Cardiac Rehabilitation Improves Endothelial Function in Coronary Artery Disease Patients
Int J Sports Med DOI: 10.1055/a-1717-1798Exercise-based cardiac rehabilitation may be an effective non-pharmacological
intervention for improving endothelial function in coronary artery disease
patients. Therefore, this systematic review with meta-analysis aimed to (a)
estimate the training-induced effect on endothelial and vascular smooth muscle
function, assessed by flow-mediated dilation and nitroglycerin-mediated
dilation, respectively, in coronary artery disease patients; and to (b) study
the influence of potential trial-level variables (i. e. study and
intervention characteristics) on the training-induced effect on endothelial and
vascular smooth muscle function. Electronic searches were performed in Pubmed,
Scopus, and Embase up to February 2021. Random-effects models of standardised
mean change were estimated. Heterogeneity analyses were performed by using the
Chi
2
test and I
2
index.
Our results showed that exercise-based cardiac rehabilitation significantly
enhanced flow-mediated dilation (1.04 [95% confidence
interval=0.76 to 1.31]) but did not significantly change
nitroglycerin-mediated dilation (0.05 [95% confidence
interval=–0.03 to 0.13]). Heterogeneity testing reached
statistical significance (p<.001) with high inconsistency for
flow-medi...
Source: International Journal of Sports Medicine - Category: Sports Medicine Authors: Manresa-Rocamora, Agust ín Ribeiro, Fernando Casanova-Liz ón, Antonio Flatt, Andrew A. Sarabia, Jos é Manuel Moya-Ram ón, Manuel Tags: Review Source Type: research
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