Molecules, Vol. 26, Pages 2439: Antiradical Activity of Beetroot (Beta vulgaris L.) Betalains
In this study selected compounds were investigated using computational chemistry methods. Implicit water at physiological pH was chosen as the environment of interest. Betalains’ dissociation process and electronic structure were examined, as well as the reactivity in six pathways against some common radicals, such as hydroxyl, hydroperoxide, superoxide, and nitric oxide. The study showed that all carboxyl groups are dissociated in the given conditions. The dissociation process impacts the electronic structure, which has consequences for the overall activity. Highly stabilized conjugated structures favor the electron–a...
Source: Molecules - April 22, 2021 Category: Chemistry Authors: Maciej Spiegel Andrzej Gamian Zbigniew Sroka Tags: Article Source Type: research

Concentration of beetroot juice colorant (betalains) by forward osmosis and its comparison with thermal processing
Publication date: June 2021Source: LWT, Volume 145Author(s): Das Trishitman, Pradeep Singh Negi, Navin Kumar Rastogi (Source: LWT Food Science and Technology)
Source: LWT Food Science and Technology - April 21, 2021 Category: Food Science Source Type: research

Betalain Alleviates Airway Inflammation in an Ovalbumin-Induced-Asthma Mouse Model via the TGF- β1/Smad Signaling Pathway
We examined the curative potential of betalain against allergic asthma in a mouse model. Betalain treatment effectively decreased lung weight and infiltration of inflammatory cells in BAL fluid, and lowered IgE, eotaxin, and cytokine levels in asthma-induced mice. It also improved pulmonary mechanics and decreased oxidative stress and nitric oxide levels. Betalain significantly decreased gene expression of TGF-β and its downstream signaling Smad proteins. Lung histology confirmed that betalain protected the lung tissue of mice from ovalbumin-induced allergic asthma. Overall, our results show that betalain is a potent anti...
Source: Journal of Environmental Pathology, Toxicology and Oncology - April 6, 2021 Category: Environmental Health Authors: Rui Dai Yan Wang Ningling Wang Source Type: research