Addressing The Threat Of Antibiotic Resistance: Policy Solutions To Fix A Broken Pipeline
Recently, the White House released a major new national strategy to combat antibiotic resistance. As efforts begin to translate that unprecedented announcement into action, it is critical that any strategy to address resistance contain a plan to ensure an adequate antibiotic development pipeline. The overall number of antibiotics reaching the market has declined over time, with 29 and 23 new antibiotics approved in the U.S. in the 1980s and 1990s, respectively, but only nine between 2000 and 2010.
Meanwhile, the evolution of drug-resistance has outpaced the development of new antibiotics. Doctors routinely encounter patien...
Source: Health Affairs Blog - November 6, 2014 Category: Health Management Authors: Rachel Zetts and Allan Coukell Tags: All Categories Pharma Policy Public Health Research Source Type: blogs
Government response to the House of Commons Science and Technology Committee report: ensuring access to working antimicrobials
This report outlines the government response to the House of Commons report on antimicrobial resistance (AMR). It also contains details about the independent review of AMR that the Prime Minister announced on 2 July 2014. The review is working to improve surveillance data and build an international consensus on stimulating the antibiotic market.
Response
DH news (Source: Health Management Specialist Library)
Source: Health Management Specialist Library - September 12, 2014 Category: UK Health Authors: The King's Fund Information & Knowledge Service Tags: Local authorities, public health and health inequalities Source Type: blogs
Advocate Groups Reach Out to President's Science Advisors Ahead of
Antibiotics Meeting | Food Safety News
The President’s Council of Advisors on Science and Technology (PCAST) will meet Friday to discuss its work on antibiotic resistance and nanotechnology and to hear from speakers about oceans policy.A group of public health, consumer, and environmental protection organizations have sent a letter to PCAST expressing concern that the U.S. Food and Drug Administration’s Guidance for Industry #213 and a proposed Veterinary Feed Directive (VFD) rule do not go far enough in addressing antibiotic overuse on farms.By March, FDA had heard from 25 of the 26 drug manufacturers affected by Guidance #213...
Source: PharmaGossip - July 8, 2014 Category: Pharma Commentators Authors: insider Source Type: blogs
Ensuring access to working antimicrobials
This report argues that it is essential that the government puts urgent measures in place to drastically reduce the unnecessary prescription of antibiotics. It also highlights the need for better education of medical students and greater focus on antimicrobial resistance during clinical career development.
Report
Press release (Source: Health Management Specialist Library)
Source: Health Management Specialist Library - July 7, 2014 Category: UK Health Authors: The King's Fund Information & Knowledge Service Tags: Local authorities, public health and health inequalities Workforce and employment Source Type: blogs
UK 5 Year Antimicrobial Resistance (AMR) strategy 2013-2018: measuring success
Department of Health -This guidance outlines measures agreed by the UK antimicrobial resistance strategy High Level Steering Group, based on advice from expert scientific advisory committees including the Advisory Committee on Antimicrobial Resistance and Healthcare Associated Infections (ARHAI). It covers 4 areas: trends in resistance; quality of prescribing in primary and secondary healthcare settings; public and professional knowledge and understanding of antimicrobials and their appropriate use; and global security through ensuring global alignment in addressing AMR. It is aimed at clinical professionals, NHS managers,...
Source: Health Management Specialist Library - June 24, 2014 Category: UK Health Authors: The King's Fund Information & Knowledge Service Tags: Local authorities, public health and health inequalities Source Type: blogs
Pharmacists and GPs complement each other – Keith Ridge
Dr Keith Ridge CBE, the Chief Pharmaceutical Officer for NHS England, gives his views on best practice in action:
One of the privileges of my job is being able to get out and about to see great clinical practice up close.
Last week was one of those opportunities arose when, together with the Chief Executive of the Royal Pharmaceutical Society, Helen Gordon, I spent an enthralling few hours at the Old School Surgery in Fishponds, Bristol.
It’s a modern GP practice with a growing list of 15,000 situated in the heart of the local community.
Two things make the practice a bit different from the norm. Firstly, an independen...
Source: Fade Library - June 10, 2014 Category: Databases & Libraries Authors: NHS England Tags: Chief Pharmaceutical Officer gp Guest blogs Home keith ridge News Pharmacists Source Type: blogs
Antimicrobial resistance: global report on surveillance 2014
This report aims to provide a comprehensive picture of antibiotic resistance across the world, with data from 114 countries. The findings document resistance to antibiotics, especially so-called last resort antibiotics, in all regions of the world. It also shows the gaps in surveillance systems and the need for a standardized approach to tracking and monitoring the issue.
