A ‘Swine Time’ for HFpEF: Multiple animal models for a myriad of clinical phenotypes

“Check yourself before you wreck yourself” - sage words for any researcher using animal models to study heart failure with preserved ejection fraction (HFpEF). Those who have conducted animal studies examining HFpEF are likely familiar with “Jekyll and Hyde” responses spanning “that totall y mimics HFpEF disease pathology” to “that in no way, shape, or form reflects HFpEF”. This extreme commentary has diminished, as a heterogenous collection of clinical risk factors has uncovered a diverse array of HFpEF phenotypes.
Source: Journal of Molecular and Cellular Cardiology - Category: Cytology Authors: Tags: Letter to the editor Source Type: research