Featured review: Low-dose misoprostol given by mouth for induction of labour
First author of this new Cochrane Review,' Low ‐dose oral misoprostol for induction of labour ' , Robert Kerr explains, “Our review found that Misoprostol given orally outperforms the ‘gold-standard’ drug which is much more expensive, and used in preference in many countries. This review has the potential to impact millions of women and babies who have inductions of labour through its comparison of oral misopro stol with other commonly used induction techniques. " Labour inductions are common around the world. Induction rates vary worldwide, but for example in the UK, 1 in 3 women will have labour induced. Inducti...
Source: Cochrane News and Events - June 28, 2021 Category: Information Technology Authors: Lydia Parsonson Source Type: news

Janssen Submits New Drug Application to U.S. FDA for XARELTO ® (rivaroxaban) to Help Prevent and Treat Blood Clots in Pediatric Patients
RARITAN, NJ, June 23, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today it has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for the use of XARELTO® (rivaroxaban) in pediatric patients. The NDA seeks two pediatric indications: treatment of venous thromboembolism (VTE, or blood clots) and reduction in the risk of recurrent VTE in patients aged birth to less than 18 years of age after at least five days of initial parenteral anticoagulant treatment; and thromboprophylaxis (prevention of blood clots) in patients aged 2 years and older with congenita...
Source: Johnson and Johnson - June 23, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Too Many Older Americans Are Taking Daily Aspirin
TUESDAY, June 22, 2021 -- Many older adults are still taking a daily baby aspirin to ward off first-time heart problems— despite guidelines that now discourage it, a new study finds. Researchers found that one-half to 62% of U.S. adults aged... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - June 22, 2021 Category: General Medicine Source Type: news

AHA News: Preterm Babies May Have Higher Stroke Risk as Young Adults
Title: AHA News: Preterm Babies May Have Higher Stroke Risk as Young AdultsCategory: Health NewsCreated: 6/17/2021 12:00:00 AMLast Editorial Review: 6/18/2021 12:00:00 AM (Source: MedicineNet Heart General)
Source: MedicineNet Heart General - June 18, 2021 Category: Cardiology Source Type: news

AHA News: Preterm Babies May Have Higher Stroke Risk as Young Adults
THURSDAY, June 17, 2021 (American Heart Association News) -- Babies born prematurely may have significantly higher risk of stroke as young adults– and the earlier the birth, the greater the risk, suggests an extensive new study. Although... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - June 17, 2021 Category: General Medicine Source Type: news

Almost 25% of COVID-19 Patients Develop Long-Lasting Symptoms, According to a New Report
A year and a half into the pandemic, the condition known as Long COVID continues to stump doctors. A significant number of patients develop long-term symptoms after catching COVID-19, but it hasn’t been clear why that happens, who is likely to get sick or even how many people continue to suffer. A large new study may help form some answers to those questions. In line with prior estimates, it finds that almost a quarter of people infected with the virus develop at least one lingering health problem, and that most Long COVID symptoms are more commonly reported by women than men. [time-brightcove not-tgx=”trueR...
Source: TIME: Health - June 15, 2021 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized COVID-19 Source Type: news

‘A Year Full of Emotions.’ What Kids Learned From the COVID-19 Pandemic
Too many young generations have been shaped by the global crises they faced—Depression-era poverty, Cold War nuclear fears. Add to them the COVID generation. The virus itself may typically go easier on kids than it does adults, but the mind of a child is another thing. It’s dependent on certainty, safety, the comfort of routine. Take all of that away—shutter schools, keep grandparents at a distance, cancel summer camps—and kids suffer. But as the following lightly-edited stories from young people show, they also grow and learn, gain maturity and wisdom. The virus has been tough; plenty of kids, it t...
Source: TIME: Health - June 12, 2021 Category: Consumer Health News Authors: Jeffrey Kluger and Allison Singer Tags: Uncategorized COVID-19 Source Type: news

New Phase 3b Psoriatic Arthritis (PsA) Data Show First-in-Class TREMFYA ® (guselkumab) Achieved Robust Joint Symptom Improvement and Complete Skin Clearance in Patients with Inadequate Response to Tumor Necrosis Factor Inhibition (TNFi-IR)
SPRING HOUSE, PENNSYLVANIA, June 2, 2021 – Today the Janssen Pharmaceutical Companies of Johnson & Johnson announced new efficacy and safety data for first-in-class TREMFYA® (guselkumab), including data from the first study evaluating a selective IL-23 inhibitor in adult patients with active PsA, all of whom had demonstrated inadequate response or intolerance to TNFi.1 In the COSMOS Phase 3b study, significantly higher proportions of patients treated with TREMFYA showed joint symptom improvement and complete skin clearance versus placebo at week 24 in this true TNFi-IRa patient population, which is often more diffic...
Source: Johnson and Johnson - June 2, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