Full report
Summary report
WHO - news (Source: Health Management Specialist Library)
Source: Health Management Specialist Library - April 30, 2014 Category: UK Health Authors: The King's Fund Information & Knowledge Service Tags: Local authorities, public health and health inequalities Source Type: blogs
Advisory committee on antimicrobial resistance and healthcare associated infections: annual reports
Department of Health -The Advisory Committee on Antimicrobial Resistance and Healthcare Associated Infection (ARHAI) have published their annual report which provides a summary of activities carried out by ARHAI between February 2012 to March 2013. The report also includes ARHAI's work plan for 2013 to 2014.
Annual report
Department of Health - publications (Source: Health Management Specialist Library)
Source: Health Management Specialist Library - November 13, 2013 Category: UK Health Authors: The King's Fund Information & Knowledge Service Tags: NHS measurement and performance Patient safety Regulation, governance and accountability Source Type: blogs
The end of antibiotics, period?
Twenty years ago, I wrote a paper for my high school biology class on the not-much-discussed topic of antibiotic resistance. What I learned seemed like science fiction; due to overuse and improper use of antibiotics, we faced a return to the dark ages before penicillin, when a chance infection could easily spell death and doctors were largely helpless in the face of them.
But after writing my essay, life went on. When I got sick, antibiotics were readily available. I remained wary of antibacterial cleansers and other bacteria-bashing products, but essentially, it seemed that I’d been a bit alarmist.
And yet, over the yea...
Source: Open Medicine Blog - - November 8, 2013 Category: Medical Publishers Authors: Carlyn Zwarenstein Source Type: blogs
HHS Issues 2014-2018 Draft Strategic Plan
The U.S. Department of Health and Human Services (HHS) recently published its draft of the Fiscal Year 2014-2018 Strategic plan. Every 4 years, HHS updates its strategic plan, which describes its work to address complex, multifaceted, and ever-evolving health and human service issues, including:
Health Care
Research and Innovation
Prevention and Wellness
An agency strategic plan is one of three main elements required by the Government Performance and Results Act (GPRA) of 1993 (P.L. 103-62) and the GPRA Modernization Act of 2010 (P.L. 111-352). An agency strategic plan defines its mission, goals, and t...
Source: Policy and Medicine - October 14, 2013 Category: Health Medicine and Bioethics Commentators Authors: Thomas Sullivan Source Type: blogs
Continuing Medical Education Courses Decreased Antibiotic Use in Italy
Inappropriate and unnecessary antibiotic prescribing has contributed greatly to a worldwide problem of antimicrobial resistance. Prescribing practices vary widely. In Europe, for example, frequency of antibiotic prescribing differs threefold between countries with the highest and lowest antibiotic use. A similar disparity has been documented in northern and southern regions of Italy.
Italy has one of the highest antibiotic prescribing rates in Europe, however, prescriptions decreased by 5.3% in 2010 following two national information campaigns during the winters of 2009 and 2010.
Systematic reviews have shown that ...
Source: Policy and Medicine - October 3, 2013 Category: Health Medicine and Bioethics Commentators Authors: Thomas Sullivan Source Type: blogs
Mollicutes
Glenn F. Browning and Christine Citti present a new book on Mollicutes: Molecular Biology and Pathogenesis In this book acknowledged experts critically review the most recent advances in the evolution, genetics and molecular pathogenesis of these important pathogens. Topics covered include: taxonomy; genomic mosaics; molecular genetic tools for mollicutes; identification and characterisation of virulence genes in mycoplasmas; post-translational modification of proteins; multifunctional cytoadherence factors; the glycocalyx; glycosidase activity; phase and antigenic variation in mycoplasmas; spiroplasma transmission from i...
Source: Microbiology Blog: The weblog for microbiologists. - May 21, 2013 Category: Microbiology Tags: Microbiology publications Bacteriology publications Molecular Biology publications Genomics publications Source Type: blogs
Death by Infection, the End of Modern Medicine
A post-antibiotic era means, in effect, an end to modern medicine as we know it. Things as common as strep throat or a child’s scratched knee could once again kill.
~ Dr Margaret Chan, Director-General of the World Health Organization
Alzheimer's Reading Room
In its recent annual report on global risks, the World Economic Forum (WEF) concluded that “arguably the greatest risk . . . to human health comes in the form of antibiotic-resistant bacteria. We live in a bacterial world where we will never be able to stay ahead of the mutation curve. A test of our resilience is how far behind the curve we allow ourselves t...
Source: Alzheimer's Reading Room, The - February 10, 2013 Category: Dementia Authors: Bob DeMarco Source Type: blogs
