A Systematic Review and Meta-Analysis of Studies of Defibrotide Prophylaxis for Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome

ConclusionsThis analysis suggests a low incidence of VOD/SOS following intravenous defibrotide prophylaxis, regardless of age group, and a lower relative risk for VOD/SOS with defibrotide prophylaxis vs controls in patient populations at high risk of VOD/SOS.

http://link.springer.com/10.1007/s40261-022-01140-y

Source: Clinical Drug Investigation - May 20, 2022 Category: Drugs & Pharmacology Source Type: research