In a First, Doctors Treat a Fatal Genetic Disease Before Birth
A toddler is thriving after doctors in the U.S. and Canada used a novel technique to treat her before she was born for a rare genetic disease that caused the deaths of two of her sisters.
Ayla Bashir, a 16-month-old from Ottawa, Ontario, is the first child treated as fetus for Pompe disease, an inherited and often fatal disorder in which the body fails to make some or all of a crucial protein.
Today, she’s an active, happy girl who has met her developmental milestones, according to her father, Zahid Bashir and mother, Sobia Qureshi.
“She’s just a regular little 1½-year-old who keeps us on our toes,...
Source: TIME: Health - November 10, 2022 Category: Consumer Health News Authors: JONEL ALECCIA/AP Tags: Uncategorized Disease healthscienceclimate wire Source Type: news
New TREMFYA ® (guselkumab) Post-Hoc Analysis Reveals Active Psoriatic Arthritis Patients With Early Efficacy Had Meaningful Long-Term Improvement in Health-Related Quality of Life
SPRING HOUSE, PENNSYLVANIA, November 10, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced a new post-hoc analysis of the Phase 3 DISCOVER-2 study that show early (week 8) clinical improvementsa of most measures (joint and skin disease, enthesitis and dactylitis) in adult patients with active psoriatic arthritis (PsA) treated with TREMFYA® (guselkumab) were associated with meaningful improvements in health-related quality of life (HRQoL) (measured by EQ-5D)b from year one (week 52) through year two (week 100).1 TREMFYA is the first fully human selective interleukin (IL)-23 inhibitor th...
Source: Johnson and Johnson - November 10, 2022 Category: Pharmaceuticals Tags: Latest News Source Type: news
Definitive Answer on Steroids for Infant Heart Surgery Falls Short
(MedPage Today) -- Babies given perioperative methylprednisolone to reduce inflammation from cardiopulmonary bypass didn't do better overall in a randomized trial nestled within a registry, although secondary outcomes and a Bayesian win ratio analysis... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - November 6, 2022 Category: Cardiology Source Type: news
RSV Cases Are Rising in Kids and Babies. What Parents Should Know
On top of continued concerns about COVID-19 and the anticipated wave of flu cases this fall and winter, health experts are also confronting another infectious disease: Respiratory syncytial virus (RSV).
RSV typically strikes during the colder months, when people gather indoors and are more likely to spread disease through close contact and respiratory droplets. It’s particularly common among infants and young children, as well as the elderly, who are more vulnerable to infections because of their less developed or weakened immune systems.
After years of having no vaccines against the virus, scientists are moving quic...
Source: TIME: Health - November 1, 2022 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 healthscienceclimate Public Health Source Type: news
The Troubling Trends Pointing to a Severe Flu and RSV Season
Flu and respiratory syncytial virus (RSV) season has just begun in the northern hemisphere, and the consensus among experts is that the 2022-2023 season is shaping up to be more severe than in the past few (relatively mild) years. It might even be worse than seasons before COVID-19.
Health data company IQVIA has been analyzing data from insurance claims filed by doctors’ offices, hospitals, and urgent care centers in the country for three decades, and focused on case trends over the previous year. The team found that diagnoses of flu are already tracking at record highs. Even before flu season began, back in spring 2...
Source: TIME: Health - October 25, 2022 Category: Consumer Health News Authors: Alice Park and Charts by Emily Barone Tags: Uncategorized COVID-19 healthscienceclimate Source Type: news
For Kids with Long COVID, Good Treatment Is Hard to Find
Ayden Varno was outside doing chores one day in April 2021 when he felt an excruciating pain, like “a hot knife was being stabbed into my back multiple times,” he says.
Ayden, who is now 13, spent most of the next eight months in pain so extreme he couldn’t walk unassisted, sleep through the night, or follow a full school curriculum. He also suffered frequent non-epileptic seizures related to his pain. Doctors near his home in Ohio had no idea why Ayden was in so much pain or what to do about it; some suggested he was having a psychotic episode or being abused at home, says his mother, Lynda Varno. The fa...
Source: TIME: Health - October 24, 2022 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized COVID-19 feature healthscienceclimate Source Type: news
New TREMFYA ® (guselkumab) Data Show an Overall Clinical Response Rate of Approximately 80 Percent in a Phase 2b Induction Study of Adults with Moderately to Severely Active Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, October 24, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new data from the Phase 2b QUASAR Induction Study 1 in adults with moderately to severely active ulcerative colitis (UC) with inadequate responses to previous treatments. The data presented at the 2022 American College of Gastroenterology (ACG) Annual Scientific Meeting show an overall clinical response rate of approximately 80 percent in patients who were randomized to TREMFYA® (guselkumab).Clinical responsea at weeks 12 or 24 of the study was ultimately achieved by 80.2 percent of patients who w...
