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode ASV vaccine town halls 3:16 First smallpox vaccine day Revised masking and distancing (CDC) Science vs Spin (Sandman) Artifactual SARS-CoV-2 in...
Source: This Week in Virology - MP3 Edition - May 16, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

The 2019 Novel Coronavirus Outbreak – Update From NIAID’s Anthony Fauci, MD
In February 2020 the nature of the 2019-nCoV outbreak is still slowly coming into focus but it appears to be acting more like bad pandemic influenza (efficient spread, overall lower mortality) than like SARS (less efficient spread, overall higher mortality). Anthony Fauci, MD, of the US National Institute of Allergy and Infectious Diseases (NIAID) discusses the latest developments with JAMA Editor in Chief Howard Bauchner. Coronavirus Resource Center (Source: JAMA Author Interviews)
Source: JAMA Author Interviews - February 7, 2020 Category: General Medicine Authors: JAMA Network Source Type: podcasts

Avian Exodus
(Source: The Discovery Files)
Source: The Discovery Files - October 3, 2019 Category: Science Authors: National Science Foundation Source Type: podcasts