Effect of intravenous thrombolysis in acute ischemic stroke patients with cerebral microbleeds and analysis of risk factors for hemorrhagic transformation

CONCLUSIONS: Compared with those undergoing no intravenous thrombolysis with rt-PA, patients with acute ischemic stroke and CMB who received intravenous thrombolysis with rt-PA exhibit significantly improved short-term neurological function recovery and long-term prognosis, but the incidence and mortality rates of ICH have no statistically significant differences. Moreover, the time from stroke onset to thrombolysis, baseline NIHSS score, and history of atrial fibrillation are independent risk factors affecting the HT of patients treated with intravenous thrombolysis.PMID:35179744 | DOI:10.26355/eurrev_202202_27986

Source: European Review for Medical and Pharmacological Sciences - February 18, 2022 Category: Drugs & Pharmacology Authors: Y-S Lei H Li J-Y Lei S-X Li D-F Li Source Type: research