Part 2 – Coronary angiography with gadofosveset trisodium: a prospective intra-subject comparison for dose optimization for 100 % efficiency imaging
Three tesla (3T) coronary magnetic resonance angiography (MRA) may be optimized using gadolinium-based contrast agents (GBCA) such as gadofosveset trisodium. The goal of this study was to evaluate if there is ... (Source: BMC Cardiovascular Disorders)
Source: BMC Cardiovascular Disorders - March 22, 2016 Category: Cardiology Authors: Mark A. Ahlman, Fabio S. Raman, Jianing Pang, Filip Zemrak, Veit Sandfort, Scott R. Penzak, Zhaoyang Fan, Songtao Liu, Debiao Li and David A. Bluemke Source Type: research
Time-resolved contrast-enhanced MRA (TWIST) with gadofosveset trisodium in the classification of soft-tissue vascular anomalies in the head and neck in children following updated 2014 ISSVA classification: first report on systematic evaluation of MRI and TWIST in a cohort of 47 children
To evaluate the relative accuracy of contrast-enhanced time-resolved angiography with interleaved stochastic trajectories versus conventional contrast-enhanced magnetic resonance imaging (MRI) following International Society for the Study of Vascular Anomalies updated 2014-based classification of soft-tissue vascular anomalies in the head and neck in children. (Source: Clinical Radiology)
Source: Clinical Radiology - October 13, 2015 Category: Radiology Authors: L.J. Higgins, J. Koshy, S.E. Mitchell, C.R. Weiss, K.A. Carson, T.A.G.M. Huisman, A. Tekes Source Type: research
Gadofosveset Trisodium–Enhanced MR Angiography for Detection of Lower Gastrointestinal Bleeding
The purpose of our study is to determine if Gadofosveset trisodium enhanced MRA could be used for detection and localization of acute LGI bleed. Four patients underwent MRA (4F, mean 65y) for suspected LGIB. MRA detected an active rectal bleed in 1 patient. All other patients did not demonstrate active bleeding and these true negatives were confirmed by CTA, endoscopy and tagged-RBC scan or DSA. Preliminary results suggest that MRA may serve as an alternative technique for detecting acute LGIB when nuclear scintigraphy is unavailable or in the younger radiosensitive population but further investigation in a larger cohort i...
Source: Clinical Imaging - August 12, 2015 Category: Radiology Authors: Robert F Hanna, William F Browne, Lauren G Khanna, Martin R Prince, Elizabeth M Hecht Tags: Original Research Source Type: research
Equilibrium‐phase MR angiography: Comparison of unspecific extracellular and protein‐binding gadolinium‐based contrast media with respect to image quality
The purpose of this study was to compare contrast and image quality of whole‐body equilibrium‐phase high‐spatial‐resolution MR angiography using a non‐protein‐binding unspecific extracellular gadolinium‐based contrast medium with that of two contrast media with different protein‐binding properties. 45 patients were examined using either 15 mL of gadobutrol (non‐protein‐binding, n = 15), 32 mL of gadobenate dimeglumine (weakly protein binding, n = 15) or 11 mL gadofosveset trisodium (protein binding, n = 15) followed by equilibrium‐phase high‐spatial‐resolution MR‐angiography of four ...
Source: Contrast Media and Molecular Imaging - August 11, 2015 Category: Radiology Authors: Katharina Erb‐Eigner, Matthias Taupitz, Patrick Asbach Tags: Full paper Source Type: research
Abdominal Vasculature in Dynamic Contrast-enhanced Liver MRI at 3.0T: An Intraindividual Comparative Study Using Gadoxetate Disodium and Gadofosveset Trisodium
To intraindividually compare gadoxetate disodium and gadofosveset trisodium regarding vessel contrast, image quality and vessel delineation in dynamic contrast-enhanced liver MRI at 3.0T. (Source: Magnetic Resonance Imaging)
Source: Magnetic Resonance Imaging - August 10, 2015 Category: Radiology Authors: Patrick A. Kupczyk, Winfried A. Willinek, Dariusch R. Hadizadeh, Frank Traeber, Juergen Gieseke, Carsten Meyer, Hans H. Schild, Guido M. Kukuk Tags: Original Contribution Source Type: research
Combined gadoxetic acid and gadofosveset enhanced liver MRI: A feasibility and parameter optimization study.
CONCLUSION: Combined gadoxetic acid and gadofosveset enhanced liver MRI is feasible, with low flip angles minimizing contrast between vessels and liver. Further clinical studies are needed to confirm that low flip angles provide an optimal combination of sensitivity and specificity for lesion detection in patients. Magn Reson Med, 2015. © 2015 Wiley Periodicals, Inc.
