Towards a Better Understanding of the Role of the Gut Microbiome in Alzheimer's Disease
This article summarizes research presented at the virtual symposium and workshop, "New Approaches for Understanding the Potential Role of Microbes in Alzheimer's Disease." The objective of these events was to review the evidence base and catalyze research to address knowledge gaps in the hypothesis that infections or microbes play some causative role in the development or progression of Alzheimer's disease. Alzheimer's disease is a complex disease; this symposium was rooted in an understanding that its pathogenesis could be triggered by both microbe-dependent and microbe-independent pathways and the two are not mutually ex...
Source: Fight Aging! - March 15, 2024 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Not the Last of Them
BY KIM BELLARD I’m seeing two conflicting yet connected visions about the future. One is when journalist David Wallace-Wells says we might be in for “golden age for medicine,” with CRISPR and mRNA revolutionizing drug development. The second is the dystopian HBO hit “The Last of Us,” in which a fungal infection has turned much of the world’s population into zombie-like creatures.  The conflict is clear but the connection not so much. Mr. Wallace-Wells never mentions fungi in his article, but if we’re going to have a golden age of medicine, or if we want to avoid a global fungal outbreak, we better be p...
Source: The Health Care Blog - June 27, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Medical Practice Fungal Infections Kim Bellard Medical School Source Type: blogs

Not The Last of Them
By KIM BELLARD I’m seeing two conflicting yet connected visions about the future. One is when journalist David Wallace-Wells says we might be in for “golden age for medicine,” with CRISPR and mRNA revolutionizing drug development. The second is the dystopian HBO hit “The Last of Us,” in which a fungal infection has turned much of the world’s population into zombie-like creatures. The conflict is clear but the connection not so much. Mr. Wallace-Wells never mentions fungi in his article, but if we’re going to have a golden age of medicine, or if we want to avoid a global fungal outbreak, we better be pay...
Source: The Health Care Blog - June 27, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Policy Fungi Golden Age of Medicine Kim Bellard Source Type: blogs

Could aspergillus be hiding out in your critically ill patient?
(Source: Notes from Dr. RW)
Source: Notes from Dr. RW - February 2, 2023 Category: Internal Medicine Tags: critical care infectious disease pulmonary Source Type: blogs

Marijuana Microbe Test in Massachusetts Is Unnecessary and Counterproductive
Jeffrey Miron andRevana SharfuddinStates with legal marijuana typically require lab testing for specific pathogens, such as salmonella and aspergillus. But Massachusetts sets a low limit on the total amount of bacteria and fungus in each regulated unit of marijuana, regardless of whether that fungus or bacteria is harmful.The Boston Globereports:The standards are intended to protect consumers from moldy or bacteria ‐​contaminated flower. But farmers across Massachusetts have complained that the state’s unusually tight rules are based on flimsy science, discourage outdoor growing and other sustainable practices, ...
Source: Cato-at-liberty - March 2, 2021 Category: American Health Authors: Jeffrey Miron, Revana Sharfuddin Source Type: blogs

Tropical Travel Trouble 009 Humongous HIV Extravaganza
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 009 The diagnosis of HIV is no longer fatal and the term AIDS is becoming less frequent. In many countries, people with HIV are living longer than those with diabetes. This post will hopefully teach the basics of a complex disease and demystify some of the potential diseases you need to consider in those who are severely immunosuppressed. While trying to be comprehensive this post can not be exhaustive (as you can imagine any patient with a low ...
Source: Life in the Fast Lane - July 7, 2018 Category: Emergency Medicine Authors: Amanda McConnell Tags: Clinical Cases Tropical Medicine AIDS art cryptococcoma cryptococcus HIV HIV1 HIV2 PEP PrEP TB toxoplasma tuberculoma Source Type: blogs

Funtabulously Frivolous Friday Five 221
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia FFFF…introducing Funtabulously Frivolous Friday Five 220. Question 1 The Adverts, a UK punk band in the 1970s wrote the song “Looking through Gary Gilmore’s eyes”. Who is Gary Gilmore and why would two people be looking through his eyes? + Reveal the Funtabulous Answer expand(document.getElementById('...
Source: Life in the Fast Lane - January 5, 2018 Category: Emergency Medicine Authors: Neil Long Tags: Frivolous Friday Five aspergillum Ayahuasca basket case cornea transplant garlic gary gilmore lone star tick meat allergy otomycosis paul simon shaman swimmers ear Source Type: blogs

