LMP2A inhibits the expression of KLF5 through the mTORC1 pathway in EBV-associated gastric carcinoma

CONCLUSION: LMP2A downregulated KLF5 expression by inhibiting the mTORC1 pathway in EBV positive GC cells. KLF5 might play an oncogene-like role by promoting the migration of GC cells and inducing autophagy.PMID:35500764 | DOI:10.1016/j.virusres.2022.198792

Source: Virus Research - May 2, 2022 Category: Virology Authors: Dandan Liu Duo Shi Lin Xu Lingling Sun Shuzhen Liu Bing Luo Source Type: research