Maternal physical activity, sitting, and risk of non-cardiac birth defects
CONCLUSIONS: Reasonable next steps include replication of these findings, improved exposure assessment, and elucidation of biologic mechanisms.IMPACT: Using data from two population-based case-control studies, we found that mothers engaging in different types of physical activity in the 3 months before pregnancy had an infant with a reduced odds of five and a higher odds of two birth defects. Mothers spending less time sitting in the 3 months before pregnancy had an infant with a reduced odds of two and a higher odds of one birth defect. Clarification and confirmation from additional studies are needed using more precise e...
Source: Pediatric Research - August 5, 2023 Category: Pediatrics Authors: Kelly R Evenson Sanjida Mowla Andrew F Olshan Gary M Shaw Elizabeth C Ailes Jennita Reefhuis Neha Joshi Tania A Desrosiers National Birth Defects Prevention Study and Birth Defects Study To Evaluate Pregnancy exposureS Source Type: research

Maternal physical activity, sitting, and risk of non-cardiac birth defects
CONCLUSIONS: Reasonable next steps include replication of these findings, improved exposure assessment, and elucidation of biologic mechanisms.IMPACT: Using data from two population-based case-control studies, we found that mothers engaging in different types of physical activity in the 3 months before pregnancy had an infant with a reduced odds of five and a higher odds of two birth defects. Mothers spending less time sitting in the 3 months before pregnancy had an infant with a reduced odds of two and a higher odds of one birth defect. Clarification and confirmation from additional studies are needed using more precise e...
Source: Pediatric Research - August 5, 2023 Category: Pediatrics Authors: Kelly R Evenson Sanjida Mowla Andrew F Olshan Gary M Shaw Elizabeth C Ailes Jennita Reefhuis Neha Joshi Tania A Desrosiers National Birth Defects Prevention Study and Birth Defects Study To Evaluate Pregnancy exposureS Source Type: research

Prevalence and Spatial Distribution of Gastroschisis in an Industrial Watershed
We examined gastroschisis incidence, risk factors, and spatial association in a geographic region with known environmental pollution and hazardous waste sites. An observational study of fetal and neonatal gastroschisis diagnosed from 1/1/2006 to 12/31/2020 was conducted in a southern West Virginia (WV) tertiary care hospital. Emerging hot spot analysis and Ripley's K-Function examined the spatial relationship between gastroschisis cases and Environmental Protection Agency (EPA) Federal Registry Sites (FRS). A total of 63 gastroschisis cases provided a prevalence rate of 14.6 per 10000 live births. Gastroschisis was associa...
Source: The American Surgeon - July 26, 2023 Category: Surgery Authors: Jacob Minor Amy Wells Krysta Orminski Stephanie N Thompson Frank Annie Lindsey Robinson Byron C Calhoun Ramanathapura N Haricharan Source Type: research

Prevalence and Spatial Distribution of Gastroschisis in an Industrial Watershed
We examined gastroschisis incidence, risk factors, and spatial association in a geographic region with known environmental pollution and hazardous waste sites. An observational study of fetal and neonatal gastroschisis diagnosed from 1/1/2006 to 12/31/2020 was conducted in a southern West Virginia (WV) tertiary care hospital. Emerging hot spot analysis and Ripley's K-Function examined the spatial relationship between gastroschisis cases and Environmental Protection Agency (EPA) Federal Registry Sites (FRS). A total of 63 gastroschisis cases provided a prevalence rate of 14.6 per 10000 live births. Gastroschisis was associa...
Source: The American Surgeon - July 26, 2023 Category: Surgery Authors: Jacob Minor Amy Wells Krysta Orminski Stephanie N Thompson Frank Annie Lindsey Robinson Byron C Calhoun Ramanathapura N Haricharan Source Type: research

Prenatal Exposure to Cannabis and Risk of Major Structural Birth Defects: A Systematic Review and Meta-analysis
CONCLUSION: Studies examining associations between prenatal exposure to cannabis and major structural birth defects were heterogeneous. Most published effect estimates were unadjusted and scored low on our risk-of-bias assessment. Overall, we found inconsistent evidence to suggest that prenatal cannabis exposure is associated with birth defects. However, findings related to specific anomalies should be considered in further research.SYSTEMATIC REVIEW REGISTRATION: PROSPERO, CRD42022319041.PMID:37473409 | DOI:10.1097/AOG.0000000000005252 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - July 20, 2023 Category: OBGYN Authors: Erin Delker Shana Hayes Ann E Kelly Kenneth L Jones Christina Chambers Gretchen Bandoli Source Type: research

Surgery cannot change the outcome of all infants with omphalocele
Asian J Surg. 2023 Jul 18:S1015-9584(23)01044-8. doi: 10.1016/j.asjsur.2023.07.064. Online ahead of print.NO ABSTRACTPMID:37474380 | DOI:10.1016/j.asjsur.2023.07.064 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - July 20, 2023 Category: Surgery Authors: Guangguo Men Lili Wang Xudan Lu Source Type: research

Prenatal Exposure to Cannabis and Risk of Major Structural Birth Defects: A Systematic Review and Meta-analysis
CONCLUSION: Studies examining associations between prenatal exposure to cannabis and major structural birth defects were heterogeneous. Most published effect estimates were unadjusted and scored low on our risk-of-bias assessment. Overall, we found inconsistent evidence to suggest that prenatal cannabis exposure is associated with birth defects. However, findings related to specific anomalies should be considered in further research.SYSTEMATIC REVIEW REGISTRATION: PROSPERO, CRD42022319041.PMID:37473409 | DOI:10.1097/AOG.0000000000005252 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - July 20, 2023 Category: OBGYN Authors: Erin Delker Shana Hayes Ann E Kelly Kenneth L Jones Christina Chambers Gretchen Bandoli Source Type: research

