2022 Demystifying Medicine Lecture Series: Epigenetic Contribution to Autoimmune Diseases / Anticytokine Autoantibodies: Important Underappreciated Cofactors in Rare and Common Conditions
Jointly sponsored by FAES and NIH, the Demystifying Medicine course aims to bridge exciting developments in medicine with advances in the basic biological and engineering sciences. When possible, a live patient introduces the course topic by discussing their disease, followed by a physician scientist who describes clinical aspects of the disease including therapy and challenges, followed by bench scientist who describes what we know and don't know regarding mechanism. The course is designed to excite as well as inform medical and Ph.D. students, fellows, basic and physician scientists, and program planners.For more informa...
Source: Videocast - All Events - December 10, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video

Imaging Inflammation Resolution and Wound Repair
Speaker Anna Huttenlocher's research focuses on understanding the basic molecular mechanisms that regulate cell movement — in the context of wound healing, inflammation and cancer. Cell migration plays a central role in many different disease processes including cancer, heart disease and autoimmune disease. Insight into the mechanisms that regulate cell migration will contribute to our understanding of basic cellular processes, but will also aid in the identification of new treatment strategies for a wide variety of medical conditions. Despite extensive interest in the receptors and mechanisms involved during cell migrat...
Source: Videocast - All Events - November 26, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video

Biomaterials for combination immunotherapy
Biomedical Engineering Scientific Interest Group(BMESIG) seminar series: Lecture by Dr.Natalie Artzi, Assistant Professor of Medicine, Brigham and Women ’ s Hospital, Harvard Medical School; Principal Research Scientist, MIT; Associate Member, Broad Institute of Harvard and MIT. The power of leveraging the patient ’ s own immune system to fight diseases is increasingly being recognized. This talk will explore medical technologies being developed that harness lessons from biomaterial development for drug delivery systems to those that will reprogram the immune system to generate robust and long-lasting curative outcomes...
Source: Videocast - All Events - October 27, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video

NIH Glycobiology Special Topics Seminar: Role of glycosylation in the immune system and autoimmune diseases
This special topics lecture series will provide an overview of the fundamental facts, concepts, and methods concerning glycosylation with an emphasis on aspects relevant to human health and disease.Air date: 8/18/2021 9:00:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - August 10, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video

Accelerating Progress in Celiac Disease Research Workshop (Day 1)
Celiac disease is an autoimmune disease that occurs in genetically susceptible individuals who develop an immune response to ingested gluten. This disease affects greater than 1% of the US population, and incidence appears to have been increasing over the last several decades. The only known treatment is life-long strict avoidance of all forms of wheat, rye, and barley. Although a gluten-free diet is an effective treatment in many individuals, recent research has revealed that up to 50% of individuals following a gluten-free diet are inadvertently exposed to gluten, and a substantial minority develop persistent or recurren...
Source: Videocast - All Events - March 11, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video

Accelerating Progress in Celiac Disease Research Workshop (day 2)
Celiac disease is an autoimmune disease that occurs in genetically susceptible individuals who develop an immune response to ingested gluten. This disease affects greater than 1% of the US population, and incidence appears to have been increasing over the last several decades. The only known treatment is life-long strict avoidance of all forms of wheat, rye, and barley. Although a gluten-free diet is an effective treatment in many individuals, recent research has revealed that up to 50% of individuals following a gluten-free diet are inadvertently exposed to gluten, and a substantial minority develop persistent or recurren...
Source: Videocast - All Events - March 10, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video

Accelerating Progress in Celiac Disease Research Workshop
Celiac disease is an autoimmune disease that occurs in genetically susceptible individuals who develop an immune response to ingested gluten. This disease affects greater than 1% of the US population, and incidence appears to have been increasing over the last several decades. The only known treatment is life-long strict avoidance of all forms of wheat, rye, and barley. Although a gluten-free diet is an effective treatment in many individuals, recent research has revealed that up to 50% of individuals following a gluten-free diet are inadvertently exposed to gluten, and a substantial minority develop persistent or recurren...
Source: Videocast - All Events - March 10, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video

Casting the Net Wide: the Role of Neutrophils in Chronic Diseases
This is a rescheduled Mider Lecture. Speaker Mariana Kaplan, NIH NIAMS, focuses on identifying mechanisms of immune dysregulation, organ damage and premature vascular disease in systemic autoimmunity. More specifically, she investigates how innate immunity (in particular, type I interferons and myeloid cells) promote end-organ damage in systemic lupus erythematosus, rheumatoid arthritis and other systemic autoimmune diseases.For more information go tohttps://oir.nih.gov/walsAir date: 6/9/2021 3:00:00 PM (Source: Videocast - All Events)
Source: Videocast - All Events - February 11, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video

