Multiple Micronutrient Supplementation for Maternal Anemia Prevention in Tanzania ( MMS-MAP ) - MMS vs IFA Trial
Conditions: Pregnancy Related Interventions: Dietary Supplement: Iron Folic Acid Tablets with 60 mg of iron; Dietary Supplement: Multiple Micronutrient Supplements with 60 mg of elemental iron Sponsors: George Washington University; Ifakara Health Institute; Harvard School of Public Health (HSPH); Muhimbili University of Health and Allied Sciences; Africa Academy for Public Health; Columbia University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 6, 2023 Category: Research Source Type: clinical trials

Mobile phone text messaging plus motivational interviewing versus usual care: study protocol for a randomized controlled trial to evaluate effects on breastfeeding, child health, and survival outcomes, among women living with HIV (MTI-MI)
DiscussionThe study findings may facilitate decision-making on (1) whether implementation of the breastfeeding policy achieved the desired outcomes, (2) interventions needed to sustain breastfeeding, and (3) whether the interventions do have an impact on child health.Trial registrationClinicalTrials.gov NCT05063240. Pan African Clinical Trial Registry PACTR202110870407786. Oct. 1, 2021. (Source: Trials)
Source: Trials - October 5, 2023 Category: Research Source Type: clinical trials

Community-based management of a five-arm randomised clinical trial in COVID-19 outpatients in South Africa: challenges and opportunities
ConclusionCompleting a COVID-19 trial in outpatients during the height of the pandemic required multiple innovations in nearly every aspect of clinical trial management, a high commitment level from study staff and patients, and support from study sponsors. Our experience has generated a more robust clinical research infrastructure, building in efficiencies to clinical trial management beyond the pandemic. (Source: Trials)
Source: Trials - October 4, 2023 Category: Research Source Type: clinical trials

Pair 2 Care: Peer Support for Caregivers of African Americans Living With Dementia
Conditions: Family Caregiver; Dementia; Peer Support Interventions: Behavioral: Peer Support Sponsors: Ohio State University; Cambia Health Foundation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 3, 2023 Category: Research Source Type: clinical trials

The African Critical Illness Outcomes Study
Conditions:   Critical Illness;   Mortality Intervention:   Sponsors:   University of Cape Town;   Muhimbili University of Health and Allied Sciences Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 25, 2023 Category: Research Source Type: clinical trials

The African Critical Illness Outcomes Study
Conditions: Critical Illness; Mortality Sponsors: University of Cape Town; Muhimbili University of Health and Allied Sciences Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 25, 2023 Category: Research Source Type: clinical trials

First-in-Human Trial of the Novel Tuberculosis Vaccine Candidate, H107/CAF ®10b
Condition:   Healthy Interventions:   Biological: H107e;   Biological: CAF®10b;   Biological: H107e/CAF®10b - low adjuvant dose;   Biological: H107e/CAF®10b - full adjuvant dose;   Biological: Low dose intranasal H107e;   Biological: Full dose intranasal H107e;   Biological: H107e/CAF®10b;   Biologica l: i.m. placebo;   Biological: BCG;   Biological: i.d. placebo;   Biological: Intranasal H107e Sponsors:   Statens Serum Institut;   Aurum Institute;   Bill and Melinda Gates Foundation;   Leiden University Medical Center;   South African Tuberculosis Vaccine Init...
Source: ClinicalTrials.gov - September 22, 2023 Category: Research Source Type: clinical trials