Exstrophy-Epispadias Complex
Urol Clin North Am. 2023 Aug;50(3):403-414. doi: 10.1016/j.ucl.2023.04.004. Epub 2023 May 19.ABSTRACTExstrophy-epispadias complex encompasses a spectrum of disorders with lower abdominal midline malformations, including epispadias, bladder exstrophy, and cloacal exstrophy, also known as Omphalocele-Exstrophy-Imperforate Anus-Spinal Anomalies Complex. In this review, the authors discuss the epidemiology, embryologic cause, prenatal findings, phenotypic characteristics, and management strategies of these 3 conditions. The primary focus is to summarize outcomes pertaining to each condition.PMID:37385703 | DOI:10.1016/j.ucl.20...
Source: The Urologic Clinics of North America - June 29, 2023 Category: Urology & Nephrology Authors: Ted Lee Joseph Borer Source Type: research
Exstrophy-Epispadias Complex
Urol Clin North Am. 2023 Aug;50(3):403-414. doi: 10.1016/j.ucl.2023.04.004. Epub 2023 May 19.ABSTRACTExstrophy-epispadias complex encompasses a spectrum of disorders with lower abdominal midline malformations, including epispadias, bladder exstrophy, and cloacal exstrophy, also known as Omphalocele-Exstrophy-Imperforate Anus-Spinal Anomalies Complex. In this review, the authors discuss the epidemiology, embryologic cause, prenatal findings, phenotypic characteristics, and management strategies of these 3 conditions. The primary focus is to summarize outcomes pertaining to each condition.PMID:37385703 | DOI:10.1016/j.ucl.20...
Source: The Urologic Clinics of North America - June 29, 2023 Category: Urology & Nephrology Authors: Ted Lee Joseph Borer Source Type: research
Exstrophy-Epispadias Complex
Urol Clin North Am. 2023 Aug;50(3):403-414. doi: 10.1016/j.ucl.2023.04.004. Epub 2023 May 19.ABSTRACTExstrophy-epispadias complex encompasses a spectrum of disorders with lower abdominal midline malformations, including epispadias, bladder exstrophy, and cloacal exstrophy, also known as Omphalocele-Exstrophy-Imperforate Anus-Spinal Anomalies Complex. In this review, the authors discuss the epidemiology, embryologic cause, prenatal findings, phenotypic characteristics, and management strategies of these 3 conditions. The primary focus is to summarize outcomes pertaining to each condition.PMID:37385703 | DOI:10.1016/j.ucl.20...
Source: The Urologic Clinics of North America - June 29, 2023 Category: Urology & Nephrology Authors: Ted Lee Joseph Borer Source Type: research
Exstrophy-Epispadias Complex
Urol Clin North Am. 2023 Aug;50(3):403-414. doi: 10.1016/j.ucl.2023.04.004. Epub 2023 May 19.ABSTRACTExstrophy-epispadias complex encompasses a spectrum of disorders with lower abdominal midline malformations, including epispadias, bladder exstrophy, and cloacal exstrophy, also known as Omphalocele-Exstrophy-Imperforate Anus-Spinal Anomalies Complex. In this review, the authors discuss the epidemiology, embryologic cause, prenatal findings, phenotypic characteristics, and management strategies of these 3 conditions. The primary focus is to summarize outcomes pertaining to each condition.PMID:37385703 | DOI:10.1016/j.ucl.20...
Source: The Urologic Clinics of North America - June 29, 2023 Category: Urology & Nephrology Authors: Ted Lee Joseph Borer Source Type: research
Exstrophy-Epispadias Complex
Urol Clin North Am. 2023 Aug;50(3):403-414. doi: 10.1016/j.ucl.2023.04.004. Epub 2023 May 19.ABSTRACTExstrophy-epispadias complex encompasses a spectrum of disorders with lower abdominal midline malformations, including epispadias, bladder exstrophy, and cloacal exstrophy, also known as Omphalocele-Exstrophy-Imperforate Anus-Spinal Anomalies Complex. In this review, the authors discuss the epidemiology, embryologic cause, prenatal findings, phenotypic characteristics, and management strategies of these 3 conditions. The primary focus is to summarize outcomes pertaining to each condition.PMID:37385703 | DOI:10.1016/j.ucl.20...