Protective and Pathogenic B Cell Responses: COVID-19 and Autoimmunity
Dr. Sanz's research interest is in understanding how the immune system goes awry in autoimmune diseases and ends up attacking our own tissues rather than concentrating on fighting infections. In particular, he is very interested in understanding the roles played in autoimmune diseases by B cells and their effector progeny, the plasma cells responsible for producing the autoantibodies that in many cases cause the disease. His research concentrates on systemic lupus erythematosus, but he is also investigating other autoimmune diseases such as Sjogren's syndrome, rheumatoid arthritis and type 1 diabetes. His work also has app...
Source: Videocast - All Events - January 19, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video

Demystifying Medicine - Encephalitis and the Immune System
Demystifying Medicine Lecture Series Encephalitis, the inflammation of the brain, can be brought on by viral, bacterial and fungal infections, autoimmune diseases, and immunosuppression. Many diseases causing encephalitis are transmitted by mosquitos and ticks. As such, encephalitis is sadly pervasive, affecting more than 4 million people annually worldwide and causing upwards of 150,000 deaths. Symptoms range from mild headaches and nausea to debilitating seizures, hallucinations, and difficulty speaking and remembering. The patient volunteers at the NIH Clinical Center, many of whom are immunocompromised, are at a height...
Source: Videocast - All Events - February 6, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video

National Clinical Care Commission Advisory Committee Meeting - June 2019
The National Clinical Care Advisory Committee evaluates and provides recommendations on the coordination and leveraging of federal programs related to complex metabolic or autoimmune diseases that result from insulin-related issues and represent a significant disease burden in the United States, including complications due to such diseases.Air date: 6/27/2019 8:00:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - June 3, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

Christopher L. Bowlus, MD - Addressing Challenges in the Management of Primary Biliary Cholangitis: Harnessing the Clinical Potential of New Treatment Approaches to Improve Patient Outcomes
Go online to PeerView.com/PST860 to view the activity, download slides and practice aids, and complete the post-test to earn credit. In this activity, an expert in autoimmune liver diseases uses a novel, interactive talk to guide learners through the diagnosis and treatment of primary biliary cholangitis. Upon completion of this activity, participants should be better able to: Incorporate appropriate tests to support the diagnosis of PBC Apply guideline-based recommendations to stratify patients at risk for progressive PBC, Outline current treatment options for PBC in the context of mechanism of action, efficacy, safety, a...
Source: Peerview CME/CE Video Podcast - Internal Medicine International - May 29, 2019 Category: Internal Medicine Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video

2019 Demystifying Medicine Lecture- Autoimmunity: Basic and Clinical Advances and Challenges
Please join us for the next Demystifying Medicine lecture, " Autoimmunity: Basic and Clinical Advances and Challenges, " by Ronald Germain, M.D., Ph.D. (NIAID) and James Katz, M.D. (NIAMS) on April 23 from 4:00 p.m. to 5:30 p.m. in the Building 50 conference room, first floor. CME credit is available. Autoimmunity refers to a system of immune responses gone awry, tantamount to an attack against the body's own healthy cells and tissues with painful and often fatal consequences. This enemy within manifests itself in myriad ways, from targeted attacks (e.g., rheumatoid arthritis leading to debilitating joint damage) to multi...
Source: Videocast - All Events - April 19, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

Autoantigens and autoimmunity: a bedside to bench and back again story
NIH Director's Wednesday Afternoon Lecture Series Noncoding RNAs play critical roles in the metabolism of all cells. The Wolin laboratory studies how noncoding RNAs function, how cells recognize and degrade defective noncoding RNAs, and how failure to degrade these RNAs affects cell function and contributes to human disease. Their studies revealed new mechanisms by which defective RNAs are targeted for degradation and new classes of noncoding RNAs. Most recently, their work has contributed to a novel theory for how the autoimmune disease systemic lupus erythematosus may be triggered in genetically susceptible individuals.A...
Source: Videocast - All Events - February 4, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

Cancer, Autoimmunity and Immunology 2019 (Day 2)
This event will bring together basic research scientists, clinical research scientists and front line physicians who will be discussing the latest immunotherapy breakthroughs in the context or initiation of autoimmune disease. Speakers will cover cancer therapy in the context of existing autoimmunity and the triggering of autoimmunity as a result of the cancer therapy.Air date: 4/16/2019 8:30:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - December 19, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video