Effects and Mechanism of Action of Panax notoginseng Saponins on the Pharmacokinetics of Warfarin

ConclusionPNS can increase the blood concentration of warfarin, as well as the exposure time, and it can enhance the anticoagulant effect of warfarin by inhibiting the expression of the liver enzyme CYP3A4.

Source: European Journal of Drug Metabolism and Pharmacokinetics - February 9, 2022 Category: Drugs & Pharmacology Source Type: research