Source: The Urologic Clinics of North America - June 29, 2023 Category: Urology & Nephrology Authors: Ted Lee Joseph Borer Source Type: research
Exstrophy-Epispadias Complex
Urol Clin North Am. 2023 Aug;50(3):403-414. doi: 10.1016/j.ucl.2023.04.004. Epub 2023 May 19.ABSTRACTExstrophy-epispadias complex encompasses a spectrum of disorders with lower abdominal midline malformations, including epispadias, bladder exstrophy, and cloacal exstrophy, also known as Omphalocele-Exstrophy-Imperforate Anus-Spinal Anomalies Complex. In this review, the authors discuss the epidemiology, embryologic cause, prenatal findings, phenotypic characteristics, and management strategies of these 3 conditions. The primary focus is to summarize outcomes pertaining to each condition.PMID:37385703 | DOI:10.1016/j.ucl.20...
Source: The Urologic Clinics of North America - June 29, 2023 Category: Urology & Nephrology Authors: Ted Lee Joseph Borer Source Type: research
Exstrophy-Epispadias Complex
Urol Clin North Am. 2023 Aug;50(3):403-414. doi: 10.1016/j.ucl.2023.04.004. Epub 2023 May 19.ABSTRACTExstrophy-epispadias complex encompasses a spectrum of disorders with lower abdominal midline malformations, including epispadias, bladder exstrophy, and cloacal exstrophy, also known as Omphalocele-Exstrophy-Imperforate Anus-Spinal Anomalies Complex. In this review, the authors discuss the epidemiology, embryologic cause, prenatal findings, phenotypic characteristics, and management strategies of these 3 conditions. The primary focus is to summarize outcomes pertaining to each condition.PMID:37385703 | DOI:10.1016/j.ucl.20...
Source: The Urologic Clinics of North America - June 29, 2023 Category: Urology & Nephrology Authors: Ted Lee Joseph Borer Source Type: research
Exstrophy-Epispadias Complex
Urol Clin North Am. 2023 Aug;50(3):403-414. doi: 10.1016/j.ucl.2023.04.004. Epub 2023 May 19.ABSTRACTExstrophy-epispadias complex encompasses a spectrum of disorders with lower abdominal midline malformations, including epispadias, bladder exstrophy, and cloacal exstrophy, also known as Omphalocele-Exstrophy-Imperforate Anus-Spinal Anomalies Complex. In this review, the authors discuss the epidemiology, embryologic cause, prenatal findings, phenotypic characteristics, and management strategies of these 3 conditions. The primary focus is to summarize outcomes pertaining to each condition.PMID:37385703 | DOI:10.1016/j.ucl.20...
Source: The Urologic Clinics of North America - June 29, 2023 Category: Urology & Nephrology Authors: Ted Lee Joseph Borer Source Type: research
Exstrophy-Epispadias Complex
Urol Clin North Am. 2023 Aug;50(3):403-414. doi: 10.1016/j.ucl.2023.04.004. Epub 2023 May 19.ABSTRACTExstrophy-epispadias complex encompasses a spectrum of disorders with lower abdominal midline malformations, including epispadias, bladder exstrophy, and cloacal exstrophy, also known as Omphalocele-Exstrophy-Imperforate Anus-Spinal Anomalies Complex. In this review, the authors discuss the epidemiology, embryologic cause, prenatal findings, phenotypic characteristics, and management strategies of these 3 conditions. The primary focus is to summarize outcomes pertaining to each condition.PMID:37385703 | DOI:10.1016/j.ucl.20...
Source: The Urologic Clinics of North America - June 29, 2023 Category: Urology & Nephrology Authors: Ted Lee Joseph Borer Source Type: research
SPECC1L: a cytoskeletal protein that regulates embryonic tissue dynamics
Biochem Soc Trans. 2023 Jun 22:BST20220461. doi: 10.1042/BST20220461. Online ahead of print.ABSTRACTMany structural birth defects occur due to failure of tissue movement and fusion events during embryogenesis. Examples of such birth defects include failure of closure of the neural tube, palate, and ventral body wall. Actomyosin forces play a pivotal role in these closure processes, making proteins that regulate actomyosin dynamics a priority when studying the etiology of structural birth defects. SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1 like) cytoskeletal protein associates with microtubules,...
