Cancers, Vol. 14, Pages 1485: Fertility Sparing Surgery and Borderline Ovarian Tumours

Cancers, Vol. 14, Pages 1485: Fertility Sparing Surgery and Borderline Ovarian Tumours Cancers doi: 10.3390/cancers14061485 Authors: Lorraine S. Kasaven Mehar Chawla Benjamin P. Jones Maya Al-Memar Nicolas Galazis Yousra Ahmed-Salim Mona El-Bahrawy Stuart Lavery Srdjan Saso Joseph Yazbek To determine the oncological outcomes following fertility-sparing surgery (FSS) for the management of Borderline Ovarian Tumours (BOTs). A retrospective analysis of participants diagnosed with BOTs between January 2004 and December 2020 at the West London Gynaecological Oncology Centre was conducted. A total of 172 women were diagnosed; 52.3% (90/172) underwent FSS and 47.7% (82/172) non-FSS. The overall recurrence rate of disease was 16.9% (29/172), of which 79.3% (23/29) presented as the recurrence of serous or sero-mucinous BOTs and 20.7% (6/29) as low-grade serous carcinoma (LGSC). In the FSS group, the recurrence rate of BOTs was 25.6% (23/90) presenting a median 44.0 (interquartile range (IQR) 41.5) months, of which there were no episodes of recurrence presenting as LGSC reported. In the non-FSS group, all recurrences of disease presented as LGSC, with a rate of 7.7% (6/78), following a median of 47.5 months (IQR 47.8). A significant difference between the type of surgery performed (FSS v Non-FSS) and the association with recurrence of BOT was observed (Pearson Chi-Square: p = 0.000; x = 20.613). Twelve women underwent ultrasound-guided ovarian wedge resection ...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research