Surgery cannot change the outcome of all infants with omphalocele
Asian J Surg. 2023 Jul 18:S1015-9584(23)01044-8. doi: 10.1016/j.asjsur.2023.07.064. Online ahead of print.NO ABSTRACTPMID:37474380 | DOI:10.1016/j.asjsur.2023.07.064 (Source: Asian Journal of Surgery)
Source: Asian Journal of Surgery - July 20, 2023 Category: Surgery Authors: Guangguo Men Lili Wang Xudan Lu Source Type: research

Prenatal Exposure to Cannabis and Risk of Major Structural Birth Defects: A Systematic Review and Meta-analysis
CONCLUSION: Studies examining associations between prenatal exposure to cannabis and major structural birth defects were heterogeneous. Most published effect estimates were unadjusted and scored low on our risk-of-bias assessment. Overall, we found inconsistent evidence to suggest that prenatal cannabis exposure is associated with birth defects. However, findings related to specific anomalies should be considered in further research.SYSTEMATIC REVIEW REGISTRATION: PROSPERO, CRD42022319041.PMID:37473409 | DOI:10.1097/AOG.0000000000005252 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - July 20, 2023 Category: OBGYN Authors: Erin Delker Shana Hayes Ann E Kelly Kenneth L Jones Christina Chambers Gretchen Bandoli Source Type: research

Prenatal Exposure to Cannabis and Risk of Major Structural Birth Defects: A Systematic Review and Meta-analysis
CONCLUSION: Studies examining associations between prenatal exposure to cannabis and major structural birth defects were heterogeneous. Most published effect estimates were unadjusted and scored low on our risk-of-bias assessment. Overall, we found inconsistent evidence to suggest that prenatal cannabis exposure is associated with birth defects. However, findings related to specific anomalies should be considered in further research.SYSTEMATIC REVIEW REGISTRATION: PROSPERO, CRD42022319041.PMID:37473409 | DOI:10.1097/AOG.0000000000005252 (Source: Obstetrics and Gynecology)
Source: Obstetrics and Gynecology - July 20, 2023 Category: OBGYN Authors: Erin Delker Shana Hayes Ann E Kelly Kenneth L Jones Christina Chambers Gretchen Bandoli Source Type: research

Evaluation of quality of care in neonatal anesthesia using a bundle of intraoperative parameters
CONCLUSION: Although a median of six out of the seven selected intraoperative parameters were monitored during gastroschisis repair, only two of them (oxygen saturation and heart rate) were maintained within the pre-defined range more than 80% of the time. It might be of interest to extend physiologic age- and procedure-based approach to the development of specific preoperative anesthetic planning.PMID:37422704 | DOI:10.1111/pan.14719 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - July 9, 2023 Category: Anesthesiology Authors: Jean-Philippe Sala ün Roxane Beaufils Audrey Chagnot C énéric Alexandre Thierry Petit Jean-Luc Hanouz Gilles Orliaguet Source Type: research

Evaluation of quality of care in neonatal anesthesia using a bundle of intraoperative parameters
CONCLUSION: Although a median of six out of the seven selected intraoperative parameters were monitored during gastroschisis repair, only two of them (oxygen saturation and heart rate) were maintained within the pre-defined range more than 80% of the time. It might be of interest to extend physiologic age- and procedure-based approach to the development of specific preoperative anesthetic planning.PMID:37422704 | DOI:10.1111/pan.14719 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - July 9, 2023 Category: Anesthesiology Authors: Jean-Philippe Sala ün Roxane Beaufils Audrey Chagnot C énéric Alexandre Thierry Petit Jean-Luc Hanouz Gilles Orliaguet Source Type: research

Evaluation of quality of care in neonatal anesthesia using a bundle of intraoperative parameters
CONCLUSION: Although a median of six out of the seven selected intraoperative parameters were monitored during gastroschisis repair, only two of them (oxygen saturation and heart rate) were maintained within the pre-defined range more than 80% of the time. It might be of interest to extend physiologic age- and procedure-based approach to the development of specific preoperative anesthetic planning.PMID:37422704 | DOI:10.1111/pan.14719 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - July 9, 2023 Category: Anesthesiology Authors: Jean-Philippe Sala ün Roxane Beaufils Audrey Chagnot C énéric Alexandre Thierry Petit Jean-Luc Hanouz Gilles Orliaguet Source Type: research

Evaluation of quality of care in neonatal anesthesia using a bundle of intraoperative parameters
CONCLUSION: Although a median of six out of the seven selected intraoperative parameters were monitored during gastroschisis repair, only two of them (oxygen saturation and heart rate) were maintained within the pre-defined range more than 80% of the time. It might be of interest to extend physiologic age- and procedure-based approach to the development of specific preoperative anesthetic planning.PMID:37422704 | DOI:10.1111/pan.14719 (Source: Paediatric Anaesthesia)
Source: Paediatric Anaesthesia - July 9, 2023 Category: Anesthesiology Authors: Jean-Philippe Sala ün Roxane Beaufils Audrey Chagnot C énéric Alexandre Thierry Petit Jean-Luc Hanouz Gilles Orliaguet Source Type: research