Nematode ascarosides attenuate mammalian type 2 inflammatory responses [Immunology and Inflammation]

Mounting evidence suggests that nematode infection can protect against disorders of immune dysregulation. Administration of live parasites or their excretory/secretory (ES) products has shown therapeutic effects across a wide range of animal models for immune disorders, including asthma. Human clinical trials of live parasite ingestion for the treatment of immune...

Source: Proceedings of the National Academy of Sciences - February 24, 2022 Category: Science Authors: Kenta Shinoda, Andrea Choe, Kiyoshi Hirahara, Masahiro Kiuchi, Kota Kokubo, Tomomi Ichikawa, Jason S. Hoki, Akane S. Suzuki, Neelanjan Bose, Judith A. Appleton, Raffi V. Aroian, Frank C. Schroeder, Paul W. Sternberg, Toshinori Nakayama Tags: Immunology and Inflammation Biological Sciences Source Type: research