Cauda equina mass: An Approach
- CLINICAL PRESENTATION&FINDINGS 57 yr male with h/o low back pain with no h/o trauma presents for MRI lumbar spine which shows – Large relatively well defined , regular, intradural, subtly& heterogeneously enhancing SOL, seen from lower L3 border to middle of body of L5 with compression of cauda equina fibers, displaying mostly soft tissue signals on all sequences / normal meningeal enhancement, with no significant hemorrhage / fat / cystic / necrosis/ MR demonstrable calcification components / sugarcoating / scalloping or enlargement of the posterior neural e...
Source: Sumer's Radiology Site - January 12, 2019 Category: Radiology Authors: Sumer Sethi Source Type: blogs
Fight Aging! Newsletter, December 31st 2018
In conclusion, there are many anti-aging strategies in development, some of which have shown considerable promise for slowing down aging or delaying the onset of age-related diseases. From multiple pre-clinical studies, it appears that upregulation of autophagy through autophagy enhancers, elimination of senescent cells using senolytics, transfusion of plasma from young blood, neurogenesis and BDNF enhancement through specific drugs are promising approaches to sustain normal health during aging and also to postpone age-related diseases. However, these approaches will require critical assessment in clinical trials to determ...
Source: Fight Aging! - December 30, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Immune System Culls Harmful Senescent Cells, and Aging is Accelerated when that Function is Impaired
Cellular senescence is one of the causes of aging. Cells become senescent in response to a variety of circumstances, the most common of which is when a somatic cell reaches the Hayflick limit on replication. Senescence also arises as a result of damage, to shut down cells that might become cancerous. Senescent cells cease to replicate, issue inflammatory signals that attract immune cells to destroy them, and usually self-destruct via programmed cell death mechanisms in any case. The problem with cellular senescence arises from the tiny fraction of senescent cells that evade destruction and linger, polluting surrounding tis...
Source: Fight Aging! - December 28, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, October 8th 2018
This article, unfortunately paywalled, is interesting to note as a mark of the now increasingly energetic expansion of commercial efforts in longevity science. David Sinclair has been building a private equity company to work in many areas relevant to this present generation of commercial longevity science; while I'm not sold on his primary research interests as the basis for meaningful treatments for aging, he is diversifying considerably here, including into senolytics, the clearance of senescent cells demonstrated to produce rejuvenation in animal studies. This sort of approach to business mixes aspects of investing and...
Source: Fight Aging! - October 7, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Commentary on Recent Research into Mitochondrial DNA and Aging
Today I'll point out a commentary on recent research in which a method of degrading mitochondrial function was shown to produce aspects of accelerated aging in mice. The commentary is somewhat more approachable than the paper it comments on. The challenge here is the same as in any form of research in which something vital is broken in animal biochemistry, and wherein the result looks a lot like a faster pace of aging. These forms of artificial breakage are almost never relevant to the understanding of normal aging; they create an entirely different state of metabolism and decline.
It is true that normal aging is a ...
Source: Fight Aging! - October 1, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Understanding and improving core strength
When most people think about core strength, they think about an abdominal six-pack. While it looks good, this toned outer layer of abdominal musculature is not the same as a strong core.
What is the “core” and why is core strength so important?
The core is a group of muscles that stabilizes and controls the pelvis and spine (and therefore influences the legs and upper body). Core strength is less about power and more about the subtleties of being able to maintain the body in ideal postures — to unload the joints and promote ease of movement. For the average person, this helps them maintain the ability to get on and o...
Source: Harvard Health Blog - September 4, 2018 Category: Consumer Health News Authors: Lauren Elson, MD Tags: Exercise and Fitness Health Source Type: blogs
MKSAP: 55-year-old woman with an eating disorder
Test your medicine knowledge with the MKSAP challenge, in partnership with the American College of Physicians.
A 55-year-old woman is evaluated for a new-patient visit. Medical history is significant for an eating disorder. Although she has maintained a normal weight for the past 20 years, she notes that prior to that time her weight would fluctuate in a range correlating with BMIs of 17 to 19. She has otherwise been healthy and currently feels well. She is postmenopausal and a never-smoker. Family history is significant for postmenopausal osteoporosis in her mother. Her medications are over-the-counter calcium and vitam...
Source: Kevin, M.D. - Medical Weblog - July 23, 2018 Category: General Medicine Authors: < a href="https://www.kevinmd.com/blog/post-author/mksap" rel="tag" > mksap < /a > Tags: Conditions Endocrinology Source Type: blogs
Tropical Travel Trouble 008 Total TB Extravaganza
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog
aka Tropical Travel Trouble 008
Peer Reviewer Dr McBride ID physician, Wisconsin
TB affects 1/3rd of the population and one patient dies every 20 seconds from TB. Without treatment 50% of pulmonary TB patients will be dead in 5 years. In low to middle income countries both TB and HIV can be ubiquitous, poor compliance can lead to drug resistance and malnourished infants are highly susceptible. TB can be very complex and this post will hopefully give you the backbone to TB m...
