Haem iron versus ferrous iron salts to treat iron deficiency anaemia in Gambian children: protocol for randomised controlled trial {1}
This study aims to compare da ily supplementation with haem iron versus ferrous sulphate on haemoglobin concentration and serum ferritin concentration after 12 weeks of supplementation.MethodsThis will be a two-arm, randomised controlled trial. Gambian children aged 6 –12 months with anaemia will be recruited within a predefined geographical area and recruited by trained field workers. Eligible participants will be individually randomised using a 1:1 ratio within permuted blocks to daily supplementation for 12 weeks with either 10.0 mg of elemental iron as haem or ferrous sulphate. Safety outcomes such as diarrhoea and i...
Source: Trials - April 19, 2024 Category: Research Source Type: clinical trials
Building Community Health Volunteers' Capacity to Support Parents With Young Children With SafeCare Kenya
Conditions: Child Maltreatment; Parenting Interventions: Behavioral: SafeCare Kenya; Other: Care as Usual by Community Health Volunteers Sponsors: Pacific University; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); Africa Mental Health Research and Training Foundation; Georgia State University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials
COVID Quick Start - Test and Treat in Africa
Conditions: COVID-19 Sponsors: Duke University; Duke Clinical Research Institute; Clinton Health Access Initiative, Nigeria Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 11, 2024 Category: Research Source Type: clinical trials
Impact of the Financial Inclusion Improves Sanitation and Health
Conditions: Health Knowledge, Attitudes, Practice Interventions: Behavioral: Financial Inclusion Improves Sanitation and Health Sponsors: Amref Health Africa Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 10, 2024 Category: Research Source Type: clinical trials
Stop Transmission of Gambiense Human African Trypanosomiasis (STROgHAT)
Conditions: Human African Trypanosomiasis Interventions: Drug: Treatment of seropositive individuals (positive serology test, but parasitology not confirmed) Sponsors: Drugs for Neglected Diseases; Institute of Tropical Medicine, Belgium; Institut de Recherche pour le Developpement; Institut National de Recherche Biom édicale. Kinshasa, République Démocratique du Congo; Ministry of Public Health, Democratic Republic of the Congo Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 10, 2024 Category: Research Source Type: clinical trials
Adapting a Low-cost Intimate Partner Violence and Mental Health Response Intervention
Conditions: Violence, Domestic; Psychological Distress Interventions: Behavioral: WINGS+PM+; Behavioral: PM+-only Sponsors: Columbia University; Drexel University; Africa Mental Health Research and Training Foundation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 5, 2024 Category: Research Source Type: clinical trials
HTN App for HTN Control and Cardiovascular Health Among African-Americans
Conditions: Hypertension Interventions: Behavioral: FAITH! HTN app Sponsors: Mayo Clinic; Miami Heart Research Institute Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 4, 2024 Category: Research Source Type: clinical trials
A pragmatic randomized controlled trial to evaluate the efficacy and safety of an oral short-course regimen including bedaquiline for the treatment of patients with multidrug-resistant tuberculosis in China: study protocol for PROSPECT
DiscussionPROSPECT aims to assess the safety and efficacy of a BDQ-containing SCR MDR-TB treatment at seventeen sites across China, while also providing high-quality data to guide SCRs administration under the direction of the China National Tuberculosis Program for MDR-TB. Additionally, PROSPECT will explore the potential benefits of extending the administration of the 9-month BDQ-containing SCR for participants without sputum conversion by week 16.Trial registrationClinicalTrials.gov NCT05306223. Prospectively registered on 16 March 2022 athttps://clinicaltrials.gov/ct2/show/NCT05306223?term=NCT05306223&draw=1&ra...
Source: Trials - April 1, 2024 Category: Research Source Type: clinical trials
Electronic Diabetes Tune-Up Group (eDTU) for African Americans
Conditions: Diabetes Mellitus, Type 2; Diabetes Complications Interventions: Behavioral: Diabetes Tune-Up Group Sponsors: Indiana University; Indiana University Health Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 20, 2024 Category: Research Source Type: clinical trials
Systems Analysis and Improvement Approach to Prevent TB
Conditions: Tuberculosis; TPT; TB - Tuberculosis Interventions: Other: Systems Analysis and Improvement Approach for TB (SAIA-TB) Sponsors: Boston College; National Institutes of Health (NIH); Boston University; University of Washington; Medical Research Council, South Africa; National Institute of Nursing Research (NINR) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 18, 2024 Category: Research Source Type: clinical trials
Brief Transdiagnostic Treatment for Anxiety Disorders and Post-traumatic Stress Disorder (PTSD) in South Africa: A Hybrid-Effectiveness Trial
Conditions: Anxiety Disorders; Post-traumatic Stress Disorder Interventions: Behavioral: False Safety Behavioral Elimination Treatment (FSET); Behavioral: Enhanced Standard Care Sponsors: Harvard Medical School (HMS and HSDM); University of Stellenbosch; Fogarty International Center of the National Institute of Health; Massachusetts General Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 4, 2024 Category: Research Source Type: clinical trials
Joint Patient and Caregiver Intervention for Older African Americans With Type 2 Diabetes
Conditions: Type 2 Diabetes Interventions: Behavioral: Joint Home-DM-BAT Intervention; Behavioral: Usual Care Sponsors: Medical College of Wisconsin Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials
Efficacy of chlorfenapyr-pyrethroid and piperonyl butoxide-pyrethroid long-lasting insecticidal nets (LLINs) compared to pyrethroid-only LLINs for malaria control in C ôte d’Ivoire: a three group, cluster randomised trial
This study conducted in C ôte d’Ivoire will evaluate the efficacy on epidemiological and entomological outcomes of (1) the control arm: MAGNet® LN, which contains the pyrethroid, alpha-cypermethrin, (2) VEERALIN® LN, a net combining the synergist PBO and alpha-cypermethrin, and (3) Interceptor® G2 LN, which incorporate s chlorfenapyr and alpha-cypermethrin, two adulticides with different mechanisms of action. A total of 33 villages with an average of 200 households per village will be identified, mapped, and randomised in a ratio of 1:1:1. Nets will be distributed at a central point following national guidelines w it...
Source: Trials - February 28, 2024 Category: Research Source Type: clinical trials
Improved Access to Quality Care and Healthcare Use
Conditions: Health Care Utilization; Health Knowledge, Attitudes, Practice; Health, Subjective Interventions: Other: Free high-quality care; Other: Close distance; Other: Far distance Sponsors: London School of Economics and Political Science; University of Witwatersrand, South Africa Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 23, 2024 Category: Research Source Type: clinical trials
Project Phakama: Testing Support Strategies to Empower Young Women on PrEP in South Africa
Conditions: Pre-exposure Prophylaxis; HIV Infections Interventions: Behavioral: Case management; Behavioral: Food vouchers; Behavioral: PrEP support buddy; Behavioral: Community-based PrEP pickup points Sponsors: Johns Hopkins Bloomberg School of Public Health; TB/HIV Care; Unity Health Toronto; National Institute of Mental Health (NIMH) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 23, 2024 Category: Research Source Type: clinical trials