PMID: 25648403 [PubMed - as supplied by publisher] (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - February 3, 2015 Category: Radiology Authors: Bannas P, Motosugi U, Hernando D, Rahimi MS, Holmes JH, Reeder SB Tags: Magn Reson Med Source Type: research
Combined gadoxetic acid and gadofosveset enhanced liver MRI: A feasibility and parameter optimization study
ConclusionCombined gadoxetic acid and gadofosveset enhanced liver MRI is feasible, with low flip angles minimizing contrast between vessels and liver. Further clinical studies are needed to confirm that low flip angles provide an optimal combination of sensitivity and specificity for lesion detection in patients. Magn Reson Med, 2015. © 2015 Wiley Periodicals, Inc. (Source: Magnetic Resonance in Medicine)
Source: Magnetic Resonance in Medicine - February 3, 2015 Category: Radiology Authors: Peter Bannas, Utaroh Motosugi, Diego Hernando, Mahdi Salmani Rahimi, James H. Holmes, Scott B. Reeder Tags: Full Paper Source Type: research
Adverse allergic reactions to linear ionic gadolinium-based contrast agents: experience with 194, 400 injections
To report the authors' experience with the administration of four gadolinium-based contrast agents (GBCA; gadopentetate dimeglumine, gadofosveset trisodium, gadoxetate disodium and gadobenate dimeglumine) in a large study population at a single, large academic medical centre. (Source: Clinical Radiology)
Source: Clinical Radiology - January 24, 2015 Category: Radiology Authors: S. Aran, K.W. Shaqdan, H.H. Abujudeh Source Type: research
Blood Pool Contrast-enhanced Magnetic Resonance Angiography with Correlation to Digital Subtraction Angiography: A Pictorial Review
Martha-Grace Knuttinen, Jillian Karow, Winnie Mar, Margaret Golden, Karen L XieJournal of Clinical Imaging Science 2014 4(1):63-63Magnetic resonance angiography (MRA) provides noninvasive visualization of the vascular supply of soft tissue masses and vascular pathology, without harmful radiation. This is important for planning an endovascular intervention, and helps to evaluate the efficiency and effectiveness of the treatment. MRA with conventional extracellular contrast agents relies on accurate contrast bolus timing, limiting the imaging window to first-pass arterial phase. The recently introduced blood pool contrast ag...
Source: Journal of Clinical Imaging Science - November 29, 2014 Category: Radiology Authors: Martha-Grace KnuttinenJillian KarowWinnie MarMargaret GoldenKaren L Xie Source Type: research
Extracardiac applications of MR blood pool contrast agent in children
Abstract
Magnetic resonance (MR) angiography has significantly reduced the need for diagnostic conventional angiography and is preferred over CT angiography in children because of its lack of ionizing radiation. The availability of gadofosveset trisodium (the only clinically approved blood pool MR contrast agent) has led to an increase in applications of MR for vascular imaging and an improvement in diagnostic quality of MR angiography. Gadofosveset is a gadolinium-based contrast agent that binds reversibly to albumin, resulting in increased paramagnetic effect and longer intravascular residence. This a...
Source: Pediatric Radiology - November 20, 2014 Category: Radiology Source Type: research
2D phase contrast blood flow velocity measurements of the thoracic vasculature: comparison of the effect of gadofosveset trisodium and gadopentetate dimeglumine
This study was approved by the ethics committee (Study-Number-07/Q0704/2) and registered with the MedicinesAndHealthcareProductsRegulatoryAgency (MHRA-Study-Number-28482/0002/001-0001, EudraCT-Number-2006-007042). All patients signed an informed consent. 20 patients were examined using a 1.5T MR-scanner and 32-channel-coil-technology. Gadopentetate-dimeglumine (GdD) and gadofosveset-trisodium (GdT) were administered in the same patient on consecutive days. Image quality, velocity-to-noise-ratios (VNRs) and standard-deviation of blood-flow-velocities (phase-noise) were compared between GdT, GdD and non-contrast-enhanced ima...
Source: The International Journal of Cardiovascular Imaging - November 11, 2014 Category: Radiology Source Type: research
Tumor‐induced alterations in lymph node lymph drainage identified by contrast‐enhanced MRI
Conclusion3.0T MRI lymphography using Gd‐FVT identified several distinctive alterations in the uptake of contrast agent into TDLNs, which could be useful to identify the correct TDLN, and to characterize TDLN lymphatic sinus growth that may predict metastatic potential.J. Magn. Reson. Imaging 2014. © 2014 Wiley Periodicals, Inc. (Source: Journal of Magnetic Resonance Imaging)
Source: Journal of Magnetic Resonance Imaging - September 25, 2014 Category: Radiology Authors: Alanna Ruddell, Sara B. Kirschbaum, Sheila N. Ganti, Cheng‐Liang Liu, Ryan R. Sun, Savannah C. Partridge Tags: Original Research Source Type: research
Magnetic Resonance Lymphography of the Thoracic Duct after Interstitial Injection of Gadofosveset Trisodium: A Pilot Dosing Study in a Porcine Model
Lymphatic Research and Biology , Vol. 0, No. 0. (Source: Lymphatic Research and Biology)
Source: Lymphatic Research and Biology - February 6, 2014 Category: Biology Tags: article Source Type: research
Contrast enhanced MR venography with gadofosveset trisodium: Evaluation of the intracranial and extracranial venous system
ConclusionCEMRV using gadofosveset trisodium is accurate in the evaluation of the venous system. J. Magn. Reson. Imaging 2013;. © 2013 Wiley Periodicals, Inc. (Source: Journal of Magnetic Resonance Imaging)
Source: Journal of Magnetic Resonance Imaging - November 22, 2013 Category: Radiology Authors: Larry A. Kramer, Alan M. Cohen, Khader M. Hasan, Jared H. Heimbigner, Andrew D. Barreto, Staley A. Brod, Ponnada A. Narayana, Jerry S. Wolinsky Tags: Original Research Source Type: research
