'Information theory' recruited to help scientists find cancer genes
(Johns Hopkins Medicine) Using a widely known field of mathematics designed mainly to study how digital and other forms of information are measured, stored and shared, scientists at Johns Hopkins Medicine and Johns Hopkins Kimmel Cancer Center say they have uncovered a likely key genetic culprit in the development of acute lymphoblastic leukemia (ALL). (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 20, 2021 Category: Cancer & Oncology Source Type: news
Curis Receives FDA Orphan Drug Designation for CA-4948 for the Treatment of AML and MDS
LEXINGTON, Mass., April 19, 2021 -- (Healthcare Sales & Marketing Network) -- Curis, Inc. (NASDAQ: CRIS), a biotechnology company focused on the development of innovative therapeutics for the treatment of cancer, is pleased to announce that the U.S. Food ... Biopharmaceuticals, Oncology, FDA Curis, acute myeloid leukemia, myelodysplastic syndromes (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - April 19, 2021 Category: Pharmaceuticals Source Type: news
Scientists identify potential drug candidates for deadly pediatric leukemia
(Sanford Burnham Prebys Medical Discovery Institute) Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that two existing drug candidates--JAK inhibitors and Mepron--hold potential as treatments for a deadly acute myeloid leukemia (AML) subtype that is more common in children. The foundational study, published in the journal Blood, is a first step toward finding effective treatments for the hard-to-treat blood cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 14, 2021 Category: Cancer & Oncology Source Type: news
Diet, Exercise Intervention Explored in Children With B-ALL
THURSDAY, April 8, 2021 -- For children with B-cell acute lymphoblastic leukemia (B-ALL), a diet and exercise intervention might improve disease response, according to a study published online April 1 in Blood Advances.
Etan Orgel, M.D., from the... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 8, 2021 Category: Pharmaceuticals Source Type: news
What are the risk factors for experiencing side effects from childhood cancer treatments?
(Wiley) Steroids are essential for treating children with acute lymphoblastic leukemia, a type of cancer of the blood and bone marrow, but they can cause severe side effects such as psychological reactions and sleep problems. An analysis published in Psycho-Oncology of all relevant studies published to date indicates that there's insufficient high-quality research investigating the risk factors for these side effects. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 7, 2021 Category: International Medicine & Public Health Source Type: news
Adding in Stem Cell Therapy Helps Beat a Common Childhood Leukemia
FRIDAY, April 2, 2021 -- Combining stem cell transplants with cutting-edge immunotherapy prevents leukemia relapses in young people and improves their chances of survival, new research suggests.
Acute lymphoblastic leukemia is the most common... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - April 2, 2021 Category: General Medicine Source Type: news
Low-calorie diet and mild exercise improve survival for young people with leukemia
In some cancers, including leukemia in children and adolescents, obesity can negatively affect survival outcomes. Obese young people with leukemia are 50% more likely to relapse after treatment than their lean counterparts.Now,a study led by researchers at UCLA and Children’s Hospital Los Angeles has shown that a combination of modest dietary changes and exercise can dramatically improve survival outcomes for those with acute lymphoblastic leukemia, the most common childhood cancer.The researchers found that patients who reduced their calorie intake by 10% or more and adopted a moderate exercise program immediately aft...
Source: UCLA Newsroom: Health Sciences - April 1, 2021 Category: Universities & Medical Training Source Type: news
Stem cell transplants prevent relapses of most common childhood cancer
(University of Virginia Health System) Children and young adults who receive CAR T-cell therapy for the most common childhood cancer - acute lymphoblastic leukemia - suffer remarkably fewer relapses and are far more likely to survive when the treatment is paired with a subsequent stem cell transplant, a new study finds. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 1, 2021 Category: Cancer & Oncology Source Type: news
Low-calorie diet and mild exercise improve survival for young people with leukemia
(University of California - Los Angeles Health Sciences) A study led by researchers at UCLA and CHLA has shown that a combination of modest dietary changes and exercise can dramatically improve survival outcomes for those with acute lymphoblastic leukemia, the most common childhood cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 1, 2021 Category: Cancer & Oncology Source Type: news
Crnic Institute discovery may explain high risk of leukemia in children with Down syndrome
(University of Colorado Anschutz Medical Campus) Children with Down syndrome are 20-times more likely to develop acute lymphocytic leukemia (ALL) and 150-times more likely to develop acute myeloid leukemia (AML) compared to their typical peers. According to a new study by researchers at the Linda Crnic Institute for Down Syndrome, the reason could be that children with Down syndrome are more likely to present with clonal hematopoiesis (CH), a process in which a blood stem cell acquires a genetic mutation that promotes replication. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 31, 2021 Category: International Medicine & Public Health Source Type: news
Jazz Pharmaceuticals Announces FDA Approval of Additional Indication for Vyxeos (daunorubicin and cytarabine) for the Treatment of Secondary Acute Myeloid Leukemia in Pediatric Patients
DUBLIN, March 30, 2021 /PRNewswire/ -- Jazz Pharmaceuticals plc (Nasdaq: JAZZ) today announced that the U.S. Food and Drug Administration (FDA) approved a revised label for Vyxeos® (daunorubicin and cytarabine) to... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - March 30, 2021 Category: Drugs & Pharmacology Source Type: news
Consumer Health: Treating acute lymphocytic leukemia
Acute lymphocytic leukemia is a cancer of the blood and bone marrow. It's the most common type of cancer in children, and treatment results in a good chance for a cure. Acute lymphocytic leukemia also can occur in adults, though the chance of a cure is reduced greatly. Signs and symptoms of acute lymphocytic leukemia [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - March 29, 2021 Category: Databases & Libraries Source Type: news
Risk Factors Predict Graft Failure in Pediatric Acute Leukemia Patients Risk Factors Predict Graft Failure in Pediatric Acute Leukemia Patients
Researchers have developed a predictive score for the risk of graft failure in patients with acute leukemia who undergo allogeneic hematopoietic stem cell transplantation with ex vivo T-cell depletion.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 25, 2021 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
Virginia Commonwealth University Scientists Combine dPCR and High-Speed Microscopic Imaging to Reduce Cost of Diagnosing Cancers
VCU scientists used the technique to measure mutations associated with acute myeloid leukemia, potentially offering an attractive alternative to DNA sequencing More accurate but less-costly cancer diagnostics are the Holy Grail of cancer research. Now, research scientists at Virginia Commonwealth University (VCU) say they have developed a clinical laboratory diagnostic technique that could be far […]
The post Virginia Commonwealth University Scientists Combine dPCR and High-Speed Microscopic Imaging to Reduce Cost of Diagnosing Cancers appeared first on Dark Daily. (Source: Dark Daily)
Source: Dark Daily - March 24, 2021 Category: Laboratory Medicine Authors: Jude Tags: Digital Pathology Instruments & Equipment Laboratory Instruments & Laboratory Equipment Laboratory Management and Operations Laboratory Operations Laboratory Pathology Laboratory Testing Management & Operations ACS Alden Chesney MD ame Source Type: news
Drug Trial Snapshot: DAURISMO
DAURISMO is used to treat adults with newly-diagnosed acute myeloid leukemia (AML).
It is to be used in patients who•are 75 years of age or older, or•have other medical conditions that prevent the use of standard chemotherapy.
AML is a rapidly progressing cancer that forms in the bone marrow and (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - March 18, 2021 Category: Drugs & Pharmacology Authors: FDA Source Type: news
