Growth differentiation factor-11 downregulates steroidogenic acute regulatory protein expression through ALK5-mediated SMAD3 signaling pathway in human granulosa-lutein cells

CONCLUSIONS: This study increases the understanding of the biological function of GDF-11 and provides important insights into the regulation of ovarian steroidogenesis.PMID:35183204 | DOI:10.1186/s12958-022-00912-7

Source: Reproductive Biology - February 20, 2022 Category: Reproduction Medicine Authors: Qiongqiong Jia Boqun Liu Xuan Dang Yanjie Guo Xiaoyu Han Tinglin Song Jung-Chien Cheng Lanlan Fang Source Type: research