CSB-independent, XPC-dependent transcription-coupled repair in Drosophila [Biochemistry]

Drosophila melanogaster has been extensively used as a model system to study ionizing radiation and chemical-induced mutagenesis, double-strand break repair, and recombination. However, there are only limited studies on nucleotide excision repair in this important model organism. An early study reported that Drosophila lacks the transcription-coupled repair (TCR) form of...

Source: Proceedings of the National Academy of Sciences - February 25, 2022 Category: Science Authors: Nazli Deger, Xuemei Cao, Christopher P. Selby, Saygin Gulec, Hiroaki Kawara, Evan B. Dewey, Li Wang, Yanyan Yang, Sierra Archibald, Berkay Selcuk, Ogun Adebali, Jeff Sekelsky, Aziz Sancar, Zhenxing Liu Tags: Biochemistry Biological Sciences Source Type: research