Revisiting QT prolongation in acute rheumatic fever – Relevance for hydroxychloroquine treatment
In-vitro evidence suggests hydroxychloroquine could be a potential immunomodulator for the inflammatory carditis of acute rheumatic fever (ARF). Hydroxychloroquine used as an anti-inflammatory agent has a low side effect profile but its use in the Covid-19 pandemic raised concerns about QTc interval prolongation and cardiac arrhythmias. The prolongation of QTc in ARF appears benign but has not been widely studied. We aim to report QTc intervals in a contemporary ARF population and consider implications for hydroxychloroquine use in ARF.
Source: International Journal of Cardiology - Category: Cardiology Authors: Fiona Perelini, Joshua Agnew, Jonathan R. Skinner, Dug Yeo Han, Ross Nicholson, Nigel Wilson Tags: Short communication Source Type: research
More News: Arrhythmia | Cardiac Arrhythmia | Cardiology | COVID-19 | Heart | Hydroxychloroquine | Pandemics | Rheumatology