HDAC4 Mediates Smoking-Induced Pancreatic Cancer Metastasis

Conclusions We found that HDAC4 is the only HDAC induced by smoking among all HDACs analyzed. We found that smoking promotes invasion and metastasis of PDAC cells through a mechanism that involves HDAC4 and that HDAC4 is a promising target for preventing PDAC metastasis.
Source: Pancreas - Category: Gastroenterology Tags: Original Articles Source Type: research