Cavernous Sinus Thrombosis: Case Report
Discussion by Dr MGK Murthy, Dr GA Prasad      Cavernous sinus is extradural venous plexus surrounded by a dural fold in the middle cranial fossa containing internal carotid artery with its periarterial sympathetic plexus, abducens nerve lateral to the internal carotid artery, but medial to the oculomotor and trochlear nerves and the ophthalmic and maxillary divisions of the trigeminal nerve, which run superior to inferior within the lateral dural border of the cavernous sinus.     Thrombosis of the cavernous sinus is usually caused by bacterial or fungal invasion comp...
Source: Sumer's Radiology Site - November 14, 2017 Category: Radiology Authors: Sumer Sethi Source Type: blogs

Funtabulously Frivolous Friday Five 205
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia FFFF…introducing Funtabulously Frivolous Friday Five 205. Question 1 Meigs’ Syndrome resolves after removal of the tumour. What is the classic triad of Meigs’ Syndrome? + Reveal the Funtabulous Answer expand(document.getElementById('ddet771338363'));expand(document.getElementById('ddetlink771338363')) The...
Source: Life in the Fast Lane - September 15, 2017 Category: Emergency Medicine Authors: Neil Long Tags: Frivolous Friday Five allergic bronchopulmonary aspergillosis Argyll Robertson aspergilloma aspergillus Calabar extrinsic allergic alveolitis invasive aspergillosis kartagener's syndrome liver Loa loa worms Meigs syndrome ocular oa Source Type: blogs

Direct Alkylation of Amines with Primary and Secondary Alcohols through Biocatalytic Hydrogen Borrowing
AngewchemDirect Alkylation of Amines with Primary and Secondary Alcohols through Biocatalytic Hydrogen Borrowing: The reductive aminase from Aspergillus oryzae (AspRedAm) was combined with a single alcohol dehydrogenase (either metagenomic ADH ‐150, an ADH from Sphingobium yanoikuyae (SyADH), or a variant of the ADH... (Source: Organometallic Current)
Source: Organometallic Current - July 25, 2017 Category: Chemistry Tags: Alkylation Biocatalytic Source Type: blogs

Biosynthesis of Complex Indole Alkaloids: Elucidation of the Concise Pathway of Okaramines
AngewchemBiosynthesis of Complex Indole Alkaloids: Elucidation of the Concise Pathway of Okaramines: The okaramines are a class of complex indole alkaloids isolated from Penicillium and Aspergillus species. Their potent insecticidal activity arises from selectively activating glutamate ‐gated chloride... (Source: Organometallic Current)
Source: Organometallic Current - July 12, 2017 Category: Chemistry Tags: Alkaloids Biosynthesis Source Type: blogs

Aspergillus and Penicillium in the Post-genomic Era review
Excerpt from a book review of Aspergillus and Penicillium in the Post-genomic Era"specialists in the field should definitely take a look at the book" from Biospektrum (2017) 23: 107-108 read more ...Aspergillus and Penicillium in the Post-genomic EraEdited by: Ronald P. de Vries, Isabelle Benoit Gelber and Mikael Rørdam Andersen"new and well-presented book" (IMA Fungus) read more ... (Source: Microbiology Blog: The weblog for microbiologists.)
Source: Microbiology Blog: The weblog for microbiologists. - February 22, 2017 Category: Microbiology Source Type: blogs

Job: Environmental Microbiology – UC Riverside
UC Riverside faculty position in Environmental Microbiology part of Hiring Cluster BREATHE: Environ./Medical Microbiology, Environ./Medical History, Pulmonary Physiology, Pulmonary/Mucosal Immunol Job #JPF00639 School of Medicine – Biomedical Sciences Environmental Microbiology – experience working in natural systems, and in soil and/or air microbial ecology. A range of expertise between bacterial, archaeal, and fungal organisms, is preferred, including aeromicrobiology, and organisms with airborne spores (e.g., Coccidioides, Aspergilli, Pseudomonas, Clostridium, etc.). In addition, the environmental microbiolo...
Source: Fungal Genomes and Comparative Genomics - December 6, 2016 Category: Genetics & Stem Cells Authors: Jason Stajich Tags: jobs aspergillus BREATHE coccidioides microbiology UCRiverside Source Type: blogs

Aspergillus and Penicillium in the Post-genomic Era review
Excerpt from a book review of Aspergillus and Penicillium in the Post-genomic Era"This new and well-presented book gives the impression of a vibrant field and the prospect of an increasingly exciting age of understanding in the biology and physiology of species in these two genera" from IMA Fungus read more ...Aspergillus and Penicillium in the Post-genomic EraEdited by: Ronald P. de Vries, Isabelle Benoit Gelber and Mikael Rørdam AndersenAn essential reference for everyone working with Aspergillus and Penicillium and other filamentous fungi! read more ... (Source: Microbiology Blog: The weblog for microbiologists.)
Source: Microbiology Blog: The weblog for microbiologists. - July 8, 2016 Category: Microbiology Source Type: blogs