UCLA Health clinic helps mom heal after near-death birth experience
Marisa Peters, a 38-year-old mom of three, expected the delivery of her third child to be ordinary and uneventful, just like the births of her two other children. But right after her water broke at Ronald Reagan UCLA Medical Center on Feb. 6, 2019, she became quickly aware that this delivery would be very different.The first sign was a high fever that escalated rapidly. Then she developed an infection and began experiencing full-body convulsions, which were followed by a painful singular contraction that lasted for one hour. During this time, the baby ’s heart rate dipped, but she was lucky to catch a small window of tim...
Source: UCLA Newsroom: Health Sciences - May 26, 2021 Category: Universities & Medical Training Source Type: news

Janssen Presents Results of First Head-to-Head Study of Biologic Therapies in Patients with Moderate to Severe Crohn ’s Disease
SPRING HOUSE, PENNSYLVANIA, May 23, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced efficacy and safety data for STELARA® (ustekinumab) in Crohn’s disease (CD) and ulcerative colitis (UC),1-4including data from the SEAVUE study, the first head-to-head study of biologic therapies in patients with CD, presented in a Clinical Science Late-Breaking Abstract Plenary session.1 SEAVUE data showed treatment with STELARA demonstrated high rates of clinical remission, corticosteroid-free remission, clinical response and endoscopic response through one year in biologic-naïve patients with mo...
Source: Johnson and Johnson - May 24, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

AHA News: A Baby's Gut Bacteria May Predict Future Obesity
THURSDAY, May 20, 2021 (American Heart Association News) -- New research into the growing problem of early childhood obesity suggests the bacteria in a baby ' s gut may indicate weight problems in the years to come. Researchers examined gut microbiota... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - May 20, 2021 Category: General Medicine Source Type: news

Late-Breaking Data at ACC.21 Show XARELTO ® (rivaroxaban) Plus Aspirin Significantly Reduced Total Ischemic Events in Peripheral Artery Disease (PAD) Patients After Lower-Extremity Revascularization
RARITAN, N.J., May 16, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today presented new data from the Phase 3 VOYAGER PAD study which showed XARELTO® (rivaroxaban) (2.5 mg twice daily) in combination with aspirin (100 mg once daily) consistently reduced severe vascular events in patients with peripheral artery disease (PAD) after lower-extremity revascularization (LER) compared to aspirin alone regardless of whether it was the first, second, third, or subsequent event. The primary results of VOYAGER PAD showed that XARELTO® plus aspirin reduced first events by 15 percent among patients with PAD ...
Source: Johnson and Johnson - May 16, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

AHA News: Preterm Deliveries May Pose Long-Term Stroke Risk for Mothers
MONDAY, May 10, 2021 (American Heart Association News) -- It ' s not surprising that babies born prematurely may face more health issues than those who were carried to term. But new research suggests the same may apply to their mothers. A study... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - May 10, 2021 Category: General Medicine Source Type: news

Genetically Modified Mosquitoes Have Come to the U.S. Will They Work?
“Our Mosquito Project Takes Flight,” reads a baby-blue billboard off US-1 in the Florida Keys, alongside an image of an insect tracing a path in the shape of a heart. Sponsored by the local mosquito control board and U.K.-based biotech firm Oxitec, the ad promotes a contentious plan to release millions of genetically modified Aedes aegypti mosquitoes here to test a new method of bioengineered pest control. It’s the first-ever such experiment in the United States, and one that has turned this chain of sun-soaked island communities into a battleground over scientific truth, government authority, and humanit...
Source: TIME: Health - May 9, 2021 Category: Consumer Health News Authors: Alejandro de la Garza / Florida Keys, Fl. Tags: Uncategorized Source Type: news

Researchers describe rare case of heart rhythm problem in newborn with Turner syndrome
(Boston University School of Medicine) Doctors treating babies born with Turner syndrome need to look for heart rhythm abnormalities, in addition to the usual heart problems of high blood pressure or left-sided structural heart defects, according to Meena Bolourchi, MD, assistant professor of pediatrics at Boston University School of Medicine. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 30, 2021 Category: International Medicine & Public Health Source Type: news