Source: Johnson and Johnson - October 24, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news
Which Side Are the Organs On?
Discussion
Although externally vertebrates present with bilateral symmetry, this is not necessarily true internally for humans. Humans have a normal left-right asymmetry of their internal organs. For example, the right lung has 3 lobes and is slightly larger than the left lung with 2 lobes. The normal asymmetry is called situs solitus (SS). Complete reversal of the normal abdominal and thoracic organ positions is called situs inversus totalis (SIT). Variations on the laterality between situs solitus and SIT has been referred to by different names including situs ambiguous or heterotaxy. For this case, the term situs ambigu...
Source: PediatricEducation.org - October 17, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Spanish Baby Gets Pioneering Intestine Transplant Spanish Baby Gets Pioneering Intestine Transplant
A 1-year-old Spanish girl has become the world ' s first recipient of a successful intestine transplant from a donor who died of heart failure, Madrid ' s La Paz hospital said on Tuesday.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - October 12, 2022 Category: Surgery Tags: Pediatrics News Source Type: news
Spanish baby in 'perfect condition' after pioneering intestine transplant, hospital says
A Spanish baby has become the world's first recipient of a successful intestine transplant from a donor who died of heart failure, hospital officials say. (Source: CBC | Health)
Source: CBC | Health - October 11, 2022 Category: Consumer Health News Tags: News/Health Source Type: news
AHA News: 11-Year-Old Heart Defect Survivor Is Living Life Wholeheartedly
TUESDAY, Oct. 11, 2022 (American Heart Association News) -- It started with the ultrasounds. Every time Anita Naglieri had one, her OB-GYN said she could only see half her baby ' s heart. " Don ' t worry, " the doctor told her. " It ' s probably just the... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 11, 2022 Category: General Medicine Source Type: news
STELARA ® (ustekinumab) Demonstrated Sustained Symptomatic and Corticosteroid-Free Remission Through Four Years in Adults with Moderately to Severely Active Ulcerative Colitis
SPRING HOUSE, PENNSYLVANIA, October 10, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced final data from the long-term extension (LTE) of the Phase 3 UNIFI study demonstrating efficacy and safety of STELARA® (ustekinumab) through four years of treatment in adult patients with moderately to severely active ulcerative colitis (UC).1 Among all patients who had achieved clinical responsea with STELARA during induction, 64.9 percent were in symptomatic remissionb after 44 weeks of maintenance. At week 200 (four years), this proportion of patients was 55.2 percent; the majority (96.4 percen...
Source: Johnson and Johnson - October 10, 2022 Category: Pharmaceuticals Source Type: news
Results of Novel Clinical Study of Guselkumab and Golimumab Combination Therapy Show Adults with Moderately to Severely Active Ulcerative Colitis Maintained Higher Rates of Clinical, Histologic, and Endoscopic Remission at Week 38
SPRING HOUSE, PENNSYLVANIA, October 10, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from an ongoing analysis of a Phase 2a clinical trial showing adults with moderately to severely active ulcerative colitis (UC) who received 12 weeks of combination induction therapy with guselkumab and golimumab, followed by a transition to guselkumab alone for maintenance, achieved a clinical remission ratea (based on the modified Mayo score [mMayo])b at week 38 of 47.9 percent, a higher rate than induction and maintenance treatment with either guselkumab alone (31.0 percent) or golimumab al...
Source: Johnson and Johnson - October 10, 2022 Category: Pharmaceuticals Source Type: news
Syphilis Is Rising in the U.S. Here ’ s What to Know About the Sexually Transmitted Infection
Sexually transmitted infections are rising in the U.S.—particularly syphilis, which increased by 26% from 2020 to 2021, according to preliminary data from the U.S. Centers for Disease Control and Prevention (CDC) published in September. Especially troubling is a 24% rise during that time period of congenital syphilis, which infects fetuses in the womb and can cause birth defects in or even kill infants.
Fortunately, syphilis can be easily treated and cured. However, people who are infected don’t necessarily know it—and without detection and treatment, the disease can have devastating consequences.
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Source: TIME: Health - September 27, 2022 Category: Consumer Health News Authors: Tara Law Tags: Uncategorized COVID-19 Disease healthscienceclimate Source Type: news
World-first partial heart transplant with 'living tissue' saves baby boy born with fused arteries
Owen Monroe, from North Carolina, was born with his two main arteries fused together. Doctors used living tissue to seprate them and replace heart valves, which will grow with the infant. (Source: the Mail online | Health)
Source: the Mail online | Health - September 12, 2022 Category: Consumer Health News Source Type: news