Source: Biochemical Society Transactions - June 22, 2023 Category: Biochemistry Authors: Irfan Saadi Jeremy P Goering Brittany M Hufft-Martinez Pamela V Tran Source Type: research
SPECC1L: a cytoskeletal protein that regulates embryonic tissue dynamics
Biochem Soc Trans. 2023 Jun 22:BST20220461. doi: 10.1042/BST20220461. Online ahead of print.ABSTRACTMany structural birth defects occur due to failure of tissue movement and fusion events during embryogenesis. Examples of such birth defects include failure of closure of the neural tube, palate, and ventral body wall. Actomyosin forces play a pivotal role in these closure processes, making proteins that regulate actomyosin dynamics a priority when studying the etiology of structural birth defects. SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1 like) cytoskeletal protein associates with microtubules,...
Source: Biochemical Society Transactions - June 22, 2023 Category: Biochemistry Authors: Irfan Saadi Jeremy P Goering Brittany M Hufft-Martinez Pamela V Tran Source Type: research
SPECC1L: a cytoskeletal protein that regulates embryonic tissue dynamics
Biochem Soc Trans. 2023 Jun 22:BST20220461. doi: 10.1042/BST20220461. Online ahead of print.ABSTRACTMany structural birth defects occur due to failure of tissue movement and fusion events during embryogenesis. Examples of such birth defects include failure of closure of the neural tube, palate, and ventral body wall. Actomyosin forces play a pivotal role in these closure processes, making proteins that regulate actomyosin dynamics a priority when studying the etiology of structural birth defects. SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1 like) cytoskeletal protein associates with microtubules,...
Source: Biochemical Society Transactions - June 22, 2023 Category: Biochemistry Authors: Irfan Saadi Jeremy P Goering Brittany M Hufft-Martinez Pamela V Tran Source Type: research
SPECC1L: a cytoskeletal protein that regulates embryonic tissue dynamics
Biochem Soc Trans. 2023 Jun 22:BST20220461. doi: 10.1042/BST20220461. Online ahead of print.ABSTRACTMany structural birth defects occur due to failure of tissue movement and fusion events during embryogenesis. Examples of such birth defects include failure of closure of the neural tube, palate, and ventral body wall. Actomyosin forces play a pivotal role in these closure processes, making proteins that regulate actomyosin dynamics a priority when studying the etiology of structural birth defects. SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1 like) cytoskeletal protein associates with microtubules,...
Source: Biochemical Society Transactions - June 22, 2023 Category: Biochemistry Authors: Irfan Saadi Jeremy P Goering Brittany M Hufft-Martinez Pamela V Tran Source Type: research
SPECC1L: a cytoskeletal protein that regulates embryonic tissue dynamics
Biochem Soc Trans. 2023 Jun 28;51(3):949-958. doi: 10.1042/BST20220461.ABSTRACTMany structural birth defects occur due to failure of tissue movement and fusion events during embryogenesis. Examples of such birth defects include failure of closure of the neural tube, palate, and ventral body wall. Actomyosin forces play a pivotal role in these closure processes, making proteins that regulate actomyosin dynamics a priority when studying the etiology of structural birth defects. SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1 like) cytoskeletal protein associates with microtubules, filamentous actin, n...
Source: Biochemical Society Transactions - June 22, 2023 Category: Biochemistry Authors: Irfan Saadi Jeremy P Goering Brittany M Hufft-Martinez Pamela V Tran Source Type: research
SPECC1L: a cytoskeletal protein that regulates embryonic tissue dynamics
Biochem Soc Trans. 2023 Jun 28;51(3):949-958. doi: 10.1042/BST20220461.ABSTRACTMany structural birth defects occur due to failure of tissue movement and fusion events during embryogenesis. Examples of such birth defects include failure of closure of the neural tube, palate, and ventral body wall. Actomyosin forces play a pivotal role in these closure processes, making proteins that regulate actomyosin dynamics a priority when studying the etiology of structural birth defects. SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1 like) cytoskeletal protein associates with microtubules, filamentous actin, n...
Source: Biochemical Society Transactions - June 22, 2023 Category: Biochemistry Authors: Irfan Saadi Jeremy P Goering Brittany M Hufft-Martinez Pamela V Tran Source Type: research