Source: Life in the Fast Lane - June 16, 2018 Category: Emergency Medicine Authors: Neil Long Tags: Clinical Cases Tropical Medicine Genexpert meningitis TB TB meningitis Tuberculosis Source Type: blogs
Accuro Helps to Make Epidurals and Spinals Easier: Interview with Will Mauldin, CEO of Rivanna Medical
Performing epidural and spinal anesthesia requires a good deal of training and being able to sense when the needle reaches the desired location. This is certainly not foolproof and some patients are harder to work with than others. One issue is that a sonographer is usually required to operate the ultrasound while the anesthesiologist delivers the needle. Accuro, a new ultrasound device recently cleared by the FDA, offers capabilities that can alleviate a sonographer from having to help with epidurals and spinals. We wanted to learn more and took a chance to ask some question of Will Mauldin, CEO of Rivanna Medical, the Ch...
Source: Medgadget - April 30, 2018 Category: Medical Devices Authors: Editors Tags: Anesthesiology Neurology Pain Management Source Type: blogs
Robotic Brace Characterizes Spine Deformities, Dynamically Adjusts Therapy
This study is foundational and we believe will lead to exciting advances both in characterizing and treating spine deformities.”
The brace includes three rings that are situated on the upper-thoracic, mid-thoracic and pelvic spinal regions. A robotic actuator controlled by 12 motors is included in the system. The robot controls the movement of the upper rings and can apply controlled forces on these rings to help correct a spinal curvature, while allowing the patient to move freely in other directions.
“We built upon the principles used in conventional spine braces, i.e., to provide three-point loading at the curve ape...
Source: Medgadget - April 10, 2018 Category: Medical Devices Authors: Conn Hastings Tags: Orthopedic Surgery Pediatrics Rehab Source Type: blogs
Dextrocardia and dextroposition
Dextrocardia with situs inversus
Dextrocardia is evident as the apex is pointing to the right and the right atrial contour is on the left. The gastric air bubble is on the right (below the diaphragm) and liver shadow on the left, indicating situs inversus. The ascending aortic shadow on the left is a little prominent. There is mild scoliosis with convexity to the left which could be partly positional. Crowding of upper ribs on the right side could be due to the scoliosis.
Left sided pleural effusion with dextroposition
There is massive pleural effusion on the left side pushing the heart along with the mediastinum to the r...
Source: Cardiophile MD - October 29, 2017 Category: Cardiology Authors: Johnson Francis Tags: Cardiology X-ray Source Type: blogs
MedTech Innovator Applications Are Open!
The premiere medical technology start-up competition has just announced they are accepting applications for their next batch of world changing companies. Medgadget had the chance to be present at the last MedTech innovator finals held at AdvaMed in Minneapolis this past October, which was clearly the highlight of the entire conference. Attendees were on the edge of their seats as the finalists laid out their personal stories and health-oriented technologies. The crowd, by popular vote, laid down judgement on our hopeful finalists awarding the grand prize to Green Sun Medical.
We had a chance to sit down with some of MedTec...
Source: Medgadget - January 20, 2017 Category: Medical Equipment Authors: Justin Barad Tags: News Source Type: blogs
DM / DNB Cardiology Entrance New Test Series 5
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Source: Cardiophile MD - August 6, 2016 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology Cardiology MCQ DM / DNB Cardiology Entrance Featured Source Type: blogs
Medtech Innovator 2016 Semi-Finalists Announced
MedTech Innovator, the medtech industry’s annual start-up competition and virtual accelerator, has just announced their 20 semi-finalists. 430 companies from around the globe applied for these coveted spots, and were reviewed by 90 reviewers from 50 different companies. These ground-breaking semi-finalists will undergo a four month virtual accelerator before attending AdvaMed 2016. There, four finalists will be selected to present and compete for $250,000 in cash prizes, with the winner being selected by audience vote. In addition, throughout the year there will be additional awards given in three areas: Value, Ex...
Source: Medgadget - July 6, 2016 Category: Medical Equipment Authors: Justin Barad Tags: Exclusive News Source Type: blogs
How Does Vaccinated Children’s Health Compare to Unvaccinated Children?
Conclusion
While government groups maintain that no studies have been done to compare the health of vaccinated to unvaccinated, the reality is that several comparative studies have been completed by independent researchers in the US and in other countries.
The Centers for Disease Control and Prevention refuses to conduct such studies, claiming they would be unethical to perform. In reality, these studies could easily be performed, since many educated parents choose to not vaccinate their children.
The evidence is overwhelming. Studies completed in New Zealand, Germany, Africa, Great Britain and the United States have come ...
Source: vactruth.com - June 3, 2016 Category: Allergy & Immunology Authors: Michelle Goldstein Tags: Logical Michelle Goldstein Top Picks Top Stories truth about vaccines vaccinated vs. unvaccinated Source Type: blogs
