Senolytics Cocktail Dasatinib and Quercetin Alleviate Human Umbilical Vein Endothelial Cell Senescence via the TRAF6-MAPK-NF- κB Axis in a YTHDF2-Dependent Manner

Conclusion: Collectively, we first identified that D+Q alleviate LPS-induced senescence in HUVECs via the TRAF6-MAPK-NF- κB axis in a YTHDF2-dependent manner, providing novel ideas for clinical treatment of age-related cardiovascular diseases.Gerontology

https://www.karger.com/Article/FullText/522656

Source: Gerontology - April 25, 2022 Category: Geriatrics Source Type: research