Mutation of FLNA attenuating the migration of abdominal muscles contributed to Melnick-Needles syndrome (MNS) in a family with recurrent miscarriage
CONCLUSION: Our research revealed a mutation site of the FLNA for MNS and explored the mechanism of midline structure dysplasia in the abdominal wall of male patients, which could provide more evidence for the clinical diagnosis and genetic counseling of families with these disorders.PMID:36734119 | DOI:10.1002/mgg3.2145 (Source: Molecular Medicine)
Source: Molecular Medicine - February 3, 2023 Category: Molecular Biology Authors: Xin Luo Zailin Yang Jing Zeng Jing Chen Ningxuan Chen Xiaoyan Jiang Qinlv Wei Ping Yi Jing Xu Source Type: research

Cone-beam computed tomography –assisted percutaneous gastrostomy tube insertion in children with challenging anatomy
ConclusionThis study shows that cone-beam CT guidance can be useful for assisting percutaneous radiologic gastrostomy in children with challenging anatomy. (Source: Pediatric Radiology)
Source: Pediatric Radiology - February 1, 2023 Category: Radiology Source Type: research

Impact of Social Vulnerability on Long-Term Growth Outcomes in Sutureless Versus Sutured Repair of Gastroschisis
Conclusion Sutureless and sutured gastroschisis repairs result in similar growth and long-term outcomes. Patients living in areas with greater social vulnerability may be at increased risk of poor weight gain. Patients should be followed at least through their first year to ensure appropriate growth. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: European Journal of Pediatric Surgery)
Source: European Journal of Pediatric Surgery - January 31, 2023 Category: Surgery Authors: Barry, Mark Gozali, Aileen Vu, Lan Tags: Original Article Source Type: research

Gastroschisis in Mozambique: current status and priorities for improving care from Hospital  Central de Maputo, the largest and referral hospital of the country
ConclusionWhile the mortality rate remains high for gastroschisis patients in Mozambique, there have been a few survivors when surgery is performed. Improvements in neonatal care are needed. Given the high mortality rates and limited resources, we plan to focus our surgical efforts on bedside closure techniques. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - January 30, 2023 Category: Surgery Source Type: research

Gastroschisis Outcomes: Presence of Histologic Chorioamnionitis and the Impact on Time to Full Enteral Feeds and Length of Hospital Stay
Conclusion Acute placental inflammation during the perinatal period does not impact the infant's time to achieve full feeds or prolong their hospital stay. Larger studies are needed to confirm these findings. Key Points [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - January 29, 2023 Category: Perinatology & Neonatology Authors: Ejiofor, Chukwudi O. Ford, Steven Duncan, Jose R. Rideout, Drew Kumar, Ambuj Donda, Keyur Flores-Torres, Jaime Tags: Original Article Source Type: research

Fetal Risks and Morbidity in Pregnant Individuals with Obesity
AbstractPurpose of ReviewTo provide an up-to-date summary on the fetal risks associated with maternal obesity, specifically the risks of fetal anomalies, abnormal fetal growth, and stillbirth.Recent FindingsWith the emerging data on fetal outcomes in individuals with the highest class of obesity, there is growing evidence that for many fetal adverse outcomes, there is a direct relationship between increasing maternal obesity class and the severity of the fetal outcome.SummaryMaternal obesity is associated with an increased risk of various fetal anomalies including fetal congenital cardiac disease, although there is a decre...
Source: Current Obstetrics and Gynecology Reports - January 26, 2023 Category: OBGYN Source Type: research

The Alberta Congenital Anomalies Surveillance System: a 40-year review with prevalence and trends for selected congenital anomalies, 1997-2019
CONCLUSION: Congenital anomalies are an important public health concern with significant social and societal costs. Surveillance data gathered by ACASS for over 40 years can be used for planning and policy decisions and the evaluation of prevention strategies. Contributing genetic and environmental factors are discussed as is the need for continued surveillance and research.PMID:36651885 | DOI:10.24095/hpcdp.43.1.04 (Source: Health Promotion and Chronic Disease Prevention in Canada)
Source: Health Promotion and Chronic Disease Prevention in Canada - January 18, 2023 Category: International Medicine & Public Health Authors: R Brian Lowry Tanya Bedard Xin Grevers Susan Crawford Steven C Greenway Mary E Brindle Harvey B Sarnat A Robertson Harrop Gerhard N Kiefer Mary Ann Thomas Source Type: research